Which has grown faster, AGIO or BLFS?

Over the past five years, BLFS grew revenue faster — AGIO at a 4.54% CAGR versus BLFS at 6.78%.

Is AGIO or BLFS more profitable?

BLFS runs the higher net margin — AGIO at -418.24% versus BLFS at 49.06%.

How have AGIO and BLFS total returns compared?

Over the past 10 years, AGIO delivered -5.39% and BLFS delivered 36.27% annualized total return. Past performance doesn't predict future results.

Agios Pharmaceuticals, Inc. (AGIO) vs BioLife Solutions, Inc. (BLFS)

A side-by-side comparison of Agios Pharmaceuticals, Inc. and BioLife Solutions, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

AGIO

Agios Pharmaceuticals, Inc.

$1.87B

$31.25HealthcareDelayed quote: Oct 5, 2026, 4:00 PM EDT

BLFS

BioLife Solutions, Inc.

$1.89B

$38.61HealthcareDelayed quote: Oct 5, 2026, 4:00 PM EDT

Total return — AGIO vs BLFS

growth of $100 · dividends reinvested · last 10y

AGIO -41.9% (-5.3%/yr)BLFS +2119.0% (+36.3%/yr)BLFS compounded faster over this window

Log scale — wide-divergence pair

AGIO BLFS

AGIO vs BLFS: by the numbers

•BLFS is the larger company ($1.89B vs $1.87B market cap).
•BLFS is profitable (49.06% net margin) while AGIO runs a net loss (-418.24%).
•BLFS grew revenue faster over the past five years (6.78% vs 4.54% CAGR).

Metrics side by side

Valuation

Metric	AGIO	BLFS
P/E ratio	N/A	37.72
Forward P/E	N/A	64.35
P/S ratio	18.97	18.35
P/B ratio	1.82	4.49
EV / EBITDA	N/A	170.26

Profitability

Metric	AGIO	BLFS
Gross margin	78.67%	64.48%
Operating margin	-873.87%	-1.12%
Net margin	-418.24%	49.06%
ROE	-40.09%	12.01%
ROIC	-44.21%	1.72%

Growth (annualized)

Metric	AGIO	BLFS
Revenue CAGR (5Y)	4.54%	6.78%
Total return CAGR (5Y)	-6.59%	-0.77%

Frequently asked

Which has grown faster, AGIO or BLFS?: Over the past five years, BLFS grew revenue faster — AGIO at a 4.54% CAGR versus BLFS at 6.78%.
Is AGIO or BLFS more profitable?: BLFS runs the higher net margin — AGIO at -418.24% versus BLFS at 49.06%.
How have AGIO and BLFS total returns compared?: Over the past 10 years, AGIO delivered -5.39% and BLFS delivered 36.27% annualized total return. Past performance doesn't predict future results.

Go deeper

Full AGIO analysis Full BLFS analysis Interactive comparison tool

Dig into the metrics

BioLife Solutions P/E ratio Agios Pharmaceuticals ROE BioLife Solutions ROE Agios Pharmaceuticals operating margin BioLife Solutions operating margin Agios Pharmaceuticals revenue growth BioLife Solutions revenue growth Agios Pharmaceuticals free cash flow BioLife Solutions free cash flow

Agios Pharmaceuticals & BioLife Solutions appear in these rankings

Highest 10-Year Total Return Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.