Prothena Corporation plc (PRTA) vs Tectonic Therapeutic, Inc. (TECX)
A side-by-side comparison of Prothena Corporation plc and Tectonic Therapeutic, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
PRTA
Prothena Corporation plc
$8.02HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT
TECX
Tectonic Therapeutic, Inc.
$22.41HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT
Total return — PRTA vs TECX
growth of $100 · dividends reinvested · last 8yPRTA -43.2% (-6.8%/yr)TECX -93.8% (-29.4%/yr)PRTA compounded faster over this window
Log scale — wide-divergence pair
PRTA TECX
PRTA vs TECX: by the numbers
- •TECX is the larger company ($423M vs $420M market cap).
- •Both run net losses; TECX's is the smaller (0.00% vs -80.67% net margin).
Metrics side by side
Valuation
| Metric | PRTA | TECX |
|---|---|---|
| Forward P/E | 72.91 | N/A |
| P/S ratio | 7.70 | N/A |
| P/B ratio | 1.46 | 1.89 |
Profitability
| Metric | PRTA | TECX |
|---|---|---|
| Gross margin | 61.77% | 0.00% |
| Operating margin | -1905.82% | 0.00% |
| Net margin | -80.67% | 0.00% |
| ROE | -15.33% | -38.32% |
| ROIC | -21.36% | -41.88% |
Growth (annualized)
| Metric | PRTA | TECX |
|---|---|---|
| Revenue CAGR (5Y) | 62.57% | N/A |
| Total return CAGR (5Y) | -35.08% | -18.45% |
Frequently asked
- How have PRTA and TECX total returns compared?
- Over the past 5 years, PRTA delivered -35.08% and TECX delivered -18.45% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Prothena ROETectonic Therapeutic ROEProthena operating marginTectonic Therapeutic operating marginProthena revenue growthTectonic Therapeutic revenue growthProthena free cash flowTectonic Therapeutic free cash flow
Prothena & Tectonic Therapeutic appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.