Chemed Corporation (CHE) vs Ionis Pharmaceuticals, Inc. (IONS)
A side-by-side comparison of Chemed Corporation and Ionis Pharmaceuticals, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
CHE
Chemed Corporation
$509.60HealthcareDelayed quote: Oct 6, 2026, 11:09 AM EDT
IONS
Ionis Pharmaceuticals, Inc.
$44.46HealthcareDelayed quote: Oct 6, 2026, 11:10 AM EDT
Total return — CHE vs IONS
growth of $100 · dividends reinvested · last 10yCHE +280.2% (+14.3%/yr)IONS +22.0% (+2.0%/yr)CHE compounded faster over this window
CHE IONS
CHE vs IONS: by the numbers
- •IONS is the larger company ($7.39B vs $6.66B market cap).
- •CHE is profitable (10.60% net margin) while IONS runs a net loss (-64.64%).
- •IONS grew revenue faster over the past five years (4.91% vs 4.12% CAGR).
- •CHE pays a dividend (0.49% yield), while IONS has no payments in the available dividend history.
Metrics side by side
Valuation
| Metric | CHE | IONS |
|---|---|---|
| P/E ratio | 25.58 | N/A |
| Forward P/E | 19.99 | N/A |
| P/S ratio | 2.57 | 8.46 |
| P/B ratio | 8.02 | 16.80 |
| EV / EBITDA | 16.72 | 2.23 |
| FCF yield | 4.86% | N/A |
Profitability
| Metric | CHE | IONS |
|---|---|---|
| Gross margin | 30.44% | 98.16% |
| Operating margin | 13.46% | -40.47% |
| Net margin | 10.60% | -64.64% |
| ROE | 33.11% | -128.44% |
| ROIC | 19.48% | -20.37% |
Dividends
| Metric | CHE | IONS |
|---|---|---|
| Dividend yield | 0.49% | N/A |
| Payout ratio | 12.55% | N/A |
Growth (annualized)
| Metric | CHE | IONS |
|---|---|---|
| Revenue CAGR (5Y) | 4.12% | 4.91% |
| EPS CAGR (5Y) | -1.65% | N/A |
| FCF CAGR (5Y) | -5.44% | N/A |
| Total return CAGR (5Y) | 3.58% | 5.82% |
Frequently asked
- Which has grown faster, CHE or IONS?
- Over the past five years, IONS grew revenue faster — CHE at a 4.12% CAGR versus IONS at 4.91%.
- Does CHE or IONS pay a bigger dividend?
- CHE pays a dividend (0.49% yield), while IONS has no payments in the available dividend history.
- Is CHE or IONS more profitable?
- CHE runs the higher net margin — CHE at 10.60% versus IONS at -64.64%.
- How have CHE and IONS total returns compared?
- Over the past 10 years, CHE delivered 14.19% and IONS delivered 1.80% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Chemed P/E ratioChemed dividend yieldChemed ROEIonis Pharmaceuticals ROEChemed operating marginIonis Pharmaceuticals operating marginChemed revenue growthIonis Pharmaceuticals revenue growthChemed free cash flowIonis Pharmaceuticals free cash flow
Chemed & Ionis Pharmaceuticals appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.