Prothena Corporation (PRTA) Metrics: History & Chart

Prothena Corporation plc(PRTA)

Biotechnology · Dublin, DU

$8.02-0.25 (-3.02%)

Delayed quote: Oct 6, 2026, 4:00 PM EDT

About Prothena Corporation plc

Prothena Corporation plc, a late-stage clinical biotechnology company, focuses on discovery and development of novel therapies to treat diseases caused by protein dysregulation. Its product pipeline includes Prasinezumab, an investigational humanized monoclonal antibody which is in Phase 3 clinical trial for the treatment of parkinson's disease and other synucleinopathies. The company also develops Coramitug, an investigational antibody, which is in Phase 3 clinical trial for the treatment of transthyretin amyloidosis; BMS-986446, an anti-tau antibody which is in Phase 2 clinical trial to treat Alzheimer's disease; PRX019, an investigational antibody which is in Phase 1 clinical trial for the treatment of neurodegenerative diseases; and PRX123, a Dual Aß-Tau Vaccine, which is in preclinical trial for treating Alzheimer's disease. In addition, it develops discovery- and late-preclinical-stage programs include TDP-43 CYTOPE for the treatment of amyotrophic lateral sclerosis; PRX012, a next-generation anti-Aß antibody which is in phase 1 clinical trial to treat Alzheimer's disease; and PRX012-TfR, a preclinical program for the treatment of Alzheimer's disease. It has a license, development, and commercialization agreement with F. Hoffmann-La Roche Ltd. and Hoffmann-La Roche Inc. to develop and commercialize antibodies that target a-synuclein, including prasinezumab; and master collaboration agreement with Bristol Myers Squibb to develop and commercialize antibodies targeting tau, TDP-43. Prothena Corporation plc was incorporated in 2012 and is based in Dublin, Ireland.

Dublin, DU

67 employees

www.prothena.com

Healthcare / Biotechnology

Sector: Healthcare
Industry: Biotechnology
CEO: Gene G. Kinney

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Third-Party DCF Estimate (FMP)	$3.89
Price Gap vs Third-Party Estimate	-52.03%

7D Total Return	-5.16%
30D Total Return	-15.78%
YTD Total Return	-13.40%
1Y Total Return	-16.63%
3Y Total Return	-82.42%
5Y Total Return	-88.46%
10Y Total Return	-86.86%
15Y Total Return	N/A
20Y Total Return	N/A

2026	-13.40%
2025	-31.05%
2024	-61.89%
2023	-39.68%
2022	+21.96%
2021	+311.32%
2020

CAGR TTM	-16.56%
CAGR 3Y	-43.97%
CAGR 5Y	-35.08%
CAGR 10Y	-18.37%
CAGR 15Y	N/A
CAGR 20Y	N/A

PE Ratio	27.06
PE Ratio Avg TTM	31.82
PE Ratio Avg 3Y	31.82
Current VS TTM Avg	-14.97%
Current VS 3Y Avg	-14.97%
Current VS 5Y Avg	-14.97%

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PRTA FCF Yield

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PRTA EBITDA Yield

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PRTA EV/EBIT Ratio Metrics

PRTA EV/EBITDA Ratio Metrics

PRTA EV/Assets Ratio Metrics

PRTA EV/Sales Ratio Metrics

PRTA Current Ratio Metrics

PRTA Quick Ratio Metrics

PRTA ROIC Metrics

PRTA Return on Assets Metrics

PRTA Return on Equity Metrics

PRTA Net Profit Margin Metrics

PRTA Gross Profit Margin Metrics

PRTA Tax Rate Metrics

PS Ratio	7.91
PS Ratio Avg TTM	32.56
PS Ratio Avg 3Y	19.45
Current VS TTM Avg	-75.71%
Current VS 3Y Avg	-59.32%
Current VS 5Y Avg	-65.42%

PB Ratio	1.50
PB Ratio Avg TTM	1.71
PB Ratio Avg 3Y	1.73
Current VS TTM Avg	-12.14%
Current VS 3Y Avg	-13.29%
Current VS 5Y Avg	-50.41%

PFCF Ratio	166.02
PFCF Ratio Avg TTM	18.99
PFCF Ratio Avg 3Y	18.99
Current VS TTM Avg	+774.43%
Current VS 3Y Avg	+774.43%
Current VS 5Y Avg	+774.43%

Debt/Equity Ratio	0.02
Debt/Equity Ratio Avg TTM	0.03
Debt/Equity Ratio Avg 3Y	0.02
Current VS TTM Avg	-23.47%
Current VS 3Y Avg	+5.82%
Current VS 5Y Avg	+1.61%

PEG Ratio	N/A
PEG Ratio Avg TTM	N/A
PEG Ratio Avg 3Y	N/A
Current VS TTM Avg	N/A
Current VS 3Y Avg	N/A
Current VS 5Y Avg	N/A

FCF Yield	0.60%
FCF Yield Avg TTM	4.42%
FCF Yield Avg 3Y	4.42%
Current VS TTM Avg	-86.43%
Current VS 3Y Avg	-86.43%
Current VS 5Y Avg	-86.43%

Earnings Yield	3.70%
Earnings Yield Avg TTM	3.29%
Earnings Yield Avg 3Y	3.29%
Current VS TTM Avg	+12.54%
Current VS 3Y Avg	+12.54%
Current VS 5Y Avg	+12.54%

EBITDA Yield	N/A
EBITDA Yield Avg TTM	N/A
EBITDA Yield Avg 3Y	N/A
Current VS TTM Avg	N/A
Current VS 3Y Avg	N/A
Current VS 5Y Avg	N/A

OCF Yield	N/A
OCF Yield Avg TTM	N/A
OCF Yield Avg 3Y	N/A
Current VS TTM Avg	N/A
Current VS 3Y Avg	N/A
Current VS 5Y Avg	N/A

Ev/Ebit Ratio	15.26
Ev/Ebit Ratio Avg TTM	15.52
Ev/Ebit Ratio Avg 3Y	15.52
Current VS TTM Avg	-1.66%
Current VS 3Y Avg	-1.66%
Current VS 5Y Avg	-1.66%

Ev/Ebitda Ratio	15.04
Ev/Ebitda Ratio Avg TTM	15.28
Ev/Ebitda Ratio Avg 3Y	15.28
Current VS TTM Avg	-1.54%
Current VS 3Y Avg	-1.54%
Current VS 5Y Avg	-1.54%

Ev/Assets Ratio	0.50
Ev/Assets Ratio Avg TTM	0.58
Ev/Assets Ratio Avg 3Y	0.68
Current VS TTM Avg	-13.33%
Current VS 3Y Avg	-25.97%
Current VS 5Y Avg	-69.58%

Ev/Sales Ratio	2.75
Ev/Sales Ratio Avg TTM	12.93
Ev/Sales Ratio Avg 3Y	7.89
Current VS TTM Avg	-78.74%
Current VS 3Y Avg	-65.16%
Current VS 5Y Avg	-78.44%

Current Ratio	25.05
Current Ratio Avg TTM	11.10
Current Ratio Avg 3Y	10.02
Current VS TTM Avg	+125.69%
Current VS 3Y Avg	+150.00%
Current VS 5Y Avg	+114.53%

Quick Ratio	25.05
Quick Ratio Avg TTM	11.10
Quick Ratio Avg 3Y	10.02
Current VS TTM Avg	+125.69%
Current VS 3Y Avg	+150.00%
Current VS 5Y Avg	+114.53%

ROIC	(21.36%)
ROIC Avg 3Y	(27.91%)
ROIC Avg 5Y	(24.64%)
Current VS 3Y Avg	+23.49%
Current VS 5Y Avg	+13.33%
Current VS 10Y Avg	+25.04%

ROA	(14.54%)
ROA Avg TTM	(9.05%)
ROA Avg 3Y	(9.40%)
Current VS TTM Avg	-60.58%
Current VS 3Y Avg	-54.64%
Current VS 5Y Avg	-211.91%

ROE	(15.33%)
ROE Avg TTM	(67.84%)
ROE Avg 3Y	(24.40%)
Current VS TTM Avg	+77.40%
Current VS 3Y Avg	+37.18%
Current VS 5Y Avg	+9.04%

Net Profit Margin	(80.67%)
Net Profit Margin Avg TTM	(21787.82%)
Net Profit Margin Avg 3Y	(1835.73%)
Current VS TTM Avg	+99.63%
Current VS 3Y Avg	+95.61%
Current VS 5Y Avg	+95.53%

Gross Profit Margin	61.77%
Gross Pft Margin Avg TTM	(1037.15%)
Gross Pft Margin Avg 3Y	(142.00%)
Current VS TTM Avg	+105.96%
Current VS 3Y Avg	+143.50%
Current VS 5Y Avg	+107.44%

Tax Rate	0.00%
Tax Rate Avg 3Y	3.08%
Tax Rate Avg 5Y	7.05%
Current VS 3Y Avg	-99.90%
Current VS 5Y Avg	-99.96%
Current VS 10Y Avg	-99.96%