Basis: Latest stored market observation. Source: stored company filings and market data; unavailable inputs remain N/A.
Is the P/E ratio high or low?
The P/E ratio of 28.31 is in line with its 5-year average of 27.53, around the middle of its 5-year range (18.95–34.14).
As of Sunday, July 26, 2026. 3.77% below its 12-month average of 29.42.
PE Ratio (28.31) = Close Price ($477.36) / Diluted TTM EPS ($16.86)
PE RATIO
28.31
PE RATIO AVG TTM
29.42
PE RATIO AVG 3Y
29.32
PE RATIO AVG 5Y
27.53
PE RATIO AVG 10Y
29.79
PE RATIO AVG 15Y
34.60
PE RATIO AVG 20Y
N/A
CURRENT VS TTM AVG
-3.77%
CURRENT VS 3Y AVG
-3.44%
CURRENT VS 5Y AVG
+2.83%
CURRENT VS 10Y AVG
-4.96%
CURRENT VS 15Y AVG
-18.19%
CURRENT VS 20Y AVG
N/A
SECTOR MEDIAN · HEALTHCARE
27.83
median of 65 covered companies
CURRENT VS SECTOR MEDIAN
+1.72%
vs the sector median at left
Vertex Pharmaceuticals Incorporated
Market Cap
$121.16B
PE Ratio
28.31
TTM Avg
29.42
3Y Avg
29.32
5Y Avg
27.53
Market Cap
$119.53B
PE Ratio
38.40
TTM Avg
62.50
3Y Avg
73.34
5Y Avg
70.76
Market Cap
$126.79B
PE Ratio
17.44
TTM Avg
17.44
3Y Avg
16.21
5Y Avg
19.26
| NAME | MARKET CAP | PE RATIO | TTM | 3Y | 5Y |
|---|---|---|---|---|---|
| Vertex Pharmaceuticals Incorporated (VRTX) | $121.16B | 28.31 | 29.42 | 29.32 | 27.53 |
| Intuitive Surgical, Inc. (ISRG)vs › | $119.53B | 38.40 | 62.50 | 73.34 | 70.76 |
| Stryker Corporation (SYK)vs › | $126.60B | 38.22 | 44.34 | 43.35 | 43.90 |
| Bristol-Myers Squibb Company (BMY)vs › | $126.79B | 17.44 | 17.44 | 16.21 | 19.26 |
| Danaher Corporation (DHR)vs › | $134.62B | 34.01 | 41.31 | 39.12 | 34.92 |
| Medtronic plc (MDT)vs › | $106.51B | 22.31 | 24.94 | 26.68 | 28.03 |
| CVS Health Corp. (CVS)vs › | $137.47B | 47.46 | 85.40 | 38.61 | 31.52 |
| GSK plc (GSK)vs › | $103.60B | 11.36 | 14.35 | 15.19 | 13.15 |
| Pfizer Inc. (PFE)vs › | $139.86B | 18.73 | 16.47 | 22.90 | 18.12 |
| McKesson Corporation (MCK)vs › | $98.45B | 21.86 | 25.54 | 24.72 | 26.27 |
At 28.3, P/E is in its normal range, sitting higher than 45% of its 14-year history.
14-year low
17.9
median
29.1
14-year high
3208.0
Trailing P/E
28.3
Forward P/E
24.8
Forward P/E is calculated using analyst consensus EPS estimates for the current or next fiscal year.
Calculation:
Current Price
$477.36
Forward EPS (Est.)
$19.23
Forward P/E
24.83
Source: FMP Analyst Consensus Estimates. Forward EPS represents the average analyst estimate for the nearest fiscal year.
PE Ratio = Share Price / Diluted EPS (TTM)
The price-to-earnings ratio measures how much investors pay for each dollar of trailing earnings. A lower PE can indicate a cheaper valuation; a higher PE implies higher growth expectations.
Expanded definitions: Investopedia, Wikipedia, Corporate Finance Institute
| DATE | PE RATIO |
|---|---|
| 2026-07-24 | 28.31 |
| 2026-07-23 | 28.06 |
| 2026-07-22 | 28.03 |
| 2026-07-21 | 28.59 |
| 2026-07-20 | 28.50 |
| 2026-07-17 | 28.80 |
| 2026-07-16 | 28.83 |
| 2026-07-15 | 28.30 |
| 2026-07-14 | 28.25 |
| 2026-07-13 | 28.48 |
| 2026-07-10 | 28.79 |
| 2026-07-09 | 29.45 |
| 2026-07-08 | 29.56 |
| 2026-07-07 | 30.98 |
| 2026-07-06 | 31.41 |
| 2026-07-02 | 31.32 |
| 2026-07-01 | 29.54 |
| 2026-06-30 | 29.46 |
| 2026-06-29 | 29.64 |
| 2026-06-26 | 29.14 |
| 2026-06-25 | 28.48 |
| 2026-06-24 | 28.19 |
| 2026-06-23 | 27.78 |
| 2026-06-22 | 27.69 |
| 2026-06-18 | 26.79 |
| 2026-06-17 | 27.22 |
| 2026-06-16 | 26.88 |
| 2026-06-15 | 26.72 |
| 2026-06-12 | 26.39 |
| 2026-06-11 | 26.40 |
| 2026-06-10 | 25.84 |
| 2026-06-09 | 26.44 |
| 2026-06-08 | 26.27 |
| 2026-06-05 | 26.50 |
| 2026-06-04 | 26.20 |
| 2026-06-03 | 25.41 |
| 2026-06-02 | 25.21 |
| 2026-06-01 | 26.00 |
| 2026-05-29 | 26.54 |
| 2026-05-28 | 26.57 |
| 2026-05-27 | 25.93 |
| 2026-05-26 | 25.86 |
| 2026-05-22 | 25.77 |
| 2026-05-21 | 25.71 |
| 2026-05-20 | 25.53 |
| 2026-05-19 | 25.76 |
| 2026-05-18 | 25.89 |
| 2026-05-15 | 25.92 |
| 2026-05-14 | 26.71 |
| 2026-05-13 | 26.87 |
| 2026-05-12 | 26.59 |
| 2026-05-11 | 25.81 |
| 2026-05-08 | 25.49 |
| 2026-05-07 | 25.21 |
| 2026-05-06 | 25.36 |
| 2026-05-05 | 25.17 |
| 2026-05-04 | 28.04 |
| 2026-05-01 | 27.65 |
| 2026-04-30 | 27.88 |
| 2026-04-29 | 27.61 |
| 2026-04-28 | 28.06 |
| 2026-04-27 | 27.79 |
| 2026-04-24 | 28.07 |
| 2026-04-23 | 28.38 |
| 2026-04-22 | 28.55 |
| 2026-04-21 | 28.48 |
| 2026-04-20 | 28.65 |
| 2026-04-17 | 28.78 |
| 2026-04-16 | 28.42 |
| 2026-04-15 | 28.81 |
| 2026-04-14 | 28.98 |
| 2026-04-13 | 28.71 |
| 2026-04-10 | 28.46 |
| 2026-04-09 | 29.14 |
| 2026-04-08 | 28.96 |
| 2026-04-07 | 28.17 |
| 2026-04-06 | 28.33 |
| 2026-04-02 | 28.62 |
| 2026-04-01 | 29.18 |
| 2026-03-31 | 29.13 |
| 2026-03-30 | 28.91 |
| 2026-03-27 | 28.25 |
| 2026-03-26 | 29.60 |
| 2026-03-25 | 29.68 |
| 2026-03-24 | 29.26 |
| 2026-03-23 | 29.44 |
| 2026-03-20 | 29.62 |
| 2026-03-19 | 29.88 |
| 2026-03-18 | 29.46 |
| 2026-03-17 | 30.17 |
| 2026-03-16 | 30.40 |
| 2026-03-13 | 30.62 |
| 2026-03-12 | 31.19 |
| 2026-03-11 | 32.12 |
| 2026-03-10 | 32.56 |
| 2026-03-09 | 30.06 |
| 2026-03-06 | 29.79 |
| 2026-03-05 | 30.06 |
| 2026-03-04 | 31.17 |
| 2026-03-03 | 30.94 |
| 2026-03-02 | 31.70 |
| 2026-02-27 | 32.41 |
| 2026-02-26 | 31.32 |
| 2026-02-25 | 31.51 |
| 2026-02-24 | 31.80 |
| 2026-02-23 | 31.38 |
| 2026-02-20 | 31.11 |
| 2026-02-19 | 30.61 |
| 2026-02-18 | 30.68 |
| 2026-02-17 | 31.14 |
| 2026-02-13 | 32.06 |
| 2026-02-12 | 32.79 |
| 2026-02-11 | 32.53 |
| 2026-02-10 | 32.69 |
| 2026-02-09 | 33.21 |
| 2026-02-06 | 33.70 |
| 2026-02-05 | 32.36 |
| 2026-02-04 | 33.18 |
| 2026-02-03 | 32.84 |
| 2026-02-02 | 33.29 |
| 2026-01-30 | 33.14 |
| 2026-01-29 | 33.55 |
| 2026-01-28 | 33.70 |
| 2026-01-27 | 33.44 |
| 2026-01-26 | 33.63 |
| 2026-01-23 | 33.03 |
| 2026-01-22 | 32.96 |
| 2026-01-21 | 32.52 |
| 2026-01-20 | 31.18 |
| 2026-01-16 | 31.13 |
| 2026-01-15 | 30.95 |
| 2026-01-14 | 31.70 |
| 2026-01-13 | 32.06 |
| 2026-01-12 | 32.48 |
| 2026-01-09 | 32.71 |
| 2026-01-08 | 33.12 |
| 2026-01-07 | 34.14 |
| 2026-01-06 | 33.03 |
| 2026-01-05 | 31.65 |
| 2026-01-02 | 31.89 |
| 2025-12-31 | 31.97 |
| 2025-12-30 | 32.00 |
| 2025-12-29 | 32.42 |
| 2025-12-26 | 32.64 |
| 2025-12-24 | 32.65 |
| 2025-12-23 | 32.38 |
| 2025-12-22 | 32.46 |
| 2025-12-19 | 32.17 |
| 2025-12-18 | 31.55 |
| 2025-12-17 | 31.70 |
| 2025-12-16 | 32.08 |
| 2025-12-15 | 32.14 |
| 2025-12-12 | 31.88 |
| 2025-12-11 | 31.45 |
| 2025-12-10 | 31.36 |
| 2025-12-09 | 30.82 |
| 2025-12-08 | 31.17 |
| 2025-12-05 | 32.12 |
| 2025-12-04 | 32.25 |
| 2025-12-03 | 32.66 |
| 2025-12-02 | 30.55 |
| 2025-12-01 | 30.01 |
| 2025-11-28 | 30.58 |
| 2025-11-26 | 30.48 |
| 2025-11-25 | 30.31 |
| 2025-11-24 | 29.90 |
| 2025-11-21 | 30.10 |
| 2025-11-20 | 29.78 |
| 2025-11-19 | 29.69 |
| 2025-11-18 | 30.71 |
| 2025-11-17 | 30.61 |
| 2025-11-14 | 30.83 |
| 2025-11-13 | 30.64 |
| 2025-11-12 | 30.62 |
| 2025-11-11 | 30.27 |
| 2025-11-10 | 29.70 |
| 2025-11-07 | 28.88 |
| 2025-11-06 | 29.35 |
| 2025-11-05 | 29.41 |
| 2025-11-04 | 29.74 |
| 2025-11-03 | 30.45 |
| 2025-10-31 | 30.42 |
| 2025-10-30 | 30.01 |
| 2025-10-29 | 29.82 |
| 2025-10-28 | 30.19 |
| 2025-10-27 | 30.03 |
| 2025-10-24 | 30.12 |
| 2025-10-23 | 30.21 |
| 2025-10-22 | 30.48 |
| 2025-10-21 | 30.47 |
| 2025-10-20 | 29.96 |
| 2025-10-17 | 29.79 |
| 2025-10-16 | 29.21 |
| 2025-10-15 | 29.16 |
| 2025-10-14 | 29.47 |
| 2025-10-13 | 29.12 |
| 2025-10-10 | 29.15 |
| 2025-10-09 | 29.65 |
| 2025-10-08 | 30.10 |
| 2025-10-07 | 29.33 |
| 2025-10-06 | 28.80 |
| 2025-10-03 | 28.83 |
| 2025-10-02 | 29.22 |
| 2025-10-01 | 28.89 |
| 2025-09-30 | 27.99 |
| 2025-09-29 | 28.26 |
| 2025-09-26 | 27.57 |
| 2025-09-25 | 27.30 |
| 2025-09-24 | 26.92 |
| 2025-09-23 | 27.14 |
| 2025-09-22 | 27.39 |
| 2025-09-19 | 27.39 |
| 2025-09-18 | 27.67 |
| 2025-09-17 | 27.67 |
| 2025-09-16 | 27.97 |
| 2025-09-15 | 28.11 |
| 2025-09-12 | 28.20 |
| 2025-09-11 | 28.40 |
| 2025-09-10 | 27.77 |
| 2025-09-09 | 28.34 |
| 2025-09-08 | 28.25 |
| 2025-09-05 | 28.31 |
| 2025-09-04 | 28.37 |
| 2025-09-03 | 28.35 |
| 2025-09-02 | 28.66 |
| 2025-08-29 | 27.95 |
| 2025-08-28 | 28.02 |
| 2025-08-27 | 27.81 |
| 2025-08-26 | 27.68 |
| 2025-08-25 | 27.80 |
| 2025-08-22 | 28.24 |
| 2025-08-21 | 28.41 |
| 2025-08-20 | 28.19 |
| 2025-08-19 | 27.93 |
| 2025-08-18 | 27.87 |
| 2025-08-15 | 28.08 |
| 2025-08-14 | 27.90 |
| 2025-08-13 | 28.30 |
| 2025-08-12 | 27.72 |
| 2025-08-11 | 26.77 |
| 2025-08-08 | 26.20 |
| 2025-08-07 | 26.85 |
| 2025-08-06 | 27.57 |
| 2025-08-05 | 26.80 |
| 2024-08-01 | 32.82 |
| 2024-07-31 | 32.17 |
| 2024-07-30 | 32.62 |
| 2024-07-29 | 32.33 |
| 2024-07-26 | 32.14 |
| 2024-07-25 | 31.94 |
| 2024-07-24 | 31.85 |
| 2024-07-23 | 31.82 |
| 2024-07-22 | 32.18 |
| 2024-07-19 | 31.90 |
| 2024-07-18 | 31.68 |
| 2024-07-17 | 31.69 |
| 2024-07-16 | 31.73 |
| 2024-07-15 | 31.85 |
| 2024-07-12 | 31.72 |
| 2024-07-11 | 31.94 |
Showing the most recent 260 of 2,327 data points. The chart above shows the full history.