Vertex Pharmaceuticals Incorporated (VRTX) Operating Margin: 39.43%
Is Vertex Pharmaceuticals Incorporated’s operating margin high or low?
Vertex Pharmaceuticals Incorporated's operating margin of 39.43% is 14% above its 5-year average of 34.52%, near the high end of its 5-year range (-2.11%–48.23%).
The operating margin for Vertex Pharmaceuticals Incorporated (VRTX) is 39.43% as of Tuesday, June 9, 2026. It is above its 12-month average by 111.31% (18.66%).
VRTX Operating Margin Chart
VRTX Average Operating Margin Chart
VRTX Current vs Average Operating Margin Chart
VRTX Operating Margin Metrics
OPERATING MARGIN
39.43%
OPERATING MARGIN AVG TTM
18.66%
OPERATING MARGIN AVG 3Y
31.09%
OPERATING MARGIN AVG 5Y
34.52%
OPERATING MARGIN AVG 10Y
19.72%
OPERATING MARGIN AVG 15Y
-28.39%
OPERATING MARGIN AVG 20Y
-82.33%
CURRENT VS TTM AVG
+111.31%
CURRENT VS 3Y AVG
+26.80%
CURRENT VS 5Y AVG
+14.21%
CURRENT VS 10Y AVG
+99.99%
CURRENT VS 15Y AVG
+238.88%
CURRENT VS 20Y AVG
+147.89%
VRTX Competitors' Operating Margin
| NAME | MARKET CAP | OPERATING MARGIN | TTM | 3Y | 5Y |
|---|---|---|---|---|---|
| Vertex Pharmaceuticals Incorporated (VRTX) | — | 39.43% | 18.66% | 31.09% | 34.52% |
| Bristol-Myers Squibb Company (BMY) | $115.34B | 26.34% | 23.17% | 21.31% | 19.39% |
| Medtronic plc (MDT) | $105.25B | 17.78% | 17.77% | 17.25% | 17.00% |
| CVS Health Corporation (CVS) | $123.84B | 2.58% | 2.43% | 2.79% | 3.48% |
| Danaher Corporation (DHR) | $133.37B | 20.91% | 21.31% | 23.25% | 23.28% |
| Elevance Health Inc. (ELV) | $92.17B | 4.07% | 4.55% | 4.90% | 5.40% |
| Pfizer Inc. (PFE) | $146.48B | 24.67% | 25.29% | 24.23% | 24.05% |
| Cigna Corporation (CI) | $78.04B | 3.32% | 3.56% | 4.04% | 4.30% |
| Intuitive Surgical, Inc. (ISRG) | $151.09B | 29.27% | 28.70% | 26.89% | 27.25% |
| Gilead Sciences, Inc. (GILD) | $155.82B | 39.74% | 22.76% | 25.11% | 25.54% |
Operating Efficiency
Gross Margin
85.0%
Operating Margin
39.4%
Vertex Pharmaceuticals Incorporated Operating Margin Formula & Definition
Operating Margin = Operating Income / Revenue
Operating margin is the percentage of revenue remaining after operating expenses, reflecting operating efficiency.
Expanded definitions: Investopedia, Wikipedia, Corporate Finance Institute
Vertex Pharmaceuticals Incorporated Operating Margin FAQ
- What is the operating margin for Vertex Pharmaceuticals Incorporated (VRTX)?
- The operating margin for VRTX stock is 39.43%.
- Is Vertex Pharmaceuticals Incorporated's operating margin high or low?
- Vertex Pharmaceuticals Incorporated's operating margin of 39.43% is 14% above its 5-year average of 34.52%, near the high end of its 5-year range (-2.11%–48.23%).
- What is the TTM average operating margin for Vertex Pharmaceuticals Incorporated (VRTX)?
- The TTM average operating margin for VRTX stock is 18.66%.
- What is the 3Y average operating margin for Vertex Pharmaceuticals Incorporated (VRTX)?
- The 3Y average operating margin for VRTX stock is 31.09%.
- What is the 5Y average operating margin for Vertex Pharmaceuticals Incorporated (VRTX)?
- The 5Y average operating margin for VRTX stock is 34.52%.
- What is the 10Y average operating margin for Vertex Pharmaceuticals Incorporated (VRTX)?
- The 10Y average operating margin for VRTX stock is 19.72%.
- What is the 15Y average operating margin for Vertex Pharmaceuticals Incorporated (VRTX)?
- The 15Y average operating margin for VRTX stock is -28.39%.
- What is the 20Y average operating margin for Vertex Pharmaceuticals Incorporated (VRTX)?
- The 20Y average operating margin for VRTX stock is -82.33%.
Vertex Pharmaceuticals Incorporated Operating Margin History
| DATE | OPERATING MARGIN |
|---|---|
| 2025-12-31 | 39.43% |
| 2024-12-31 | -2.11% |
| 2023-12-31 | 38.83% |
| 2022-12-31 | 48.23% |
| 2021-12-31 | 36.73% |
| 2020-12-31 | 46.03% |
| 2019-12-31 | 28.77% |
| 2018-12-31 | 20.84% |
| 2017-12-31 | 4.95% |
| 2016-12-31 | 0.58% |
| 2015-12-31 | -45.40% |
| 2014-12-31 | -119.30% |
| 2013-12-31 | -74.54% |
| 2012-12-31 | 0.15% |
| 2011-12-31 | 8.07% |
| 2010-12-31 | -485.51% |
| 2009-12-31 | -601.10% |
| 2008-12-31 | -263.65% |
| 2007-12-31 | -210.94% |
| 2006-12-31 | -105.86% |
| 2005-12-31 | -93.15% |
| 2004-12-31 | -150.71% |
| 2003-12-31 | -382.59% |
| 2002-12-31 | -74.25% |
| 2001-12-31 | -54.81% |
| 2000-12-31 | -49.51% |
| 1999-12-31 | -64.29% |
| 1998-12-31 | -72.97% |
| 1997-12-31 | -43.84% |
| 1996-12-31 | -224.06% |