Basis: Trailing twelve months (TTM net income over TTM revenue). Source: stored company filings and market data; unavailable inputs remain N/A.
Is the net profit margin high or low?
The net profit margin of -80.67% is 96% above its 5-year average of -1806.64%, near the high end of its 5-year range (-144478.00%–78.50%).
99.63% above its 12-month average of -21787.82%.
Reported quarterly profit margin; no daily interpolation. Q2 FY2026 (2026-06-30): -1839.90%.
NET PROFIT MARGIN
-80.67%
NET PROFIT MARGIN AVG TTM
-21787.82%
NET PROFIT MARGIN AVG 3Y
-1835.73%
NET PROFIT MARGIN AVG 5Y
-1806.64%
NET PROFIT MARGIN AVG 10Y
-9029.20%
NET PROFIT MARGIN AVG 15Y
-7074.38%
NET PROFIT MARGIN AVG 20Y
N/A
CURRENT VS TTM AVG
+99.63%
CURRENT VS 3Y AVG
+95.61%
CURRENT VS 5Y AVG
+95.53%
CURRENT VS 10Y AVG
+99.11%
CURRENT VS 15Y AVG
+98.86%
CURRENT VS 20Y AVG
N/A
SECTOR MEDIAN · HEALTHCARE
-0.35%
median of 862 covered companies
CURRENT VS SECTOR MEDIAN
-22948.57%
vs the sector median at left
Prothena Corporation plc
Market Cap
$419.87M
Net Profit Margin
-80.67%
TTM Avg
-21787.82%
3Y Avg
-1835.73%
5Y Avg
-1806.64%
Market Cap
$418.95M
Net Profit Margin
-157.32%
TTM Avg
-564.37%
3Y Avg
-610.78%
5Y Avg
-554.09%
Market Cap
$422.72M
Net Profit Margin
-12.90%
TTM Avg
-139.82%
3Y Avg
-135.58%
5Y Avg
-114.97%
Market Cap
$422.86M
Net Profit Margin
0.00%
TTM Avg
0.00%
3Y Avg
0.00%
5Y Avg
0.00%
Market Cap
$416.27M
Net Profit Margin
-225.34%
TTM Avg
-272.94%
3Y Avg
12.89%
5Y Avg
-949.96%
Market Cap
$424.10M
Net Profit Margin
-6.77%
TTM Avg
-13.38%
3Y Avg
-17.48%
5Y Avg
-11.79%
Market Cap
$426.51M
Net Profit Margin
-184.24%
TTM Avg
-97.14%
3Y Avg
-46011.59%
5Y Avg
-30736.66%
Market Cap
$411.21M
Net Profit Margin
0.00%
TTM Avg
0.00%
3Y Avg
0.00%
5Y Avg
0.00%
| NAME | MARKET CAP | NET PROFIT MARGIN | TTM | 3Y | 5Y |
|---|---|---|---|---|---|
| Prothena Corporation plc (PRTA) | $419.87M | -80.67% | -21787.82% | -1835.73% | -1806.64% |
| Editas Medicine, Inc. (EDIT)vs › | $418.95M | -157.32% | -564.37% | -610.78% | -554.09% |
| Tilray Brands, Inc. (TLRY)vs › | $422.72M | -12.90% | -139.82% | -135.58% | -114.97% |
| Tectonic Therapeutic, Inc. (TECX)vs › | $422.86M | 0.00% | 0.00% | 0.00% | 0.00% |
| Senseonics Holdings, Inc. (SENS)vs › | $416.27M | -225.34% | -272.94% | 12.89% | -949.96% |
| Rezolute, Inc. (RZLT)vs › | $415.98M | 0.00% | 0.00% | 0.00% | 0.00% |
| NeoGenomics, Inc. (NEO)vs › | $424.10M | -6.77% | -13.38% | -17.48% | -11.79% |
| ARS Pharmaceuticals, Inc. (SPRY)vs › | $426.51M | -184.24% | -97.14% | -46011.59% | -30736.66% |
| MapLight Therapeutics, Inc. (MPLT)vs › | $411.21M | 0.00% | 0.00% | 0.00% | 0.00% |
| Strata Critical Medical, Inc. (SRTA)vs › | $411.00M | 15.71% | 4.99% | -8.39% | -22.57% |
Operating Margin
-1905.8%
Net Profit Margin
-80.7%
Net Profit Margin = Net Income / Revenue
Net profit margin is the percentage of revenue that becomes net income after all expenses, taxes, and interest.
Expanded definitions: Investopedia, Wikipedia, Corporate Finance Institute
| DATE | NET PROFIT MARGIN |
|---|---|
| 2026-06-30 | -1839.90% |
| 2026-03-31 | 64.05% |
| 2025-12-31 | -102804.76% |
| 2025-09-30 | -1513.08% |
| 2025-06-30 | -2845.41% |
| 2025-03-31 | -2128.54% |
| 2024-12-31 | -2729.91% |
| 2024-09-30 | -6082.58% |
| 2024-06-30 | 50.67% |
| 2024-03-31 | -144478.00% |
| 2023-12-31 | -21353.16% |
| 2023-09-30 | 25.81% |
| 2023-06-30 | -1358.42% |
| 2023-03-31 | -2160.63% |
| 2022-12-31 | 12.72% |
| 2022-09-30 | -3016.74% |
| 2022-06-30 | -3143.60% |
| 2022-03-31 | -3147.44% |
| 2021-12-31 | -2830.97% |
| 2021-09-30 | 78.50% |
| 2021-06-30 | 46.02% |
| 2021-03-31 | -22959.38% |
| 2020-12-31 | -8532.22% |
| 2020-09-30 | -19475.80% |
| 2020-06-30 | -13477.95% |
| 2020-03-31 | -16715.60% |
| 2019-12-31 | -8419.53% |
| 2019-09-30 | -9486.83% |
| 2019-06-30 | -9467.07% |
| 2019-03-31 | -11217.74% |
| 2018-12-31 | -11577.84% |
| 2018-09-30 | -9630.98% |
| 2018-06-30 | -21463.08% |
| 2018-03-31 | -21472.69% |
| 2017-12-31 | -20855.02% |
| 2017-09-30 | -23924.20% |
| 2017-06-30 | -66.02% |
| 2017-03-31 | -13661.78% |
| 2016-12-31 | -28598.25% |
| 2016-09-30 | -15118.53% |
| 2016-06-30 | -12145.65% |
| 2016-03-31 | -10385.28% |
| 2015-12-31 | -7868.73% |
| 2015-09-30 | -5355.71% |
| 2015-06-30 | -6574.46% |
| 2015-03-31 | -2563.58% |
| 2014-12-31 | -651.27% |
| 2014-09-30 | -887.08% |
| 2014-06-30 | 8.53% |
| 2014-03-31 | 55.38% |
| 2013-12-31 | -6619.16% |
| 2013-09-30 | -5666.08% |
| 2013-06-30 | -6767.66% |
| 2013-03-31 | -5234.50% |
| 2012-12-31 | -2125.39% |
| 2012-09-30 | -918.22% |
| 2012-06-30 | -1321.22% |
| 2012-03-31 | -2675.99% |
