Agios Pharmaceuticals, Inc. (AGIO) vs AxoGen, Inc. (AXGN)

A side-by-side comparison of Agios Pharmaceuticals, Inc. and AxoGen, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

Compare

Total return — AGIO vs AXGN

growth of $100 · dividends reinvested · last 10y
AGIO -41.9% (-5.3%/yr)AXGN +332.8% (+15.8%/yr)AXGN compounded faster over this window
Log scale — wide-divergence pair
101001kStart $10020182020202220242026$58$433
AGIO AXGN

AGIO vs AXGN: by the numbers

  • •AXGN is the larger company ($1.96B vs $1.90B market cap).
  • •Both run net losses; AXGN's is the smaller (-13.36% vs -418.24% net margin).
  • •AXGN grew revenue faster over the past five years (13.99% vs 4.54% CAGR).

Metrics side by side

Valuation

MetricAGIOAXGN
Forward P/EN/A82.53
P/S ratio19.287.82
P/B ratio1.857.66
FCF yieldN/A0.13%

Profitability

MetricAGIOAXGN
Gross margin78.67%74.56%
Operating margin-873.87%-5.12%
Net margin-418.24%-13.36%
ROE-40.09%-13.09%
ROIC-44.21%-4.68%

Growth (annualized)

MetricAGIOAXGN
Revenue CAGR (5Y)4.54%13.99%
Total return CAGR (5Y)-6.59%19.40%

Frequently asked

Which has grown faster, AGIO or AXGN?
Over the past five years, AXGN grew revenue faster — AGIO at a 4.54% CAGR versus AXGN at 13.99%.
How have AGIO and AXGN total returns compared?
Over the past 10 years, AGIO delivered -5.39% and AXGN delivered 15.98% annualized total return. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.