Basis: Trailing twelve months (TTM). Source: stored company filings and market data; unavailable inputs remain N/A.
Is the gross margin high or low?
The gross margin of 61.77% is 107% above its 5-year average of -830.66%, near the high end of its 5-year range (-19485.76%–100.00%).
105.96% above its 12-month average of -1037.15%.
Reported quarterly gross margin; no daily interpolation. Q2 FY2026 (2026-06-30): 100.00%.
GROSS MARGIN
61.77%
GROSS MARGIN AVG TTM
-1037.15%
GROSS MARGIN AVG 3Y
-142.00%
GROSS MARGIN AVG 5Y
-830.66%
GROSS MARGIN AVG 10Y
-5849.09%
GROSS MARGIN AVG 15Y
-4260.70%
GROSS MARGIN AVG 20Y
N/A
CURRENT VS TTM AVG
+105.96%
CURRENT VS 3Y AVG
+143.50%
CURRENT VS 5Y AVG
+107.44%
CURRENT VS 10Y AVG
+101.06%
CURRENT VS 15Y AVG
+101.45%
CURRENT VS 20Y AVG
N/A
SECTOR MEDIAN · HEALTHCARE
39.56%
median of 749 covered companies
CURRENT VS SECTOR MEDIAN
+56.14%
vs the sector median at left
Prothena Corporation plc
Market Cap
$417.78M
Gross Margin
61.77%
TTM Avg
-1037.15%
3Y Avg
-142.00%
5Y Avg
-830.66%
Market Cap
$420.85M
Gross Margin
44.71%
TTM Avg
23.54%
3Y Avg
19.38%
5Y Avg
-46.55%
Market Cap
$414.53M
Gross Margin
0.00%
TTM Avg
0.00%
3Y Avg
0.00%
5Y Avg
0.00%
Market Cap
$412.94M
Gross Margin
0.00%
TTM Avg
0.00%
3Y Avg
0.00%
5Y Avg
12.37%
Market Cap
$411.03M
Gross Margin
77.34%
TTM Avg
76.74%
3Y Avg
77.57%
5Y Avg
77.57%
Market Cap
$410.07M
Gross Margin
0.00%
TTM Avg
-125.52%
3Y Avg
-62.76%
5Y Avg
-41.84%
Market Cap
$408.49M
Gross Margin
68.83%
TTM Avg
69.91%
3Y Avg
69.67%
5Y Avg
69.68%
| NAME | MARKET CAP | GROSS MARGIN | TTM | 3Y | 5Y |
|---|---|---|---|---|---|
| Prothena Corporation plc (PRTA) | $417.78M | 61.77% | -1037.15% | -142.00% | -830.66% |
| Rezolute, Inc. (RZLT)vs › | $418.87M | 0.00% | 0.00% | 0.00% | 0.00% |
| Senseonics Holdings, Inc. (SENS)vs › | $420.85M | 44.71% | 23.54% | 19.38% | -46.55% |
| Eikon Therapeutics, Inc. Common Stock (EIKN)vs › | $414.53M | 0.00% | 0.00% | 0.00% | 0.00% |
| Atea Pharmaceuticals, Inc. (AVIR)vs › | $412.94M | 0.00% | 0.00% | 0.00% | 12.37% |
| Shoulder Innovations, Inc. (SI)vs › | $411.03M | 77.34% | 76.74% | 77.57% | 77.57% |
| Neurogene Inc. (NGNE)vs › | $410.07M | 0.00% | -125.52% | -62.76% | -41.84% |
| Myriad Genetics, Inc. (MYGN)vs › | $408.49M | 68.83% | 69.91% | 69.67% | 69.68% |
| Carlsmed, Inc. (CARL)vs › | $404.78M | 76.63% | 74.56% | 73.66% | 73.66% |
| NeoGenomics, Inc. (NEO)vs › | $431.16M | 42.92% | 41.39% | 40.24% | 40.24% |
Gross Margin
61.8%
(Revenue - COGS) / Revenue
Gross Margin = Gross Profit / Revenue
Gross margin is the percentage of revenue remaining after the cost of goods sold, reflecting core product profitability.
Expanded definitions: Investopedia, Wikipedia, Corporate Finance Institute
| DATE | GROSS MARGIN |
|---|---|
| 2026-06-30 | 100.00% |
| 2026-03-31 | 98.20% |
| 2025-12-31 | -4385.71% |
| 2025-09-30 | -1098.26% |
| 2025-06-30 | 100.00% |
| 2025-03-31 | 100.00% |
| 2024-12-31 | 100.00% |
| 2024-09-30 | 100.00% |
| 2024-06-30 | 100.00% |
| 2024-03-31 | 100.00% |
| 2023-12-31 | -19485.76% |
| 2023-09-30 | 31.76% |
| 2023-06-30 | -1293.66% |
| 2023-03-31 | -1963.44% |
| 2022-12-31 | 26.14% |
| 2022-09-30 | -2527.55% |
| 2022-06-30 | -2306.17% |
| 2022-03-31 | -2264.44% |
| 2021-12-31 | -1782.08% |
| 2021-09-30 | 87.07% |
| 2021-06-30 | 64.89% |
| 2021-03-31 | -13115.00% |
| 2020-12-31 | -5666.67% |
| 2020-09-30 | -13661.15% |
| 2020-06-30 | -8756.92% |
| 2020-03-31 | -10714.18% |
| 2019-12-31 | -5943.36% |
| 2019-09-30 | -5990.73% |
| 2019-06-30 | -5638.32% |
| 2019-03-31 | -7048.39% |
| 2018-12-31 | -8410.31% |
| 2018-09-30 | -7160.78% |
| 2018-06-30 | -11173.12% |
| 2018-03-31 | -15188.99% |
| 2017-12-31 | -14529.69% |
| 2017-09-30 | -18765.30% |
| 2017-06-30 | -26.93% |
| 2017-03-31 | -9822.01% |
| 2016-12-31 | -23200.58% |
| 2016-09-30 | -9283.92% |
| 2016-06-30 | -9617.42% |
| 2016-03-31 | -7633.21% |
| 2015-12-31 | -5727.36% |
| 2015-09-30 | -3905.83% |
| 2015-06-30 | -4501.08% |
| 2015-03-31 | -1682.97% |
| 2014-12-31 | -402.09% |
| 2014-09-30 | -599.06% |
| 2014-06-30 | 43.03% |
| 2014-03-31 | 71.02% |
| 2013-12-31 | -3253.29% |
| 2013-09-30 | -3612.28% |
| 2013-06-30 | -4778.44% |
| 2013-03-31 | -3383.63% |
| 2012-12-31 | -1610.09% |
| 2012-09-30 | -697.67% |
| 2012-06-30 | 100.00% |
| 2012-03-31 | 100.00% |