Basis: Trailing twelve months (TTM). Source: stored company filings and market data; unavailable inputs remain N/A.
Is the gross margin high or low?
The gross margin of 98.16% is in line with its 5-year average of 98.30%, around the middle of its 5-year range (96.06%–99.49%).
0.13% below its 12-month average of 98.28%.
Reported quarterly gross margin; no daily interpolation. Q2 FY2026 (2026-06-30): 98.98%.
GROSS MARGIN
98.16%
GROSS MARGIN AVG TTM
98.28%
GROSS MARGIN AVG 3Y
98.69%
GROSS MARGIN AVG 5Y
98.30%
GROSS MARGIN AVG 10Y
98.57%
GROSS MARGIN AVG 15Y
55.75%
GROSS MARGIN AVG 20Y
54.61%
CURRENT VS TTM AVG
-0.13%
CURRENT VS 3Y AVG
-0.54%
CURRENT VS 5Y AVG
-0.14%
CURRENT VS 10Y AVG
-0.42%
CURRENT VS 15Y AVG
+76.06%
CURRENT VS 20Y AVG
+79.75%
SECTOR MEDIAN · HEALTHCARE
42.91%
median of 598 covered companies
CURRENT VS SECTOR MEDIAN
+128.76%
vs the sector median at left
Ionis Pharmaceuticals, Inc.
Market Cap
$7.27B
Gross Margin
98.16%
TTM Avg
98.28%
3Y Avg
98.69%
5Y Avg
98.30%
Market Cap
$7.52B
Gross Margin
84.52%
TTM Avg
78.41%
3Y Avg
74.39%
5Y Avg
74.39%
Market Cap
$7.61B
Gross Margin
84.97%
TTM Avg
-824.36%
3Y Avg
-1521.85%
5Y Avg
-1048.03%
Market Cap
$6.53B
Gross Margin
60.14%
TTM Avg
62.77%
3Y Avg
60.62%
5Y Avg
54.58%
Market Cap
$6.55B
Gross Margin
73.84%
TTM Avg
76.65%
3Y Avg
78.21%
5Y Avg
76.94%
| NAME | MARKET CAP | GROSS MARGIN | TTM | 3Y | 5Y |
|---|---|---|---|---|---|
| Ionis Pharmaceuticals, Inc. (IONS) | $7.27B | 98.16% | 98.28% | 98.69% | 98.30% |
| Hinge Health, Inc. (HNGE)vs › | $7.52B | 84.52% | 78.41% | 74.39% | 74.39% |
| HealthEquity, Inc. (HQY)vs › | $7.59B | 75.21% | 63.63% | 56.54% | 52.91% |
| Cytokinetics, Incorporated (CYTK)vs › | $7.61B | 84.97% | -824.36% | -1521.85% | -1048.03% |
| Alkermes plc (ALKS)vs › | $6.95B | 84.56% | 85.47% | 84.03% | 83.69% |
| Chemed Corporation (CHE)vs › | $6.67B | 30.44% | 32.55% | 34.06% | 34.32% |
| Immunovant, Inc. (IMVT)vs › | $6.62B | 0.00% | 0.00% | 0.00% | 0.00% |
| Lantheus Holdings, Inc. (LNTH)vs › | $6.53B | 60.14% | 62.77% | 60.62% | 54.58% |
| Hims & Hers Health, Inc. (HIMS)vs › | $6.55B | 73.84% | 76.65% | 78.21% | 76.94% |
| Amneal Pharmaceuticals, Inc. (AMRX)vs › | $6.41B | 39.32% | 37.08% | 36.51% | 35.71% |
Gross Margin
98.2%
(Revenue - COGS) / Revenue
Gross Margin = Gross Profit / Revenue
Gross margin is the percentage of revenue remaining after the cost of goods sold, reflecting core product profitability.
Expanded definitions: Investopedia, Wikipedia, Corporate Finance Institute
| DATE | GROSS MARGIN |
|---|---|
| 2026-06-30 | 98.98% |
| 2026-03-31 | 98.79% |
| 2025-12-31 | 96.06% |
| 2025-09-30 | 98.51% |
| 2025-06-30 | 99.08% |
| 2025-03-31 | 98.86% |
| 2024-12-31 | 98.31% |
| 2024-09-30 | 99.20% |
| 2024-06-30 | 98.15% |
| 2024-03-31 | 98.20% |
| 2023-12-31 | 99.06% |
| 2023-09-30 | 98.48% |
| 2023-06-30 | 98.65% |
| 2023-03-31 | 98.97% |
| 2022-12-31 | 97.57% |
| 2022-09-30 | 99.05% |
| 2022-06-30 | 96.45% |
| 2022-03-31 | 97.06% |
| 2021-12-31 | 99.49% |
| 2021-09-30 | 97.69% |
| 2021-06-30 | 97.65% |
| 2021-03-31 | 97.69% |
| 2020-12-31 | 98.86% |
| 2020-09-30 | 98.07% |
| 2020-06-30 | 97.93% |
| 2020-03-31 | 98.09% |
| 2019-12-31 | 99.80% |
| 2019-09-30 | 99.42% |
| 2019-06-30 | 99.17% |
| 2019-03-31 | 99.65% |
| 2018-12-31 | 40.00% |
| 2018-09-30 | 100.00% |
| 2018-06-30 | 100.00% |
| 2018-03-31 | 100.00% |
| 2017-12-31 | 25.54% |
| 2017-09-30 | 32.20% |
| 2017-06-30 | 25.62% |
| 2017-03-31 | 28.64% |
| 2016-12-31 | 36.92% |
| 2016-09-30 | 23.71% |
| 2016-06-30 | -101.65% |
| 2016-03-31 | -119.57% |
| 2015-12-31 | -96.49% |
| 2015-09-30 | -80.18% |
| 2015-06-30 | 43.53% |
| 2015-03-31 | -2.98% |
| 2014-12-31 | 19.92% |
| 2014-09-30 | -38.63% |
| 2014-06-30 | -3.83% |
| 2014-03-31 | -89.79% |
| 2013-12-31 | -35.93% |
| 2013-09-30 | -93.60% |
| 2013-06-30 | -11.92% |
| 2013-03-31 | 11.64% |
| 2012-12-31 | -697.35% |
| 2012-09-30 | -215.07% |
| 2012-06-30 | 14.59% |
| 2012-03-31 | -66.62% |
| 2011-12-31 | 100.00% |
| 2011-09-30 | 100.00% |
| 2011-06-30 | 100.00% |
| 2011-03-31 | 100.00% |
| 2010-12-31 | 100.00% |
| 2010-09-30 | 100.00% |
| 2010-06-30 | 100.00% |
| 2010-03-31 | 100.00% |
| 2009-12-31 | 100.00% |
| 2009-09-30 | 100.00% |
| 2009-06-30 | 100.00% |
| 2009-03-31 | 100.00% |
| 2008-12-31 | 0.00% |
| 2008-09-30 | 100.00% |
| 2008-06-30 | 100.00% |
| 2008-03-31 | 100.00% |
| 2007-12-31 | 0.00% |
| 2007-09-30 | 0.00% |
| 2007-06-30 | 0.00% |
| 2007-03-31 | 0.00% |
| 2006-12-31 | 0.00% |
| 2006-09-30 | 0.00% |
| 2006-06-30 | 0.00% |
| 2006-03-31 | 0.00% |
| 2005-12-31 | 0.00% |
| 2005-09-30 | 0.00% |
| 2005-06-30 | 0.00% |
| 2005-03-31 | 0.00% |
| 2004-12-31 | 0.00% |
| 2004-09-30 | 0.00% |
| 2004-06-30 | 0.00% |
| 2004-03-31 | 0.00% |
| 2003-12-31 | 0.00% |
| 2003-09-30 | 0.00% |
| 2003-06-30 | 0.00% |
| 2003-03-31 | 0.00% |
| 2002-12-31 | 0.00% |
| 2002-09-30 | 0.00% |
