Which has the lower trailing P/E, DHR or VRTX?

VRTX has the lower trailing P/E: DHR trades at 35.53 and VRTX at 30.00. P/E is one valuation measure and does not by itself establish which business is cheaper.

Which has grown faster, DHR or VRTX?

Over the past five years, VRTX grew revenue faster — DHR at a 1.97% CAGR versus VRTX at 13.57%.

Does DHR or VRTX pay a bigger dividend?

DHR pays a dividend (0.72% yield), while VRTX has no payments in the available dividend history.

Is DHR or VRTX more profitable?

VRTX runs the higher net margin — DHR at 15.95% versus VRTX at 34.89%.

How have DHR and VRTX total returns compared?

Over the past 10 years, DHR delivered 11.94% and VRTX delivered 18.72% annualized total return. Past performance doesn't predict future results.

Danaher Corporation (DHR) vs Vertex Pharmaceuticals Incorporated (VRTX)

A side-by-side comparison of Danaher Corporation and Vertex Pharmaceuticals Incorporated across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of September 11, 2026. Differences are shown without an overall score or investment verdict.

DHR

Danaher Corporation

$140.64B

$200.06HealthcareDelayed quote: Sep 11, 2026, 4:00 PM EDT

VRTX

Vertex Pharmaceuticals Incorporated

$130.82B

$515.44HealthcareDelayed quote: Sep 11, 2026, 4:00 PM EDT

Total return — DHR vs VRTX

growth of $100 · dividends reinvested · last 10y

DHR +208.4% (+11.9%/yr)VRTX +462.1% (+18.8%/yr)VRTX compounded faster over this window

DHR VRTX

DHR vs VRTX: by the numbers

•DHR is the larger company ($140.64B vs $130.82B market cap).
•VRTX trades at the lower trailing earnings multiple (30.00 vs 35.53 P/E), one valuation lens rather than an overall verdict.
•VRTX converts more revenue to profit (34.89% vs 15.95% net margin).
•VRTX grew revenue faster over the past five years (13.57% vs 1.97% CAGR).
•DHR pays a dividend (0.72% yield), while VRTX has no payments in the available dividend history.

Metrics side by side

Valuation

Metric	DHR	VRTX
P/E ratio	35.53	30.00
Forward P/E	23.52	27.49
P/S ratio	5.60	10.36
P/B ratio	2.67	6.46
EV / EBITDA	22.54	24.88
FCF yield	3.89%	2.90%

Profitability

Metric	DHR	VRTX
Gross margin	58.51%	86.04%
Operating margin	20.42%	38.59%
Net margin	15.95%	34.89%
ROE	7.61%	21.76%
ROIC	5.03%	17.33%

Dividends

Metric	DHR	VRTX
Dividend yield	0.72%	N/A
Payout ratio	25.58%	N/A

Growth (annualized)

Metric	DHR	VRTX
Revenue CAGR (5Y)	1.97%	13.57%
EPS CAGR (5Y)	0.40%	8.17%
FCF CAGR (5Y)	-2.83%	16.39%
Total return CAGR (5Y)	-6.82%	22.61%

Frequently asked

Which has the lower trailing P/E, DHR or VRTX?: VRTX has the lower trailing P/E: DHR trades at 35.53 and VRTX at 30.00. P/E is one valuation measure and does not by itself establish which business is cheaper.
Which has grown faster, DHR or VRTX?: Over the past five years, VRTX grew revenue faster — DHR at a 1.97% CAGR versus VRTX at 13.57%.
Does DHR or VRTX pay a bigger dividend?: DHR pays a dividend (0.72% yield), while VRTX has no payments in the available dividend history.
Is DHR or VRTX more profitable?: VRTX runs the higher net margin — DHR at 15.95% versus VRTX at 34.89%.
How have DHR and VRTX total returns compared?: Over the past 10 years, DHR delivered 11.94% and VRTX delivered 18.72% annualized total return. Past performance doesn't predict future results.

Go deeper

Full DHR analysis Full VRTX analysis Interactive comparison tool

Dig into the metrics

Danaher P/E ratio Vertex Pharmaceuticals P/E ratio Danaher dividend yield Danaher ROE Vertex Pharmaceuticals ROE Danaher operating margin Vertex Pharmaceuticals operating margin Danaher revenue growth Vertex Pharmaceuticals revenue growth Danaher free cash flow Vertex Pharmaceuticals free cash flow

Danaher & Vertex Pharmaceuticals appear in these rankings

Highest Operating Margin Stocks Highest 10-Year Total Return Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified September 11, 2026.