Ionis Pharmaceuticals (IONS) PE Ratio: History & Chart

Ionis Pharmaceuticals, Inc.(IONS)

Biotechnology · Carlsbad, CA

$44.00+0.50 (+1.15%)

Delayed quote: Oct 6, 2026, 4:00 PM EDT

About Ionis Pharmaceuticals, Inc.

Founded in 1989 and headquartered in Carlsbad, California, Ionis Pharmaceuticals, Inc. is a biopharmaceutical company specializing in the discovery and development of RNA-targeted therapies within the United States. Its commercial portfolio includes three key medications: SPINRAZA, prescribed for spinal muscular atrophy (SMA) in both children and adults; TEGSEDI, an injectable treatment targeting polyneuropathy associated with hereditary transthyretin-mediated amyloidosis in adult patients; and WAYLIVRA, which addresses familial chylomicronemia syndrome and familial partial lipodystrophy. Ionis also maintains a robust pipeline, with several drug candidates currently in Phase 3 clinical trials. These include Eplontersen, a monthly self-administered subcutaneous injection designed for all forms of TTR amyloidosis; Olezarsen, intended for individuals with severe hypertriglyceridemia (SHTG); Donidalorsen, for patients suffering from hereditary angioedema; ION363, aimed at amyotrophic lateral sclerosis (ALS); Pelacarsen, developed for those with established cardiovascular disease and elevated lipoprotein(a); and Tofersen, which works by inhibiting the production of superoxide dismutase 1. Beyond these late-stage assets, the company is actively researching treatments for metabolic, infectious, renal, and ophthalmic diseases, as well as various types of cancer. The firm engages in significant collaborations, notably a strategic partnership with Biogen Inc. Additionally, it holds licensing and collaboration agreements with AstraZeneca, Bayer AG, GlaxoSmithKline plc, Novartis AG, Roche, Janssen Biotech, Inc., and Flamingo Therapeutics, Inc.

Carlsbad, CA

1,480 employees

www.ionis.com

Healthcare / Biotechnology

Sector: Healthcare
Industry: Biotechnology
CEO: Brett Monia

View full financials

NAME	MARKET CAP	PE RATIO	TTM	3Y	5Y
Ionis Pharmaceuticals, Inc. (IONS)	$7.31B	N/A	66.44	36.31	68.82
Hinge Health, Inc. (HNGE)vs ›	$7.61B	76.44	71.23	44.77	44.77
HealthEquity, Inc. (HQY)vs ›	$7.61B	32.87	39.94	105.96	402.80
Cytokinetics, Incorporated (CYTK)vs ›	$7.63B	N/A	44.08	44.08	44.08
Alkermes plc (ALKS)vs ›	$6.99B	108.75	44.92	25.77	27.28
Caris Life Sciences, Inc. (CAI)vs ›	$7.76B	76.71	73.85	73.85	73.85
Praxis Precision Medicines, Inc. (PRAX)vs ›	$7.81B	N/A	N/A	N/A	N/A
Chemed Corporation (CHE)vs ›	$6.66B	25.59	23.86	27.91	28.44
TG Therapeutics, Inc. (TGTX)vs ›	$7.99B	19.05	21.60	190.21	190.21
Immunovant, Inc. (IMVT)vs ›	$6.63B	N/A	N/A	N/A	N/A

NAME

MARKET CAP

PE RATIO

TTM

Ionis Pharmaceuticals, Inc. (IONS)

$7.31B

N/A

66.44

36.31

68.82

Hinge Health, Inc. (HNGE)vs ›

$7.61B

76.44

71.23

44.77

HealthEquity, Inc. (HQY)vs ›

$7.61B

32.87

39.94

105.96

402.80

Cytokinetics, Incorporated (CYTK)vs ›

$7.63B

N/A

44.08

Alkermes plc (ALKS)vs ›

$6.99B

108.75

44.92

25.77

27.28

Caris Life Sciences, Inc. (CAI)vs ›

$7.76B

76.71

73.85

Praxis Precision Medicines, Inc. (PRAX)vs ›

$7.81B

N/A

Chemed Corporation (CHE)vs ›

$6.66B

25.59

23.86

27.91

28.44

TG Therapeutics, Inc. (TGTX)vs ›

$7.99B

19.05

21.60

190.21

Immunovant, Inc. (IMVT)vs ›

$6.63B

N/A

PE Ratio Formula & Definition

PE Ratio = Share Price / Diluted EPS (TTM)

The price-to-earnings ratio measures how much investors pay for each dollar of trailing earnings. A lower PE can indicate a cheaper valuation; a higher PE implies higher growth expectations.

PE Ratio FAQ

What is the P/E ratio for Ionis Pharmaceuticals, Inc. (IONS)?

The P/E ratio for IONS stock is N/A.

What is the TTM average P/E ratio for Ionis Pharmaceuticals, Inc. (IONS)?

The TTM average P/E ratio for IONS stock is 66.44.

What is the 3Y average P/E ratio for Ionis Pharmaceuticals, Inc. (IONS)?

The 3Y average P/E ratio for IONS stock is 36.31.

What is the 5Y average P/E ratio for Ionis Pharmaceuticals, Inc. (IONS)?

The 5Y average P/E ratio for IONS stock is 68.82.

What is the 10Y average P/E ratio for Ionis Pharmaceuticals, Inc. (IONS)?

The 10Y average P/E ratio for IONS stock is 137.91.

DATE	PE RATIO
2021-02-24	117.10
2021-02-23	116.77
2021-02-22	116.54
2021-02-19	120.19
2021-02-18	119.85
2021-02-17	121.46
2021-02-16	117.08
2021-02-12	118.87
2021-02-11	120.73
2021-02-10	121.02
2021-02-09	123.60
2021-02-08	124.44
2021-02-05	125.40
2021-02-04	123.77
2021-02-03	127.58
2021-02-02	127.54
2021-02-01	122.85
2021-01-29	125.15
2021-01-28	126.44
2021-01-27	123.31
2021-01-26	130.25
2021-01-25	132.87
2021-01-22	128.65
2021-01-21	127.65
2021-01-20	130.29
2021-01-19	127.15
2021-01-15	127.67
2021-01-14	127.81
2021-01-13	124.27
2021-01-12	123.23
2021-01-11	129.37
2021-01-08	127.17
2021-01-07	123.21
2021-01-06	117.06
2021-01-05	116.52
2021-01-04	118.29
2020-12-31	117.79
2020-12-30	119.17
2020-12-29	118.81
2020-12-28	122.77
2020-12-24	124.33
2020-12-23	125.56
2020-12-22	122.06
2020-12-21	115.29
2020-12-18	113.19
2020-12-17	106.65
2020-12-16	103.73
2020-12-15	107.26
2020-12-14	99.65
2020-12-11	95.44
2020-12-10	96.62
2020-12-09	97.19
2020-12-08	102.04
2020-12-07	104.81
2020-12-04	106.71
2020-12-03	106.19
2020-12-02	106.90
2020-12-01	106.50
2020-11-30	105.27
2020-11-27	106.52
2020-11-25	104.67
2020-11-24	104.25
2020-11-23	104.73
2020-11-20	102.37
2020-11-19	105.10
2020-11-18	105.58
2020-11-17	109.40
2020-11-16	108.65
2020-11-13	107.44
2020-11-12	102.60
2020-11-11	102.52
2020-11-10	104.54
2020-11-09	104.37
2020-11-06	101.31
2020-11-05	101.50
2020-11-04	54.10
2020-11-03	53.41
2020-11-02	53.15
2020-10-30	53.35
2020-10-29	53.24
2020-10-28	52.07
2020-10-27	53.39
2020-10-26	53.42
2020-10-23	53.80
2020-10-22	53.63
2020-10-21	52.68
2020-10-20	53.86
2020-10-19	53.64
2020-10-16	53.56
2020-10-15	54.88
2020-10-14	54.22
2020-10-13	54.51
2020-10-12	52.82
2020-10-09	52.20
2020-10-08	53.25
2020-10-07	52.75
2020-10-06	51.48
2020-10-05	54.07
2020-10-02	51.88
2020-10-01	54.27
2020-09-30	53.92
2020-09-29	55.09
2020-09-28	55.72
2020-09-25	55.34
2020-09-24	55.27
2020-09-23	56.06
2020-09-22	57.69
2020-09-21	57.05
2020-09-18	58.40
2020-09-17	58.28
2020-09-16	58.83
2020-09-15	60.15
2020-09-14	61.07
2020-09-11	59.06
2020-09-10	58.55
2020-09-09	60.40
2020-09-08	59.91
2020-09-04	63.19
2020-09-03	62.81
2020-09-02	62.57
2020-09-01	61.67
2020-08-31	61.93
2020-08-28	59.99
2020-08-27	59.78
2020-08-26	59.44
2020-08-25	60.11
2020-08-24	59.24
2020-08-21	59.85
2020-08-20	60.28
2020-08-19	59.41
2020-08-18	60.97
2020-08-17	61.35
2020-08-14	59.98
2020-08-13	60.33
2020-08-12	60.20
2020-08-11	60.70
2020-08-10	61.48
2020-08-07	63.88
2020-08-06	64.22
2020-08-05	52.12
2020-08-04	53.71
2020-08-03	53.67
2020-07-31	52.19
2020-07-30	53.51
2020-07-29	53.30
2020-07-28	53.87
2020-07-27	54.66
2020-07-24	53.45
2020-07-23	54.13
2020-07-22	55.01
2020-07-21	55.35
2020-07-20	56.28
2020-07-17	56.35
2020-07-16	56.39
2020-07-15	57.08
2020-07-14	55.76
2020-07-13	55.34
2020-07-10	56.30
2020-07-09	54.80
2020-07-08	55.23
2020-07-07	55.66
2020-07-06	55.10
2020-07-02	55.12
2020-07-01	54.58
2020-06-30	53.46
2020-06-29	53.86
2020-06-26	54.48
2020-06-25	55.35
2020-06-24	53.59
2020-06-23	52.43
2020-06-22	53.80
2020-06-19	53.45
2020-06-18	52.77
2020-06-17	52.27
2020-06-16	51.68
2020-06-15	51.87
2020-06-12	52.92
2020-06-11	51.24
2020-06-10	53.11
2020-06-09	53.02
2020-06-08	53.34
2020-06-05	52.19
2020-06-04	50.65
2020-06-03	51.52
2020-06-02	52.29
2020-06-01	51.54
2020-05-29	50.97
2020-05-28	51.17
2020-05-27	50.88
2020-05-26	50.81
2020-05-22	49.39
2020-05-21	49.23
2020-05-20	49.16
2020-05-19	48.51
2020-05-18	49.89
2020-05-15	48.12
2020-05-14	47.45
2020-05-13	49.35
2020-05-12	50.68
2020-05-11	50.94
2020-05-08	49.32
2020-05-07	48.29
2020-05-06	27.26
2020-05-05	27.85
2020-05-04	27.81
2020-05-01	26.69
2020-04-30	26.79
2020-04-29	27.43
2020-04-28	27.59
2020-04-27	28.16
2020-04-24	28.05
2020-04-23	27.48
2020-04-22	26.37
2020-04-21	25.75
2020-04-20	26.79
2020-04-17	26.57
2020-04-16	25.70
2020-04-15	24.51
2020-04-14	25.46
2020-04-13	24.72
2020-04-09	25.57
2020-04-08	25.33
2020-04-07	24.15
2020-04-06	24.83
2020-04-03	23.40
2020-04-02	23.64
2020-04-01	22.60
2020-03-31	22.81
2020-03-30	23.26
2020-03-27	23.84
2020-03-26	24.00
2020-03-25	22.55
2020-03-24	21.63
2020-03-23	20.07
2020-03-20	21.02
2020-03-19	22.22
2020-03-18	20.97
2020-03-17	21.47
2020-03-16	20.86
2020-03-13	23.35
2020-03-12	21.39
2020-03-11	23.71
2020-03-10	25.48
2020-03-09	24.76
2020-03-06	25.99
2020-03-05	25.53
2020-03-04	26.34
2020-03-03	24.47
2020-03-02	17.42
2020-02-28	16.91
2020-02-27	17.75
2020-02-26	18.66
2020-02-25	18.42
2020-02-24	19.01
2020-02-21	20.14
2020-02-20	20.41
2020-02-19	20.56
2020-02-18	20.50
2020-02-14	20.02
2020-02-13	20.00

DATE

PE RATIO

2021-02-24

117.10

2021-02-23

116.77

2021-02-22

116.54

2021-02-19

120.19

2021-02-18

119.85

2021-02-17

121.46

2021-02-16

117.08

2021-02-12

118.87

2021-02-11

120.73

2021-02-10

121.02

2021-02-09

123.60

2021-02-08

124.44

2021-02-05

125.40

2021-02-04

123.77

2021-02-03

127.58

2021-02-02

127.54

2021-02-01

122.85

2021-01-29

125.15

2021-01-28

126.44

2021-01-27

123.31

2021-01-26

130.25

2021-01-25

132.87

2021-01-22

128.65

2021-01-21

127.65

2021-01-20

130.29

2021-01-19

127.15

2021-01-15

127.67

2021-01-14

127.81

2021-01-13

124.27

2021-01-12

123.23

2021-01-11

129.37

2021-01-08

127.17

2021-01-07

123.21

2021-01-06

117.06

2021-01-05

116.52

2021-01-04

118.29

2020-12-31

117.79

2020-12-30

119.17

2020-12-29

118.81

2020-12-28

122.77

2020-12-24

124.33

2020-12-23

125.56

2020-12-22

122.06

2020-12-21

115.29

2020-12-18

113.19

2020-12-17

106.65

2020-12-16

103.73

2020-12-15

107.26

2020-12-14

99.65

2020-12-11

95.44

2020-12-10

96.62

2020-12-09

97.19

2020-12-08

102.04

2020-12-07

104.81

2020-12-04

106.71

2020-12-03

106.19

2020-12-02

106.90

2020-12-01

106.50

2020-11-30

105.27

2020-11-27

106.52

2020-11-25

104.67

2020-11-24

104.25

2020-11-23

104.73

2020-11-20

102.37

2020-11-19

105.10

2020-11-18

105.58

2020-11-17

109.40

2020-11-16

108.65

2020-11-13

107.44

2020-11-12

102.60

2020-11-11

102.52

2020-11-10

104.54

2020-11-09

104.37

2020-11-06

101.31

2020-11-05

101.50

2020-11-04

54.10

2020-11-03

53.41

2020-11-02

53.15

2020-10-30

53.35

2020-10-29

53.24

2020-10-28

52.07

2020-10-27

53.39

2020-10-26

53.42

2020-10-23

53.80

2020-10-22

53.63

2020-10-21

52.68

2020-10-20

53.86

2020-10-19

53.64

2020-10-16

53.56

2020-10-15

54.88

2020-10-14

54.22

2020-10-13

54.51

2020-10-12

52.82

2020-10-09

52.20

2020-10-08

53.25

2020-10-07

52.75

2020-10-06

51.48

2020-10-05

54.07

2020-10-02

51.88

2020-10-01

54.27

2020-09-30

53.92

2020-09-29

55.09

2020-09-28

55.72

2020-09-25

55.34

2020-09-24

55.27

2020-09-23

56.06

2020-09-22

57.69

2020-09-21

57.05

2020-09-18

58.40

2020-09-17

58.28

2020-09-16

58.83

2020-09-15

60.15

2020-09-14

61.07

2020-09-11

59.06

2020-09-10

58.55

2020-09-09

60.40

2020-09-08

59.91

2020-09-04

63.19

2020-09-03

62.81

2020-09-02

62.57

2020-09-01

61.67

2020-08-31

61.93

2020-08-28

59.99

2020-08-27

59.78

2020-08-26

59.44

2020-08-25

60.11

2020-08-24

59.24

2020-08-21

59.85

2020-08-20

60.28

2020-08-19

59.41

2020-08-18

60.97

2020-08-17

61.35

2020-08-14

59.98

2020-08-13

60.33

2020-08-12

60.20

2020-08-11

60.70

2020-08-10

61.48

2020-08-07

63.88

2020-08-06

64.22

2020-08-05

52.12

2020-08-04

53.71

2020-08-03

53.67

2020-07-31

52.19

2020-07-30

53.51

2020-07-29

53.30

2020-07-28

53.87

2020-07-27

54.66

2020-07-24

53.45

2020-07-23

54.13

2020-07-22

55.01

2020-07-21

55.35

2020-07-20

56.28

2020-07-17

56.35

2020-07-16

56.39

2020-07-15

57.08

2020-07-14

55.76

2020-07-13

55.34

2020-07-10

56.30

2020-07-09

54.80

2020-07-08

55.23

2020-07-07

55.66

2020-07-06

55.10

2020-07-02

55.12

2020-07-01

54.58

2020-06-30

53.46

2020-06-29

53.86

2020-06-26

54.48

2020-06-25

55.35

2020-06-24

53.59

2020-06-23

52.43

2020-06-22

53.80

2020-06-19

53.45

2020-06-18

52.77

2020-06-17

52.27

2020-06-16

51.68

2020-06-15

51.87

2020-06-12

52.92

2020-06-11

51.24

2020-06-10

53.11

2020-06-09

53.02

2020-06-08

53.34

2020-06-05

52.19

2020-06-04

50.65

2020-06-03

51.52

2020-06-02

52.29

2020-06-01

51.54

2020-05-29

50.97

2020-05-28

51.17

2020-05-27

50.88

2020-05-26

50.81

2020-05-22

49.39

2020-05-21

49.23

2020-05-20

49.16

2020-05-19

48.51

2020-05-18

49.89

2020-05-15

48.12

2020-05-14

47.45

2020-05-13

49.35

2020-05-12

50.68

2020-05-11

50.94

2020-05-08

49.32

2020-05-07

48.29

2020-05-06

27.26

2020-05-05

27.85

2020-05-04

27.81

2020-05-01

26.69

2020-04-30

26.79

2020-04-29

27.43

2020-04-28

27.59

2020-04-27

28.16

2020-04-24

28.05

2020-04-23

27.48

2020-04-22

26.37

2020-04-21

25.75

2020-04-20

26.79

2020-04-17

26.57

2020-04-16

25.70

2020-04-15

24.51

2020-04-14

25.46

2020-04-13

24.72

2020-04-09

25.57

2020-04-08

25.33

2020-04-07

24.15

2020-04-06

24.83

2020-04-03

23.40

2020-04-02

23.64

2020-04-01

22.60

2020-03-31

22.81

2020-03-30

23.26

2020-03-27

23.84

2020-03-26

24.00

2020-03-25

22.55

2020-03-24

21.63

2020-03-23

20.07

2020-03-20

21.02

2020-03-19

22.22

2020-03-18

20.97

2020-03-17

21.47

2020-03-16

20.86

2020-03-13

23.35

2020-03-12

21.39

2020-03-11

23.71

2020-03-10

25.48

2020-03-09

24.76

2020-03-06

25.99

2020-03-05

25.53

2020-03-04

26.34

2020-03-03

24.47

2020-03-02

17.42

2020-02-28

16.91

2020-02-27

17.75

2020-02-26

18.66

2020-02-25

18.42

2020-02-24

19.01

2020-02-21

20.14

2020-02-20

20.41

2020-02-19

20.56

2020-02-18

20.50

2020-02-14

20.02

2020-02-13

20.00

PE Ratio: N/A

IONS PE Ratio Chart

IONS Average PE Ratio Chart

IONS PE Ratio Metrics

IONS Competitors' PE Ratio

P/E Comparison

Forward P/E Calculation

PE Ratio Formula & Definition

PE Ratio FAQ

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