Is MDT or VRTX cheaper?

On trailing earnings, MDT is cheaper: MDT trades at a 21.50 P/E and VRTX at 26.39.

Which has grown faster, MDT or VRTX?

Over the past five years, VRTX grew revenue faster — MDT at a 5.18% CAGR versus VRTX at 13.82%.

Does MDT or VRTX pay a bigger dividend?

MDT pays a dividend (3.54% yield) while VRTX does not currently pay one.

Is MDT or VRTX more profitable?

VRTX runs the higher net margin — MDT at 13.20% versus VRTX at 35.40%.

Which has been the better investment, MDT or VRTX?

Over the past 10-year, VRTX delivered the higher annualized total return — MDT at 1.97% versus VRTX at 17.13%. Past performance doesn't predict future results.

Medtronic plc (MDT) vs Vertex Pharmaceuticals Incorporated (VRTX)

VRTX leads on 10 of 16 compared metrics, though MDT is the cheaper stock.

A side-by-side comparison of Medtronic plc and Vertex Pharmaceuticals Incorporated across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of June 13, 2026. The ● marks the stronger figure on each row (cheaper multiple, higher margin/return).

Vertex Pharmaceuticals Incorporated

$112.92B

$444.93Healthcare

Total return — MDT vs VRTX

growth of $100 · last 30y

MDT +462.8%VRTX +2389.1%VRTX compounded faster

MDT VRTX

MDT vs VRTX: by the numbers

•VRTX is the larger company ($112.92B vs $102.97B market cap).
•MDT trades at the lower earnings multiple (21.50 vs 26.39 P/E).
•VRTX converts more revenue to profit (35.40% vs 13.20% net margin).
•VRTX grew revenue faster over the past five years (13.82% vs 5.18% CAGR).
•MDT pays a dividend (3.54% yield) while VRTX does not currently pay one.

Which is better, MDT or VRTX?

Metric tally: MDT 6 · VRTX 10

It depends on what you're optimizing for:

ValueMDT(lower P/E)

GrowthVRTX(faster 5Y revenue CAGR)

QualityVRTX(higher ROIC)

Valuation

Metric	MDT	VRTX
P/E ratio	21.50●	26.39
Forward P/E	12.56●	20.58
P/S ratio	2.84●	9.31
P/B ratio	2.11●	5.89
PEG ratio	6.73	3.23●
EV / EBITDA	13.03●	20.72
FCF yield	5.25%●	3.25%

Profitability

Metric	MDT	VRTX
Gross margin	65.02%	86.28%●
Operating margin	17.78%	38.97%●
Net margin	13.20%	35.40%●
ROE	9.80%	22.41%●
ROIC	0.00%	18.12%●

Dividends

Metric	MDT	VRTX
Dividend yield	3.54%	—
Payout ratio	75.73%	—

Growth (annualized)

Metric	MDT	VRTX
Revenue CAGR (5Y)	5.18%	13.82%●
EPS CAGR (5Y)	0.83%	8.17%●
FCF CAGR (5Y)	3.07%	4.01%●
Total return CAGR (5Y)	-5.47%	18.17%●

Frequently asked

Which is better, MDT or VRTX?: It depends on your goal. value: MDT (lower P/E); growth: VRTX (faster 5Y revenue CAGR); quality: VRTX (higher ROIC). Across all compared metrics, VRTX leads 10 to 6.
Is MDT or VRTX cheaper?: On trailing earnings, MDT is cheaper: MDT trades at a 21.50 P/E and VRTX at 26.39.
Which has grown faster, MDT or VRTX?: Over the past five years, VRTX grew revenue faster — MDT at a 5.18% CAGR versus VRTX at 13.82%.
Does MDT or VRTX pay a bigger dividend?: MDT pays a dividend (3.54% yield) while VRTX does not currently pay one.
Is MDT or VRTX more profitable?: VRTX runs the higher net margin — MDT at 13.20% versus VRTX at 35.40%.
Which has been the better investment, MDT or VRTX?: Over the past 10-year, VRTX delivered the higher annualized total return — MDT at 1.97% versus VRTX at 17.13%. Past performance doesn't predict future results.

Go deeper

Full MDT analysis Full VRTX analysis Interactive comparison tool

Dig into the metrics

Medtronic P/E ratio Vertex Pharmaceuticals P/E ratio Medtronic dividend yield Vertex Pharmaceuticals dividend yield Medtronic ROE Vertex Pharmaceuticals ROE Medtronic operating margin Vertex Pharmaceuticals operating margin Medtronic revenue growth Vertex Pharmaceuticals revenue growth Medtronic free cash flow Vertex Pharmaceuticals free cash flow

Medtronic & Vertex Pharmaceuticals appear in these rankings

Highest Dividend Yield Stocks Dividend Aristocrats Highest ROIC Stocks Highest Operating Margin Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified June 13, 2026.