Vertex Pharmaceuticals (VRTX) Price/FCF Ratio: History & Chart

Vertex Pharmaceuticals Incorporated(VRTX)

Biotechnology · Boston, MA

$524.11-4.79 (-0.91%)

Delayed quote: Sep 9, 2026, 10:20 AM EDT

About Vertex Pharmaceuticals Incorporated

Vertex Pharmaceuticals Incorporated is a leading biotechnology firm primarily focused on the discovery, advancement, and marketing of innovative treatments, particularly for cystic fibrosis (CF). The company offers a range of approved medications for CF patients, including SYMDEKO/SYMKEVI, ORKAMBI, and KALYDECO, which target specific mutations within the cystic fibrosis transmembrane conductance regulator gene. Additionally, they provide TRIKAFTA for individuals with CF aged six years and older who possess at least one F508del mutation. Beyond its established CF therapies, Vertex maintains a robust and diverse clinical pipeline. This includes VX-864, currently in Phase 2 for alpha-1 antitrypsin (AAT) deficiency; VX-147, also in Phase 2, addressing APOL1-mediated focal segmental glomerulosclerosis (FSGS) and other serious kidney conditions; VX-880, a potential treatment for Type 1 Diabetes undergoing Phase 1/2 trials; VX-548, a NaV1.8 inhibitor in Phase 2 for various forms of acute, neuropathic, and musculoskeletal pain; and CTX001, which is in Phase 3 development for severe sickle cell disease (SCD) and transfusion-dependent beta-thalassemia (TDT). The company distributes its pharmaceutical products through specialty pharmacies and distributors across the United States, while international sales are facilitated via a network of specialty distributors, retail chains, hospitals, and clinics. Vertex also engages in numerous strategic collaborations with partners such as Affinia Therapeutics, Arbor Biotechnologies, CRISPR Therapeutics, Kymera Therapeutics, Mammoth Biosciences, Moderna, Obsidian Therapeutics, Skyhawk Therapeutics, Ribometrix, Genomics plc, Merck KGaA, and X-Chem. Established in 1989, Vertex Pharmaceuticals is headquartered in Boston, Massachusetts.

Boston, MA

6,400 employees

www.vrtx.com

Healthcare / Biotechnology

Sector: Healthcare
Industry: Biotechnology
CEO: Reshma Kewalramani

View full financials

VRTX Price/FCF Ratio Metrics

PRICE/FCF RATIO

35.63

PRICE/FCF RATIO AVG TTM

33.75

PRICE/FCF RATIO AVG 3Y

31.40

PRICE/FCF RATIO AVG 5Y

27.88

PRICE/FCF RATIO AVG 10Y

34.93

PRICE/FCF RATIO AVG 15Y

35.03

PRICE/FCF RATIO AVG 20Y

N/A

CURRENT VS TTM AVG

+5.58%

CURRENT VS 3Y AVG

+13.49%

CURRENT VS 5Y AVG

+27.82%

CURRENT VS 10Y AVG

+2.00%

CURRENT VS 15Y AVG

+1.72%

CURRENT VS 20Y AVG

N/A

SECTOR MEDIAN · HEALTHCARE

21.55

median of 83 covered companies

CURRENT VS SECTOR MEDIAN

+65.34%

vs the sector median at left

NAME	MARKET CAP	PRICE/FCF RATIO	TTM	3Y	5Y
Vertex Pharmaceuticals Incorporated (VRTX)	$133.02B	35.63	33.75	31.40	27.88
Bristol-Myers Squibb Company (BMY)vs ›	$132.54B	11.58	8.66	8.33	9.50
Intuitive Surgical, Inc. (ISRG)vs ›	$125.41B	38.95	68.47	158.53	125.73
Danaher Corporation (DHR)vs ›	$142.71B	26.57	28.14	29.98	27.87
CVS Health Corp. (CVS)vs ›	$120.12B	10.48	15.60	15.06	12.06
Medtronic plc (MDT)vs ›	$119.29B	19.36	21.87	22.16	22.97
Pfizer Inc. (PFE)vs ›	$158.87B	14.42	14.52	19.53	15.97
Stryker Corporation (SYK)vs ›	$105.46B	22.69	31.24	39.73	40.22
McKesson Corporation (MCK)vs ›	$104.51B	17.14	15.82	20.43	16.84
Sanofi (SNY)vs ›	$103.96B	7.56	7.74	7.74	7.74

NAME

MARKET CAP

PRICE/FCF RATIO

TTM

Vertex Pharmaceuticals Incorporated (VRTX)

$133.02B

35.63

33.75

31.40

27.88

Bristol-Myers Squibb Company (BMY)vs ›

$132.54B

11.58

8.66

8.33

9.50

Intuitive Surgical, Inc. (ISRG)vs ›

$125.41B

38.95

68.47

158.53

125.73

Danaher Corporation (DHR)vs ›

$142.71B

26.57

28.14

29.98

27.87

CVS Health Corp. (CVS)vs ›

$120.12B

10.48

15.60

15.06

12.06

Medtronic plc (MDT)vs ›

$119.29B

19.36

21.87

22.16

22.97

Pfizer Inc. (PFE)vs ›

$158.87B

14.42

14.52

19.53

15.97

Stryker Corporation (SYK)vs ›

$105.46B

22.69

31.24

39.73

40.22

McKesson Corporation (MCK)vs ›

$104.51B

17.14

15.82

20.43

16.84

Sanofi (SNY)vs ›

$103.96B

7.56

7.74

Price/FCF Ratio FAQ

What is the Price/FCF ratio for Vertex Pharmaceuticals Incorporated (VRTX)?

The Price/FCF ratio for VRTX stock is 35.63.

Is Vertex Pharmaceuticals Incorporated's Price/FCF ratio high or low?

The Price/FCF ratio of 35.63 is 28% above its 5-year average of 27.88, near the high end of its 5-year range (18.91–40.03).

What is the TTM average Price/FCF ratio for Vertex Pharmaceuticals Incorporated (VRTX)?

The TTM average Price/FCF ratio for VRTX stock is 33.75.

What is the 3Y average Price/FCF ratio for Vertex Pharmaceuticals Incorporated (VRTX)?

The 3Y average Price/FCF ratio for VRTX stock is 31.40.

What is the 5Y average Price/FCF ratio for Vertex Pharmaceuticals Incorporated (VRTX)?

The 5Y average Price/FCF ratio for VRTX stock is 27.88.

What is the 10Y average Price/FCF ratio for Vertex Pharmaceuticals Incorporated (VRTX)?

The 10Y average Price/FCF ratio for VRTX stock is 34.93.

What is the 15Y average Price/FCF ratio for Vertex Pharmaceuticals Incorporated (VRTX)?

The 15Y average Price/FCF ratio for VRTX stock is 35.03.

DATE	PRICE/FCF RATIO
2026-09-08	35.63
2026-09-04	36.79
2026-09-03	37.58
2026-09-02	37.50
2026-09-01	36.89
2026-08-31	36.68
2026-08-28	36.49
2026-08-27	36.88
2026-08-26	36.86
2026-08-25	37.24
2026-08-24	36.88
2026-08-21	36.92
2026-08-20	36.39
2026-08-19	37.19
2026-08-18	35.58
2026-08-17	34.73
2026-08-14	34.07
2026-08-13	34.79
2026-08-12	35.41
2026-08-11	35.68
2026-08-10	35.29
2026-08-07	33.41
2026-08-06	32.60
2026-08-05	32.66
2026-08-04	32.25
2026-08-03	32.52
2026-07-31	32.96
2026-07-30	33.27
2026-07-29	33.39
2026-07-28	33.88
2026-07-27	33.09
2026-07-24	32.98
2026-07-23	32.68
2026-07-22	32.64
2026-07-21	33.30
2026-07-20	33.19
2026-07-17	33.55
2026-07-16	33.57
2026-07-15	32.96
2026-07-14	32.90
2026-07-13	33.17
2026-07-10	33.53
2026-07-09	34.30
2026-07-08	34.43
2026-07-07	36.08
2026-07-06	36.58
2026-07-02	36.48
2026-07-01	34.40
2026-06-30	34.31
2026-06-29	34.51
2026-06-26	33.94
2026-06-25	33.17
2026-06-24	32.83
2026-06-23	32.36
2026-06-22	32.24
2026-06-18	31.20
2026-06-17	31.71
2026-06-16	31.30
2026-06-15	31.12
2026-06-12	30.73
2026-06-11	30.74
2026-06-10	30.10
2026-06-09	30.79
2026-06-08	30.60
2026-06-05	30.87
2026-06-04	30.51
2026-06-03	29.59
2026-06-02	29.36
2026-06-01	30.28
2026-05-29	30.92
2026-05-28	30.94
2026-05-27	30.20
2026-05-26	30.11
2026-05-22	30.02
2026-05-21	29.95
2026-05-20	29.73
2026-05-19	30.00
2026-05-18	30.16
2026-05-15	30.18
2026-05-14	31.11
2026-05-13	31.30
2026-05-12	30.97
2026-05-11	30.06
2026-05-08	29.69
2026-05-07	29.36
2026-05-06	29.54
2026-05-05	29.31
2026-05-04	34.47
2026-05-01	33.99
2026-04-30	34.27
2026-04-29	33.94
2026-04-28	34.49
2026-04-27	34.16
2026-04-24	34.50
2026-04-23	34.89
2026-04-22	35.10
2026-04-21	35.01
2026-04-20	35.22
2026-04-17	35.38
2026-04-16	34.93
2026-04-15	35.42
2026-04-14	35.63
2026-04-13	35.29
2026-04-10	34.98
2026-04-09	35.83
2026-04-08	35.60
2026-04-07	34.63
2026-04-06	34.83
2026-04-02	35.18
2026-04-01	35.86
2026-03-31	35.81
2026-03-30	35.54
2026-03-27	34.73
2026-03-26	36.38
2026-03-25	36.48
2026-03-24	35.97
2026-03-23	36.18
2026-03-20	36.40
2026-03-19	36.73
2026-03-18	36.21
2026-03-17	37.09
2026-03-16	37.37
2026-03-13	37.63
2026-03-12	38.34
2026-03-11	39.48
2026-03-10	40.03
2026-03-09	36.96
2026-03-06	36.62
2026-03-05	36.95
2026-03-04	38.32
2026-03-03	38.03
2026-03-02	38.97
2026-02-27	39.84
2026-02-26	38.50
2026-02-25	38.73
2026-02-24	39.09
2026-02-23	38.57
2026-02-20	38.24
2026-02-19	37.63
2026-02-18	37.71
2026-02-17	38.27
2026-02-13	39.41
2026-02-12	35.90
2026-02-11	35.60
2026-02-10	35.78
2026-02-09	36.35
2026-02-06	36.89
2026-02-05	35.42
2026-02-04	36.32
2026-02-03	35.94
2026-02-02	36.43
2026-01-30	36.27
2026-01-29	36.72
2026-01-28	36.89
2026-01-27	36.60
2026-01-26	36.81
2026-01-23	36.16
2026-01-22	36.07
2026-01-21	35.60
2026-01-20	34.12
2026-01-16	34.07
2026-01-15	33.88
2026-01-14	34.70
2026-01-13	35.10
2026-01-12	35.55
2026-01-09	35.81
2026-01-08	36.25
2026-01-07	37.37
2026-01-06	36.15
2026-01-05	34.64
2026-01-02	34.90
2025-12-31	35.00
2025-12-30	35.02
2025-12-29	35.49
2025-12-26	35.73
2025-12-24	35.74
2025-12-23	35.45
2025-12-22	35.53
2025-12-19	35.21
2025-12-18	34.53
2025-12-17	34.70
2025-12-16	35.12
2025-12-15	35.18
2025-12-12	34.89
2025-12-11	34.42
2025-12-10	34.32
2025-12-09	33.73
2025-12-08	34.12
2025-12-05	35.16
2025-12-04	35.30
2025-12-03	35.75
2025-12-02	33.44
2025-12-01	32.85
2025-11-28	33.47
2025-11-26	33.36
2025-11-25	33.18
2025-11-24	32.73
2025-11-21	32.94
2025-11-20	32.60
2025-11-19	32.50
2025-11-18	33.62
2025-11-17	33.50
2025-11-14	33.74
2025-11-13	33.54
2025-11-12	33.52
2025-11-11	33.13
2025-11-10	32.51
2025-11-07	31.61
2025-11-06	32.13
2025-11-05	32.19
2025-11-04	32.55
2025-11-03	31.51
2025-10-31	31.48
2025-10-30	31.06
2025-10-29	30.86
2025-10-28	31.25
2025-10-27	31.08
2025-10-24	31.17
2025-10-23	31.27
2025-10-22	31.55
2025-10-21	31.53
2025-10-20	31.00
2025-10-17	30.83
2025-10-16	30.23
2025-10-15	30.18
2025-10-14	30.50
2025-10-13	30.14
2025-10-10	30.17
2025-10-09	30.69
2025-10-08	31.16
2025-10-07	30.35
2025-10-06	29.81
2025-10-03	29.84
2025-10-02	30.25
2025-10-01	29.90
2025-09-30	28.97
2025-09-29	29.24
2025-09-26	28.54
2025-09-25	28.25
2025-09-24	27.86
2025-09-23	28.09
2025-09-22	28.34
2025-09-19	28.34
2025-09-18	28.64
2025-09-17	28.64
2025-09-16	28.95
2025-09-15	29.09
2025-09-12	29.19
2025-09-11	29.40
2025-09-10	28.74
2025-09-09	29.33
2025-09-08	29.24
2025-09-05	29.30
2025-09-04	29.36
2025-09-03	29.34
2025-09-02	29.67
2025-08-29	28.93
2025-08-28	29.00
2025-08-27	28.78
2025-08-26	28.64

DATE

PRICE/FCF RATIO

2026-09-08

35.63

2026-09-04

36.79

2026-09-03

37.58

2026-09-02

37.50

2026-09-01

36.89

2026-08-31

36.68

2026-08-28

36.49

2026-08-27

36.88

2026-08-26

36.86

2026-08-25

37.24

2026-08-24

36.88

2026-08-21

36.92

2026-08-20

36.39

2026-08-19

37.19

2026-08-18

35.58

2026-08-17

34.73

2026-08-14

34.07

2026-08-13

34.79

2026-08-12

35.41

2026-08-11

35.68

2026-08-10

35.29

2026-08-07

33.41

2026-08-06

32.60

2026-08-05

32.66

2026-08-04

32.25

2026-08-03

32.52

2026-07-31

32.96

2026-07-30

33.27

2026-07-29

33.39

2026-07-28

33.88

2026-07-27

33.09

2026-07-24

32.98

2026-07-23

32.68

2026-07-22

32.64

2026-07-21

33.30

2026-07-20

33.19

2026-07-17

33.55

2026-07-16

33.57

2026-07-15

32.96

2026-07-14

32.90

2026-07-13

33.17

2026-07-10

33.53

2026-07-09

34.30

2026-07-08

34.43

2026-07-07

36.08

2026-07-06

36.58

2026-07-02

36.48

2026-07-01

34.40

2026-06-30

34.31

2026-06-29

34.51

2026-06-26

33.94

2026-06-25

33.17

2026-06-24

32.83

2026-06-23

32.36

2026-06-22

32.24

2026-06-18

31.20

2026-06-17

31.71

2026-06-16

31.30

2026-06-15

31.12

2026-06-12

30.73

2026-06-11

30.74

2026-06-10

30.10

2026-06-09

30.79

2026-06-08

30.60

2026-06-05

30.87

2026-06-04

30.51

2026-06-03

29.59

2026-06-02

29.36

2026-06-01

30.28

2026-05-29

30.92

2026-05-28

30.94

2026-05-27

30.20

2026-05-26

30.11

2026-05-22

30.02

2026-05-21

29.95

2026-05-20

29.73

2026-05-19

30.00

2026-05-18

30.16

2026-05-15

30.18

2026-05-14

31.11

2026-05-13

31.30

2026-05-12

30.97

2026-05-11

30.06

2026-05-08

29.69

2026-05-07

29.36

2026-05-06

29.54

2026-05-05

29.31

2026-05-04

34.47

2026-05-01

33.99

2026-04-30

34.27

2026-04-29

33.94

2026-04-28

34.49

2026-04-27

34.16

2026-04-24

34.50

2026-04-23

34.89

2026-04-22

35.10

2026-04-21

35.01

2026-04-20

35.22

2026-04-17

35.38

2026-04-16

34.93

2026-04-15

35.42

2026-04-14

35.63

2026-04-13

35.29

2026-04-10

34.98

2026-04-09

35.83

2026-04-08

35.60

2026-04-07

34.63

2026-04-06

34.83

2026-04-02

35.18

2026-04-01

35.86

2026-03-31

35.81

2026-03-30

35.54

2026-03-27

34.73

2026-03-26

36.38

2026-03-25

36.48

2026-03-24

35.97

2026-03-23

36.18

2026-03-20

36.40

2026-03-19

36.73

2026-03-18

36.21

2026-03-17

37.09

2026-03-16

37.37

2026-03-13

37.63

2026-03-12

38.34

2026-03-11

39.48

2026-03-10

40.03

2026-03-09

36.96

2026-03-06

36.62

2026-03-05

36.95

2026-03-04

38.32

2026-03-03

38.03

2026-03-02

38.97

2026-02-27

39.84

2026-02-26

38.50

2026-02-25

38.73

2026-02-24

39.09

2026-02-23

38.57

2026-02-20

38.24

2026-02-19

37.63

2026-02-18

37.71

2026-02-17

38.27

2026-02-13

39.41

2026-02-12

35.90

2026-02-11

35.60

2026-02-10

35.78

2026-02-09

36.35

2026-02-06

36.89

2026-02-05

35.42

2026-02-04

36.32

2026-02-03

35.94

2026-02-02

36.43

2026-01-30

36.27

2026-01-29

36.72

2026-01-28

36.89

2026-01-27

36.60

2026-01-26

36.81

2026-01-23

36.16

2026-01-22

36.07

2026-01-21

35.60

2026-01-20

34.12

2026-01-16

34.07

2026-01-15

33.88

2026-01-14

34.70

2026-01-13

35.10

2026-01-12

35.55

2026-01-09

35.81

2026-01-08

36.25

2026-01-07

37.37

2026-01-06

36.15

2026-01-05

34.64

2026-01-02

34.90

2025-12-31

35.00

2025-12-30

35.02

2025-12-29

35.49

2025-12-26

35.73

2025-12-24

35.74

2025-12-23

35.45

2025-12-22

35.53

2025-12-19

35.21

2025-12-18

34.53

2025-12-17

34.70

2025-12-16

35.12

2025-12-15

35.18

2025-12-12

34.89

2025-12-11

34.42

2025-12-10

34.32

2025-12-09

33.73

2025-12-08

34.12

2025-12-05

35.16

2025-12-04

35.30

2025-12-03

35.75

2025-12-02

33.44

2025-12-01

32.85

2025-11-28

33.47

2025-11-26

33.36

2025-11-25

33.18

2025-11-24

32.73

2025-11-21

32.94

2025-11-20

32.60

2025-11-19

32.50

2025-11-18

33.62

2025-11-17

33.50

2025-11-14

33.74

2025-11-13

33.54

2025-11-12

33.52

2025-11-11

33.13

2025-11-10

32.51

2025-11-07

31.61

2025-11-06

32.13

2025-11-05

32.19

2025-11-04

32.55

2025-11-03

31.51

2025-10-31

31.48

2025-10-30

31.06

2025-10-29

30.86

2025-10-28

31.25

2025-10-27

31.08

2025-10-24

31.17

2025-10-23

31.27

2025-10-22

31.55

2025-10-21

31.53

2025-10-20

31.00

2025-10-17

30.83

2025-10-16

30.23

2025-10-15

30.18

2025-10-14

30.50

2025-10-13

30.14

2025-10-10

30.17

2025-10-09

30.69

2025-10-08

31.16

2025-10-07

30.35

2025-10-06

29.81

2025-10-03

29.84

2025-10-02

30.25

2025-10-01

29.90

2025-09-30

28.97

2025-09-29

29.24

2025-09-26

28.54

2025-09-25

28.25

2025-09-24

27.86

2025-09-23

28.09

2025-09-22

28.34

2025-09-19

28.34

2025-09-18

28.64

2025-09-17

28.64

2025-09-16

28.95

2025-09-15

29.09

2025-09-12

29.19

2025-09-11

29.40

2025-09-10

28.74

2025-09-09

29.33

2025-09-08

29.24

2025-09-05

29.30

2025-09-04

29.36

2025-09-03

29.34

2025-09-02

29.67

2025-08-29

28.93

2025-08-28

29.00

2025-08-27

28.78

2025-08-26

28.64

Price/FCF Ratio: 35.63

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