Basis: Trailing twelve months (TTM), to the latest fiscal quarter end. Source: stored company filings and market data; unavailable inputs remain N/A.
Is the return on equity (ROE) high or low?
The return on equity (ROE) of -128.44% is 83% below its 5-year average of -70.26%, near the low end of its 5-year range (-138.70%–1.23%).
As of the fiscal period ended Tuesday, June 30, 2026. 80.02% below its 12-month average of -71.35%.
Trailing-twelve-month return on equity at each fiscal quarter end; no daily interpolation. Q2 FY2026 (2026-06-30): -128.44%.
RETURN ON EQUITY (ROE)
-128.44%
RETURN ON EQUITY (ROE) AVG TTM
-71.35%
RETURN ON EQUITY (ROE) AVG 3Y
-88.42%
RETURN ON EQUITY (ROE) AVG 5Y
-70.26%
RETURN ON EQUITY (ROE) AVG 10Y
-45.08%
RETURN ON EQUITY (ROE) AVG 15Y
-37.21%
RETURN ON EQUITY (ROE) AVG 20Y
-31.60%
CURRENT VS TTM AVG
-80.02%
CURRENT VS 3Y AVG
-45.26%
CURRENT VS 5Y AVG
-82.81%
CURRENT VS 10Y AVG
-184.91%
CURRENT VS 15Y AVG
-245.20%
CURRENT VS 20Y AVG
-306.41%
SECTOR MEDIAN · HEALTHCARE
-41.20%
median of 733 covered companies
CURRENT VS SECTOR MEDIAN
-211.74%
vs the sector median at left
Ionis Pharmaceuticals, Inc.
Market Cap
$7.33B
Return on Equity (ROE)
-128.44%
TTM Avg
-71.35%
3Y Avg
-88.42%
5Y Avg
-70.26%
Market Cap
$7.55B
Return on Equity (ROE)
31.68%
TTM Avg
-71.21%
3Y Avg
-55.91%
5Y Avg
-55.91%
Market Cap
$7.61B
Return on Equity (ROE)
11.88%
TTM Avg
7.39%
3Y Avg
4.04%
5Y Avg
2.40%
Market Cap
$7.62B
Return on Equity (ROE)
N/A
TTM Avg
277.25%
3Y Avg
262.80%
5Y Avg
141.77%
Market Cap
$7.00B
Return on Equity (ROE)
3.66%
TTM Avg
19.17%
3Y Avg
13.19%
5Y Avg
6.34%
Market Cap
$7.67B
Return on Equity (ROE)
-25.29%
TTM Avg
-37.79%
3Y Avg
-133.44%
5Y Avg
-103.64%
Market Cap
$7.93B
Return on Equity (ROE)
17.77%
TTM Avg
-40.95%
3Y Avg
-11.78%
5Y Avg
-8.64%
Market Cap
$7.91B
Return on Equity (ROE)
73.08%
TTM Avg
39.77%
3Y Avg
-73.65%
5Y Avg
-82.53%
Market Cap
$6.65B
Return on Equity (ROE)
33.11%
TTM Avg
27.03%
3Y Avg
27.48%
5Y Avg
31.41%
| NAME | MARKET CAP | RETURN ON EQUITY (ROE) | TTM | 3Y | 5Y |
|---|---|---|---|---|---|
| Ionis Pharmaceuticals, Inc. (IONS) | $7.33B | -128.44% | -71.35% | -88.42% | -70.26% |
| Hinge Health, Inc. (HNGE)vs › | $7.55B | 31.68% | -71.21% | -55.91% | -55.91% |
| HealthEquity, Inc. (HQY)vs › | $7.61B | 11.88% | 7.39% | 4.04% | 2.40% |
| Cytokinetics, Incorporated (CYTK)vs › | $7.62B | N/A | 277.25% | 262.80% | 141.77% |
| Alkermes plc (ALKS)vs › | $7.00B | 3.66% | 19.17% | 13.19% | 6.34% |
| Praxis Precision Medicines, Inc. (PRAX)vs › | $7.67B | -25.29% | -37.79% | -133.44% | -103.64% |
| Caris Life Sciences, Inc. (CAI)vs › | $7.93B | 17.77% | -40.95% | -11.78% | -8.64% |
| TG Therapeutics, Inc. (TGTX)vs › | $7.91B | 73.08% | 39.77% | -73.65% | -82.53% |
| Chemed Corporation (CHE)vs › | $6.65B | 33.11% | 27.03% | 27.48% | 31.41% |
| Hims & Hers Health, Inc. (HIMS)vs › | $6.52B | -43.83% | 25.09% | 5.57% | 0.40% |
ROE
-128.4%
ROA
-18.9%
ROE = Net Income / Total Shareholders' Equity
Return on equity measures how efficiently a company generates profit from shareholders' equity. Higher ROE indicates better capital efficiency.
Expanded definitions: Investopedia, Wikipedia, Corporate Finance Institute
| DATE | RETURN ON EQUITY (ROE) |
|---|---|
| 2026-06-30 | -128.44% |
| 2026-03-31 | -66.46% |
| 2025-12-31 | -77.90% |
| 2025-09-30 | -41.48% |
| 2025-06-30 | -42.46% |
| 2025-03-31 | -96.28% |
| 2024-12-31 | -77.15% |
| 2024-09-30 | -54.16% |
| 2024-06-30 | -138.70% |
| 2024-03-31 | -129.76% |
| 2023-12-31 | -94.72% |
| 2023-09-30 | -129.80% |
| 2023-06-30 | -72.15% |
| 2023-03-31 | -67.59% |
| 2022-12-31 | -47.08% |
| 2022-09-30 | 1.23% |
| 2022-06-30 | -4.51% |
| 2022-03-31 | -0.55% |
| 2021-12-31 | -3.71% |
| 2021-09-30 | -111.86% |
| 2021-06-30 | -91.90% |
| 2021-03-31 | -70.57% |
| 2020-12-31 | -57.85% |
| 2020-09-30 | 6.85% |
| 2020-06-30 | 10.55% |
| 2020-03-31 | 12.50% |
| 2019-12-31 | 20.00% |
| 2019-09-30 | 32.16% |
| 2019-06-30 | 31.44% |
| 2019-03-31 | 29.78% |
| 2018-12-31 | 26.12% |
| 2018-09-30 | -6.13% |
| 2018-06-30 | -5.98% |
| 2018-03-31 | -1.45% |
| 2017-12-31 | 2.14% |
| 2017-09-30 | 9.46% |
| 2017-06-30 | 18.14% |
| 2017-03-31 | -7.27% |
| 2016-12-31 | -86.93% |
| 2016-09-30 | -131.66% |
| 2016-06-30 | -204.10% |
| 2016-03-31 | -85.03% |
| 2015-12-31 | -43.97% |
| 2015-09-30 | 5.79% |
| 2015-06-30 | 7.76% |
| 2015-03-31 | -8.85% |
| 2014-12-31 | -15.12% |
| 2014-09-30 | -27.36% |
| 2014-06-30 | -25.13% |
| 2014-03-31 | -24.12% |
| 2013-12-31 | -16.03% |
| 2013-09-30 | -9.72% |
| 2013-06-30 | -12.98% |
| 2013-03-31 | -21.46% |
| 2012-12-31 | -35.83% |
| 2012-09-30 | -48.67% |
| 2012-06-30 | -46.74% |
| 2012-03-31 | -58.86% |
| 2011-12-31 | -49.47% |
| 2011-09-30 | -42.15% |
| 2011-06-30 | -30.31% |
| 2011-03-31 | -31.44% |
| 2010-12-31 | -25.05% |
| 2010-09-30 | -21.37% |
| 2010-06-30 | -20.35% |
| 2010-03-31 | -10.87% |
| 2009-12-31 | 56.54% |
| 2009-09-30 | 55.72% |
| 2009-06-30 | 60.25% |
| 2009-03-31 | 60.74% |
| 2008-12-31 | -24.69% |
| 2008-09-30 | -21.84% |
| 2008-06-30 | 5.98% |
| 2008-03-31 | -6.88% |
| 2007-06-30 | -106.37% |
| 2007-03-31 | -72.84% |
| 2006-12-31 | -66.95% |
| 2006-06-30 | -636.63% |
| 2004-06-30 | -859.81% |
| 2004-03-31 | -203.94% |
| 2003-12-31 | -141.41% |
| 2003-09-30 | -91.38% |
| 2003-06-30 | -71.63% |
