Atea Pharmaceuticals, Inc. (AVIR) vs Prothena Corporation plc (PRTA)
A side-by-side comparison of Atea Pharmaceuticals, Inc. and Prothena Corporation plc across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
AVIR
Atea Pharmaceuticals, Inc.
$5.08HealthcareDelayed quote: Oct 6, 2026, 1:00 PM EDT
PRTA
Prothena Corporation plc
$7.90HealthcareDelayed quote: Oct 6, 2026, 1:00 PM EDT
Total return — AVIR vs PRTA
growth of $100 · dividends reinvested · last 6yAVIR -83.1% (-25.6%/yr)PRTA -26.6% (-5.0%/yr)PRTA compounded faster over this window
AVIR PRTA
AVIR vs PRTA: by the numbers
- •PRTA is the larger company ($414M vs $407M market cap).
- •Both run net losses; AVIR's is the smaller (0.00% vs -80.67% net margin).
Metrics side by side
Valuation
| Metric | AVIR | PRTA |
|---|---|---|
| Forward P/E | N/A | 71.82 |
| P/S ratio | N/A | 7.58 |
| P/B ratio | 1.99 | 1.44 |
Profitability
| Metric | AVIR | PRTA |
|---|---|---|
| Gross margin | 0.00% | 61.77% |
| Operating margin | 0.00% | -1905.82% |
| Net margin | 0.00% | -80.67% |
| ROE | -80.96% | -15.33% |
| ROIC | -89.93% | -21.36% |
Growth (annualized)
| Metric | AVIR | PRTA |
|---|---|---|
| Revenue CAGR (5Y) | N/A | 62.57% |
| Total return CAGR (5Y) | -34.44% | -35.08% |
Frequently asked
- How have AVIR and PRTA total returns compared?
- Over the past 5 years, AVIR delivered -34.44% and PRTA delivered -35.08% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Atea Pharmaceuticals ROEProthena ROEAtea Pharmaceuticals operating marginProthena operating marginAtea Pharmaceuticals revenue growthProthena revenue growthAtea Pharmaceuticals free cash flowProthena free cash flow
Atea Pharmaceuticals & Prothena appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.