Prothena Corporation plc (PRTA) vs Strata Critical Medical, Inc. (SRTA)

A side-by-side comparison of Prothena Corporation plc and Strata Critical Medical, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

Compare

Total return — PRTA vs SRTA

growth of $100 · dividends reinvested · last 7y
PRTA -11.6% (-1.7%/yr)SRTA -50.7% (-9.6%/yr)PRTA compounded faster over this window
0200400600800Start $100202120232025$88$49
PRTA SRTA

PRTA vs SRTA: by the numbers

  • •SRTA is the larger company ($412M vs $412M market cap).
  • •SRTA is profitable (15.71% net margin) while PRTA runs a net loss (-80.67%).
  • •PRTA grew revenue faster over the past five years (62.57% vs 46.05% CAGR).

Metrics side by side

Valuation

MetricPRTASRTA
P/E ratioN/A9.57
Forward P/E71.48N/A
P/S ratio7.551.61
P/B ratio1.431.48

Profitability

MetricPRTASRTA
Gross margin61.77%20.56%
Operating margin-1905.82%-7.97%
Net margin-80.67%15.71%
ROE-15.33%14.40%
ROIC-21.36%-7.11%

Growth (annualized)

MetricPRTASRTA
Revenue CAGR (5Y)62.57%46.05%
Total return CAGR (5Y)-35.08%-13.77%

Frequently asked

Which has grown faster, PRTA or SRTA?
Over the past five years, PRTA grew revenue faster — PRTA at a 62.57% CAGR versus SRTA at 46.05%.
Is PRTA or SRTA more profitable?
SRTA runs the higher net margin — PRTA at -80.67% versus SRTA at 15.71%.
How have PRTA and SRTA total returns compared?
Over the past 5 years, PRTA delivered -35.08% and SRTA delivered -13.77% annualized total return. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.