Hims & Hers Health, Inc. (HIMS) vs Ionis Pharmaceuticals, Inc. (IONS)
A side-by-side comparison of Hims & Hers Health, Inc. and Ionis Pharmaceuticals, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
HIMS
Hims & Hers Health, Inc.
$29.27HealthcareDelayed quote: Oct 6, 2026, 12:25 PM EDT
IONS
Ionis Pharmaceuticals, Inc.
$44.10HealthcareDelayed quote: Oct 6, 2026, 12:25 PM EDT
Total return — HIMS vs IONS
growth of $100 · dividends reinvested · last 7yHIMS +202.8% (+17.1%/yr)IONS -27.6% (-4.5%/yr)HIMS compounded faster over this window
HIMS IONS
HIMS vs IONS: by the numbers
- •IONS is the larger company ($7.33B vs $6.53B market cap).
- •Both run net losses; HIMS's is the smaller (-5.51% vs -64.64% net margin).
- •HIMS grew revenue faster over the past five years (67.47% vs 4.91% CAGR).
Metrics side by side
Valuation
| Metric | HIMS | IONS |
|---|---|---|
| P/S ratio | 2.53 | 8.39 |
| P/B ratio | 20.15 | 16.67 |
| EV / EBITDA | N/A | 2.22 |
| FCF yield | 1.38% | N/A |
Profitability
| Metric | HIMS | IONS |
|---|---|---|
| Gross margin | 73.84% | 98.16% |
| Operating margin | 4.50% | -40.47% |
| Net margin | -5.51% | -64.64% |
| ROE | -43.83% | -128.44% |
| ROIC | -4.30% | -20.37% |
Growth (annualized)
| Metric | HIMS | IONS |
|---|---|---|
| Revenue CAGR (5Y) | 67.47% | 4.91% |
| Total return CAGR (5Y) | 32.23% | 5.82% |
Frequently asked
- Which has grown faster, HIMS or IONS?
- Over the past five years, HIMS grew revenue faster — HIMS at a 67.47% CAGR versus IONS at 4.91%.
- How have HIMS and IONS total returns compared?
- Over the past 5 years, HIMS delivered 32.23% and IONS delivered 5.82% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Hims & Hers Health ROEIonis Pharmaceuticals ROEHims & Hers Health operating marginIonis Pharmaceuticals operating marginHims & Hers Health revenue growthIonis Pharmaceuticals revenue growthHims & Hers Health free cash flowIonis Pharmaceuticals free cash flow
Hims & Hers Health & Ionis Pharmaceuticals appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.