Which has grown faster, AGIO or NTLA?

Over the past five years, NTLA grew revenue faster — AGIO at a 4.54% CAGR versus NTLA at 7.31%.

How have AGIO and NTLA total returns compared?

Over the past 10 years, AGIO delivered -5.39% and NTLA delivered -3.03% annualized total return. Past performance doesn't predict future results.

Agios Pharmaceuticals, Inc. (AGIO) vs Intellia Therapeutics, Inc. (NTLA)

A side-by-side comparison of Agios Pharmaceuticals, Inc. and Intellia Therapeutics, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

AGIO

Agios Pharmaceuticals, Inc.

$1.86B

$31.11HealthcareDelayed quote: Oct 6, 2026, 10:40 AM EDT

NTLA

Intellia Therapeutics, Inc.

$1.71B

$12.21HealthcareDelayed quote: Oct 6, 2026, 10:40 AM EDT

Total return — AGIO vs NTLA

growth of $100 · dividends reinvested · last 10y

AGIO -40.8% (-5.1%/yr)NTLA -26.5% (-3.0%/yr)NTLA compounded faster over this window

AGIO NTLA

AGIO vs NTLA: by the numbers

•AGIO is the larger company ($1.86B vs $1.71B market cap).
•Both run net losses; AGIO's is the smaller (-418.24% vs -672.16% net margin).
•NTLA grew revenue faster over the past five years (7.31% vs 4.54% CAGR).

Metrics side by side

Valuation

Metric	AGIO	NTLA
P/S ratio	18.89	28.66
P/B ratio	1.81	2.34

Profitability

Metric	AGIO	NTLA
Gross margin	78.67%	76.47%
Operating margin	-873.87%	-651.67%
Net margin	-418.24%	-672.16%
ROE	-40.09%	-54.96%
ROIC	-44.21%	-54.45%

Growth (annualized)

Metric	AGIO	NTLA
Revenue CAGR (5Y)	4.54%	7.31%
Total return CAGR (5Y)	-6.59%	-37.13%

Frequently asked

Which has grown faster, AGIO or NTLA?: Over the past five years, NTLA grew revenue faster — AGIO at a 4.54% CAGR versus NTLA at 7.31%.
How have AGIO and NTLA total returns compared?: Over the past 10 years, AGIO delivered -5.39% and NTLA delivered -3.03% annualized total return. Past performance doesn't predict future results.

Go deeper

Full AGIO analysis Full NTLA analysis Interactive comparison tool

Dig into the metrics

Agios Pharmaceuticals ROE Intellia Therapeutics ROE Agios Pharmaceuticals operating margin Intellia Therapeutics operating margin Agios Pharmaceuticals revenue growth Intellia Therapeutics revenue growth Agios Pharmaceuticals free cash flow Intellia Therapeutics free cash flow

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.