Which has grown faster, HQY or IONS?

Over the past five years, HQY grew revenue faster — HQY at a 12.96% CAGR versus IONS at 4.91%.

Is HQY or IONS more profitable?

HQY runs the higher net margin — HQY at 17.36% versus IONS at -64.64%.

How have HQY and IONS total returns compared?

Over the past 10 years, HQY delivered 9.16% and IONS delivered 1.80% annualized total return. Past performance doesn't predict future results.

HealthEquity, Inc. (HQY) vs Ionis Pharmaceuticals, Inc. (IONS)

A side-by-side comparison of HealthEquity, Inc. and Ionis Pharmaceuticals, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

HQY

HealthEquity, Inc.

$7.61B

$91.05HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT

IONS

Ionis Pharmaceuticals, Inc.

$7.31B

$44.00HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT

Total return — HQY vs IONS

growth of $100 · dividends reinvested · last 10y

HQY +141.4% (+9.2%/yr)IONS +22.0% (+2.0%/yr)HQY compounded faster over this window

HQY IONS

HQY vs IONS: by the numbers

•HQY is the larger company ($7.61B vs $7.31B market cap).
•HQY is profitable (17.36% net margin) while IONS runs a net loss (-64.64%).
•HQY grew revenue faster over the past five years (12.96% vs 4.91% CAGR).

Metrics side by side

Valuation

Metric	HQY	IONS
P/E ratio	32.87	N/A
Forward P/E	19.27	N/A
PEG ratio	0.40	N/A
P/S ratio	5.59	8.37
P/B ratio	3.82	16.63
EV / EBITDA	17.31	2.21
FCF yield	6.20%	N/A

Profitability

Metric	HQY	IONS
Gross margin	75.21%	98.16%
Operating margin	25.61%	-40.47%
Net margin	17.36%	-64.64%
ROE	11.88%	-128.44%
ROIC	8.55%	-20.37%

Growth (annualized)

Metric	HQY	IONS
Revenue CAGR (5Y)	12.96%	4.91%
EPS CAGR (5Y)	83.56%	N/A
FCF CAGR (5Y)	36.72%	N/A
Total return CAGR (5Y)	7.00%	5.82%

Frequently asked

Which has grown faster, HQY or IONS?: Over the past five years, HQY grew revenue faster — HQY at a 12.96% CAGR versus IONS at 4.91%.
Is HQY or IONS more profitable?: HQY runs the higher net margin — HQY at 17.36% versus IONS at -64.64%.
How have HQY and IONS total returns compared?: Over the past 10 years, HQY delivered 9.16% and IONS delivered 1.80% annualized total return. Past performance doesn't predict future results.

Go deeper

Full HQY analysis Full IONS analysis Interactive comparison tool

Dig into the metrics

HealthEquity P/E ratio HealthEquity ROE Ionis Pharmaceuticals ROE HealthEquity operating margin Ionis Pharmaceuticals operating margin HealthEquity revenue growth Ionis Pharmaceuticals revenue growth HealthEquity free cash flow Ionis Pharmaceuticals free cash flow

HealthEquity & Ionis Pharmaceuticals appear in these rankings

Highest FCF Yield Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.