Ionis Pharmaceuticals (IONS) Interest Coverage Ratio: History & Chart

Ionis Pharmaceuticals, Inc.(IONS)

Biotechnology · Carlsbad, CA

$44.06+0.55 (+1.28%)

Delayed quote: Oct 6, 2026, 3:00 PM EDT

About Ionis Pharmaceuticals, Inc.

Founded in 1989 and headquartered in Carlsbad, California, Ionis Pharmaceuticals, Inc. is a biopharmaceutical company specializing in the discovery and development of RNA-targeted therapies within the United States. Its commercial portfolio includes three key medications: SPINRAZA, prescribed for spinal muscular atrophy (SMA) in both children and adults; TEGSEDI, an injectable treatment targeting polyneuropathy associated with hereditary transthyretin-mediated amyloidosis in adult patients; and WAYLIVRA, which addresses familial chylomicronemia syndrome and familial partial lipodystrophy. Ionis also maintains a robust pipeline, with several drug candidates currently in Phase 3 clinical trials. These include Eplontersen, a monthly self-administered subcutaneous injection designed for all forms of TTR amyloidosis; Olezarsen, intended for individuals with severe hypertriglyceridemia (SHTG); Donidalorsen, for patients suffering from hereditary angioedema; ION363, aimed at amyotrophic lateral sclerosis (ALS); Pelacarsen, developed for those with established cardiovascular disease and elevated lipoprotein(a); and Tofersen, which works by inhibiting the production of superoxide dismutase 1. Beyond these late-stage assets, the company is actively researching treatments for metabolic, infectious, renal, and ophthalmic diseases, as well as various types of cancer. The firm engages in significant collaborations, notably a strategic partnership with Biogen Inc. Additionally, it holds licensing and collaboration agreements with AstraZeneca, Bayer AG, GlaxoSmithKline plc, Novartis AG, Roche, Janssen Biotech, Inc., and Flamingo Therapeutics, Inc.

Carlsbad, CA

1,480 employees

www.ionis.com

Healthcare / Biotechnology

Sector: Healthcare
Industry: Biotechnology
CEO: Brett Monia

View full financials

IONS Interest Coverage Ratio Metrics

INTEREST COVERAGE RATIO

-4.22x

INTEREST COVERAGE RATIO AVG TTM

-4.08x

INTEREST COVERAGE RATIO AVG 3Y

-5.91x

INTEREST COVERAGE RATIO AVG 5Y

-12.02x

INTEREST COVERAGE RATIO AVG 10Y

-3.35x

INTEREST COVERAGE RATIO AVG 15Y

-3.08x

INTEREST COVERAGE RATIO AVG 20Y

-2.96x

CURRENT VS TTM AVG

-3.41%

CURRENT VS 3Y AVG

+28.64%

CURRENT VS 5Y AVG

+64.89%

CURRENT VS 10Y AVG

-25.80%

CURRENT VS 15Y AVG

-36.89%

CURRENT VS 20Y AVG

-42.57%

SECTOR MEDIAN · HEALTHCARE

-6.38x

median of 528 covered companies

CURRENT VS SECTOR MEDIAN

+33.80%

vs the sector median at left

NAME	MARKET CAP	INTEREST COVERAGE RATIO	TTM	3Y	5Y
Ionis Pharmaceuticals, Inc. (IONS)	$7.32B	-4.22x	-4.08x	-5.91x	-12.02x
Hinge Health, Inc. (HNGE)vs ›	$7.58B	N/A	N/A	N/A	N/A
HealthEquity, Inc. (HQY)vs ›	$7.61B	5.64x	4.71x	3.13x	2.65x
Cytokinetics, Incorporated (CYTK)vs ›	$7.62B	-5.89x	8.36x	8.36x	8.36x
Alkermes plc (ALKS)vs ›	$7.00B	20.69x	19.66x	19.10x	16.50x
Praxis Precision Medicines, Inc. (PRAX)vs ›	$7.72B	N/A	N/A	N/A	N/A
Caris Life Sciences, Inc. (CAI)vs ›	$7.78B	0.79x	0.79x	0.79x	1.52x
Chemed Corporation (CHE)vs ›	$6.65B	193.28x	199.58x	145.92x	155.47x
TG Therapeutics, Inc. (TGTX)vs ›	$8.04B	4.61x	3.18x	2.67x	2.67x
Immunovant, Inc. (IMVT)vs ›	$6.57B	N/A	N/A	N/A	N/A

NAME

MARKET CAP

INTEREST COVERAGE RATIO

TTM

Ionis Pharmaceuticals, Inc. (IONS)

$7.32B

-4.22x

-4.08x

-5.91x

-12.02x

Hinge Health, Inc. (HNGE)vs ›

$7.58B

N/A

HealthEquity, Inc. (HQY)vs ›

$7.61B

5.64x

4.71x

3.13x

2.65x

Cytokinetics, Incorporated (CYTK)vs ›

$7.62B

-5.89x

8.36x

Alkermes plc (ALKS)vs ›

$7.00B

20.69x

19.66x

19.10x

16.50x

Praxis Precision Medicines, Inc. (PRAX)vs ›

$7.72B

N/A

Caris Life Sciences, Inc. (CAI)vs ›

$7.78B

0.79x

1.52x

Chemed Corporation (CHE)vs ›

$6.65B

193.28x

199.58x

145.92x

155.47x

TG Therapeutics, Inc. (TGTX)vs ›

$8.04B

4.61x

3.18x

2.67x

Immunovant, Inc. (IMVT)vs ›

$6.57B

N/A

Interest Coverage Ratio FAQ

What is the interest coverage ratio for Ionis Pharmaceuticals, Inc. (IONS)?

The interest coverage ratio for IONS stock is -4.22x.

Is Ionis Pharmaceuticals, Inc.'s interest coverage ratio high or low?

The interest coverage ratio of -4.22x is 65% above its 5-year average of -12.02x, around the middle of its 5-year range (-120.17x–98.57x).

What is the TTM average interest coverage ratio for Ionis Pharmaceuticals, Inc. (IONS)?

The TTM average interest coverage ratio for IONS stock is -4.08x.

What is the 3Y average interest coverage ratio for Ionis Pharmaceuticals, Inc. (IONS)?

The 3Y average interest coverage ratio for IONS stock is -5.91x.

What is the 5Y average interest coverage ratio for Ionis Pharmaceuticals, Inc. (IONS)?

The 5Y average interest coverage ratio for IONS stock is -12.02x.

What is the 10Y average interest coverage ratio for Ionis Pharmaceuticals, Inc. (IONS)?

The 10Y average interest coverage ratio for IONS stock is -3.35x.

What is the 15Y average interest coverage ratio for Ionis Pharmaceuticals, Inc. (IONS)?

The 15Y average interest coverage ratio for IONS stock is -3.08x.

What is the 20Y average interest coverage ratio for Ionis Pharmaceuticals, Inc. (IONS)?

The 20Y average interest coverage ratio for IONS stock is -2.96x.

DATE	INTEREST COVERAGE RATIO
2026-06-30	-4.62x
2026-03-31	-5.22x
2025-12-31	-9.48x
2025-09-30	-7.23x
2025-06-30	6.14x
2025-03-31	-6.40x
2024-12-31	-4.85x
2024-09-30	-6.55x
2024-06-30	-2.90x
2024-03-31	-6.76x
2023-12-31	-0.27x
2023-09-30	-6.52x
2023-06-30	-4.52x
2023-03-31	-6.67x
2022-12-31	-120.17x
2022-09-30	-27.65x
2022-06-30	-40.15x
2022-03-31	-27.10x
2021-12-31	98.57x
2021-09-30	-36.69x
2021-06-30	-30.96x
2021-03-31	-38.10x
2020-12-31	-9.31x
2020-09-30	-15.05x
2020-06-30	-21.20x
2020-03-31	-27.70x
2019-12-31	19.50x
2019-09-30	0.21x
2019-06-30	-1.60x
2019-03-31	10.48x
2018-12-31	0.94x
2018-09-30	-1.65x
2018-06-30	-4.52x
2018-03-31	-0.30x
2017-12-31	-0.16x
2017-09-30	1.04x
2017-06-30	0.55x
2017-03-31	1.71x
2016-12-31	4.14x
2016-09-30	1.65x
2016-06-30	-5.08x
2016-03-31	-5.76x
2015-12-31	-6.73x
2015-09-30	-5.21x
2015-06-30	4.89x
2015-03-31	-1.03x
2014-12-31	1.38x
2014-09-30	-4.30x
2014-06-30	-1.34x
2014-03-31	-6.00x
2013-12-31	-4.07x
2013-09-30	-5.24x
2013-06-30	-1.65x
2013-03-31	0.34x
2012-09-30	-4.72x
2012-06-30	0.71x
2012-03-31	-3.56x
2011-12-31	-3.64x
2011-09-30	-4.68x
2011-06-30	-4.09x
2011-03-31	-4.72x
2010-12-31	-4.67x
2010-09-30	-2.68x
2010-06-30	-5.72x
2010-03-31	-1.51x
2009-12-31	-3.59x
2009-09-30	-3.26x
2009-06-30	-1.53x
2009-03-31	-0.21x
2008-09-30	0.06x
2008-06-30	0.37x
2008-03-31	-2.15x

DATE

INTEREST COVERAGE RATIO

2026-06-30

-4.62x

2026-03-31

-5.22x

2025-12-31

-9.48x

2025-09-30

-7.23x

2025-06-30

6.14x

2025-03-31

-6.40x

2024-12-31

-4.85x

2024-09-30

-6.55x

2024-06-30

-2.90x

2024-03-31

-6.76x

2023-12-31

-0.27x

2023-09-30

-6.52x

2023-06-30

-4.52x

2023-03-31

-6.67x

2022-12-31

-120.17x

2022-09-30

-27.65x

2022-06-30

-40.15x

2022-03-31

-27.10x

2021-12-31

98.57x

2021-09-30

-36.69x

2021-06-30

-30.96x

2021-03-31

-38.10x

2020-12-31

-9.31x

2020-09-30

-15.05x

2020-06-30

-21.20x

2020-03-31

-27.70x

2019-12-31

19.50x

2019-09-30

0.21x

2019-06-30

-1.60x

2019-03-31

10.48x

2018-12-31

0.94x

2018-09-30

-1.65x

2018-06-30

-4.52x

2018-03-31

-0.30x

2017-12-31

-0.16x

2017-09-30

1.04x

2017-06-30

0.55x

2017-03-31

1.71x

2016-12-31

4.14x

2016-09-30

1.65x

2016-06-30

-5.08x

2016-03-31

-5.76x

2015-12-31

-6.73x

2015-09-30

-5.21x

2015-06-30

4.89x

2015-03-31

-1.03x

2014-12-31

1.38x

2014-09-30

-4.30x

2014-06-30

-1.34x

2014-03-31

-6.00x

2013-12-31

-4.07x

2013-09-30

-5.24x

2013-06-30

-1.65x

2013-03-31

0.34x

2012-09-30

-4.72x

2012-06-30

0.71x

2012-03-31

-3.56x

2011-12-31

-3.64x

2011-09-30

-4.68x

2011-06-30

-4.09x

2011-03-31

-4.72x

2010-12-31

-4.67x

2010-09-30

-2.68x

2010-06-30

-5.72x

2010-03-31

-1.51x

2009-12-31

-3.59x

2009-09-30

-3.26x

2009-06-30

-1.53x

2009-03-31

-0.21x

2008-09-30

0.06x

2008-06-30

0.37x

2008-03-31

-2.15x

Interest Coverage Ratio: -4.22x

IONS Interest Coverage Ratio

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