Basis: Trailing twelve months (TTM). Source: stored company filings and market data; unavailable inputs remain N/A.
Is the operating margin high or low?
The operating margin of -873.87% is 20% above its 5-year average of -1085.65%, near the high end of its 5-year range (-12156.85%–0.00%).
31.85% below its 12-month average of -662.76%.
Reported quarterly operating margin; no daily interpolation. Q2 FY2026 (2026-06-30): -247.07%.
OPERATING MARGIN
-873.87%
OPERATING MARGIN AVG TTM
-662.76%
OPERATING MARGIN AVG 3Y
-1100.79%
OPERATING MARGIN AVG 5Y
-1085.65%
OPERATING MARGIN AVG 10Y
-727.02%
OPERATING MARGIN AVG 15Y
-532.60%
OPERATING MARGIN AVG 20Y
N/A
CURRENT VS TTM AVG
-31.85%
CURRENT VS 3Y AVG
+20.61%
CURRENT VS 5Y AVG
+19.51%
CURRENT VS 10Y AVG
-20.20%
CURRENT VS 15Y AVG
-64.08%
CURRENT VS 20Y AVG
N/A
SECTOR MEDIAN · HEALTHCARE
0.00%
median of 496 covered companies
CURRENT VS SECTOR MEDIAN
N/A
vs the sector median at left
Agios Pharmaceuticals, Inc.
Market Cap
$1.87B
Operating Margin
-873.87%
TTM Avg
-662.76%
3Y Avg
-1100.79%
5Y Avg
-1085.65%
Market Cap
$1.89B
Operating Margin
-1.12%
TTM Avg
-4.89%
3Y Avg
-11.52%
5Y Avg
-13.12%
Market Cap
$1.83B
Operating Margin
2.61%
TTM Avg
3.43%
3Y Avg
5.52%
5Y Avg
6.07%
Market Cap
$1.78B
Operating Margin
-737.04%
TTM Avg
-849.82%
3Y Avg
-849.82%
5Y Avg
-849.82%
Market Cap
$1.78B
Operating Margin
-651.67%
TTM Avg
-787.38%
3Y Avg
-968.58%
5Y Avg
-820.03%
Market Cap
$1.95B
Operating Margin
-4454.21%
TTM Avg
-3427.90%
3Y Avg
-2683.37%
5Y Avg
-2097.52%
Market Cap
$1.96B
Operating Margin
-18.48%
TTM Avg
-24.30%
3Y Avg
-28.12%
5Y Avg
-27.55%
Market Cap
$1.76B
Operating Margin
1.20%
TTM Avg
-1.69%
3Y Avg
-4.84%
5Y Avg
-5.86%
| NAME | MARKET CAP | OPERATING MARGIN | TTM | 3Y | 5Y |
|---|---|---|---|---|---|
| Agios Pharmaceuticals, Inc. (AGIO) | $1.87B | -873.87% | -662.76% | -1100.79% | -1085.65% |
| BioLife Solutions, Inc. (BLFS)vs › | $1.89B | -1.12% | -4.89% | -11.52% | -13.12% |
| Astrana Health, Inc. (ASTH)vs › | $1.83B | 2.61% | 3.43% | 5.52% | 6.07% |
| Generate Biomedicines, Inc. (GENB)vs › | $1.78B | -737.04% | -849.82% | -849.82% | -849.82% |
| Intellia Therapeutics, Inc. (NTLA)vs › | $1.78B | -651.67% | -787.38% | -968.58% | -820.03% |
| Absci Corporation (ABSI)vs › | $1.95B | -4454.21% | -3427.90% | -2683.37% | -2097.52% |
| Establishment Labs Holdings Inc. (ESTA)vs › | $1.96B | -18.48% | -24.30% | -28.12% | -27.55% |
| Alignment Healthcare, Inc. (ALHC)vs › | $1.76B | 1.20% | -1.69% | -4.84% | -5.86% |
| Azenta, Inc. (AZTA)vs › | $1.97B | -3.49% | -3.57% | -5.95% | -5.03% |
| AxoGen, Inc. (AXGN)vs › | $2.00B | -5.12% | -2.62% | -10.04% | -13.46% |
Gross Margin
78.7%
Operating Margin
-873.9%
Operating Margin = Operating Income / Revenue
Operating margin is the percentage of revenue remaining after operating expenses, reflecting operating efficiency.
Expanded definitions: Investopedia, Wikipedia, Corporate Finance Institute
| DATE | OPERATING MARGIN |
|---|---|
| 2026-06-30 | -247.07% |
| 2026-03-31 | -530.34% |
| 2025-12-31 | -608.89% |
| 2025-09-30 | -907.37% |
| 2025-06-30 | -1020.12% |
| 2025-03-31 | -1221.97% |
| 2024-12-31 | -1165.30% |
| 2024-09-30 | -1146.93% |
| 2024-06-30 | -1228.29% |
| 2024-03-31 | -1124.34% |
| 2023-12-31 | -1496.23% |
| 2023-09-30 | -1363.66% |
| 2023-06-30 | -1396.01% |
| 2023-03-31 | -1615.49% |
| 2022-12-31 | -2300.97% |
| 2022-09-30 | -2590.73% |
| 2022-06-30 | -1749.19% |
| 2022-03-31 | -12156.85% |
| 2021-12-31 | 0.00% |
| 2021-09-30 | 0.00% |
| 2021-06-30 | 0.00% |
| 2021-03-31 | 0.00% |
| 2020-12-31 | -209.86% |
| 2020-09-30 | -260.26% |
| 2020-06-30 | -241.51% |
| 2020-03-31 | -49.59% |
| 2019-12-31 | -298.90% |
| 2019-09-30 | -419.07% |
| 2019-06-30 | -434.24% |
| 2019-03-31 | -322.50% |
| 2018-12-31 | -321.05% |
| 2018-09-30 | -652.47% |
| 2018-06-30 | -180.50% |
| 2018-03-31 | -1072.95% |
| 2017-12-31 | -919.79% |
| 2017-09-30 | -695.69% |
| 2017-06-30 | -745.64% |
| 2017-03-31 | -638.06% |
| 2016-12-31 | -253.48% |
| 2016-09-30 | -706.87% |
| 2016-06-30 | -809.26% |
| 2016-03-31 | -75.43% |
| 2015-12-31 | -657.72% |
| 2015-09-30 | -738.59% |
| 2015-06-30 | -243.08% |
| 2015-03-31 | -15.19% |
| 2014-12-31 | -182.61% |
| 2014-09-30 | 9.46% |
| 2014-06-30 | -217.93% |
| 2014-03-31 | -146.05% |
| 2013-12-31 | -181.52% |
| 2013-09-30 | -176.60% |
| 2013-06-30 | -136.02% |
| 2013-03-31 | -112.41% |
| 2012-12-31 | -103.42% |
| 2012-09-30 | -81.53% |
| 2012-06-30 | -97.38% |
| 2012-03-31 | -83.98% |
