Which has the lower trailing P/E, CVS or VRTX?

CVS has the lower trailing P/E: CVS trades at 25.04 and VRTX at 30.00. P/E is one valuation measure and does not by itself establish which business is cheaper.

Which has grown faster, CVS or VRTX?

Over the past five years, VRTX grew revenue faster — CVS at a 8.32% CAGR versus VRTX at 13.57%.

Does CVS or VRTX pay a bigger dividend?

CVS pays a dividend (2.79% yield), while VRTX has no payments in the available dividend history.

Is CVS or VRTX more profitable?

VRTX runs the higher net margin — CVS at 1.18% versus VRTX at 34.89%.

How have CVS and VRTX total returns compared?

Over the past 10 years, CVS delivered 3.54% and VRTX delivered 18.72% annualized total return. Past performance doesn't predict future results.

CVS Health Corp. (CVS) vs Vertex Pharmaceuticals Incorporated (VRTX)

A side-by-side comparison of CVS Health Corp. and Vertex Pharmaceuticals Incorporated across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of September 11, 2026. Differences are shown without an overall score or investment verdict.

CVS

CVS Health Corp.

$120.78B

$94.66HealthcareDelayed quote: Sep 11, 2026, 4:00 PM EDT

VRTX

Vertex Pharmaceuticals Incorporated

$130.82B

$515.44HealthcareDelayed quote: Sep 11, 2026, 4:00 PM EDT

Total return — CVS vs VRTX

growth of $100 · dividends reinvested · last 10y

CVS +40.4% (+3.5%/yr)VRTX +462.1% (+18.8%/yr)VRTX compounded faster over this window

CVS VRTX

CVS vs VRTX: by the numbers

•VRTX is the larger company ($130.82B vs $120.78B market cap).
•CVS trades at the lower trailing earnings multiple (25.04 vs 30.00 P/E), one valuation lens rather than an overall verdict.
•VRTX converts more revenue to profit (34.89% vs 1.18% net margin).
•VRTX grew revenue faster over the past five years (13.57% vs 8.32% CAGR).
•CVS pays a dividend (2.79% yield), while VRTX has no payments in the available dividend history.

Metrics side by side

Valuation

Metric	CVS	VRTX
P/E ratio	25.04	30.00
Forward P/E	11.83	27.49
P/S ratio	0.29	10.36
P/B ratio	1.52	6.46
EV / EBITDA	14.50	24.88
FCF yield	9.74%	2.90%

Profitability

Metric	CVS	VRTX
Gross margin	14.15%	86.04%
Operating margin	2.00%	38.59%
Net margin	1.18%	34.89%
ROE	6.16%	21.76%
ROIC	4.14%	17.33%

Dividends

Metric	CVS	VRTX
Dividend yield	2.79%	N/A
Payout ratio	70.37%	N/A

Growth (annualized)

Metric	CVS	VRTX
Revenue CAGR (5Y)	8.32%	13.57%
EPS CAGR (5Y)	-23.89%	8.17%
FCF CAGR (5Y)	-10.28%	16.39%
Total return CAGR (5Y)	6.05%	22.61%

Frequently asked

Which has the lower trailing P/E, CVS or VRTX?: CVS has the lower trailing P/E: CVS trades at 25.04 and VRTX at 30.00. P/E is one valuation measure and does not by itself establish which business is cheaper.
Which has grown faster, CVS or VRTX?: Over the past five years, VRTX grew revenue faster — CVS at a 8.32% CAGR versus VRTX at 13.57%.
Does CVS or VRTX pay a bigger dividend?: CVS pays a dividend (2.79% yield), while VRTX has no payments in the available dividend history.
Is CVS or VRTX more profitable?: VRTX runs the higher net margin — CVS at 1.18% versus VRTX at 34.89%.
How have CVS and VRTX total returns compared?: Over the past 10 years, CVS delivered 3.54% and VRTX delivered 18.72% annualized total return. Past performance doesn't predict future results.

Go deeper

Full CVS analysis Full VRTX analysis Interactive comparison tool

Dig into the metrics

CVS Health P/E ratio Vertex Pharmaceuticals P/E ratio CVS Health dividend yield CVS Health ROE Vertex Pharmaceuticals ROE CVS Health operating margin Vertex Pharmaceuticals operating margin CVS Health revenue growth Vertex Pharmaceuticals revenue growth CVS Health free cash flow Vertex Pharmaceuticals free cash flow

CVS Health & Vertex Pharmaceuticals appear in these rankings

Highest Dividend Yield Stocks Highest Operating Margin Stocks Highest FCF Yield Stocks Highest 10-Year Total Return Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified September 11, 2026.