Basis: Current FMP quote-based enterprise value / four-quarter operating cash flow less absolute capital expenditures. Source: stored company filings and market data; unavailable inputs remain N/A.
Is the EV/FCF ratio high or low?
The EV/FCF ratio of 64.85x is 27% above its estimated 2-year average of 51.20x, around the middle of its estimated 2-year range (7.69x–144.70x).
As of 2026-10-06T19:53:38.190Z. 31.22% below its estimated 12-month average of 94.28x.
Calculation as of: 2026-10-06T19:53:38.190Z.
Quote observation: 2026-10-06T19:50:44.000Z. Amounts in USD. The price header may show a later quote.
FMP input reference: 03323db2775440637d437753bcbe4752de1aa38160fb89fba54e51888a6c5dc1
Historical values estimate market capitalization from statement-period weighted shares. Comparisons with the current quote-based value are approximate. Only filing versions delivered by FMP are available for the historical calculation. Historical series through 2026-10-05.
Historical values estimate market capitalization from statement-period weighted shares. Comparisons with the current quote-based value are approximate. Only filing versions delivered by FMP are available for the historical calculation.
EV/FCF RATIO
64.85x
EV/FCF RATIO AVG TTM
94.28x
EV/FCF RATIO AVG 3Y
51.20x
EV/FCF RATIO AVG 5Y
51.20x
EV/FCF RATIO AVG 10Y
N/A
EV/FCF RATIO AVG 15Y
N/A
EV/FCF RATIO AVG 20Y
N/A
CURRENT VS TTM AVG
-31.22%
CURRENT VS 3Y AVG
+26.66%
CURRENT VS 5Y AVG
+26.66%
CURRENT VS 10Y AVG
N/A
CURRENT VS 15Y AVG
N/A
CURRENT VS 20Y AVG
N/A
SECTOR MEDIAN · HEALTHCARE
24.80x
median of 205 covered companies
CURRENT VS SECTOR MEDIAN
+161.49%
vs the sector median at left
Protagonist Therapeutics, Inc.
Market Cap
$8.88B
EV/FCF Ratio
64.85x
TTM Avg
94.28x
3Y Avg
51.20x
5Y Avg
51.20x
Market Cap
$8.93B
EV/FCF Ratio
113.51x
TTM Avg
1045.31x
3Y Avg
1026.30x
5Y Avg
1026.30x
Market Cap
$8.66B
EV/FCF Ratio
N/A
TTM Avg
34.26x
3Y Avg
34.16x
5Y Avg
34.16x
Market Cap
$8.65B
EV/FCF Ratio
N/A
TTM Avg
127.35x
3Y Avg
127.35x
5Y Avg
75.61x
Market Cap
$9.20B
EV/FCF Ratio
116.45x
TTM Avg
164.71x
3Y Avg
91.71x
5Y Avg
80.37x
| NAME | MARKET CAP | EV/FCF RATIO | TTM | 3Y | 5Y |
|---|---|---|---|---|---|
| Protagonist Therapeutics, Inc. (PTGX) | $8.88B | 64.85x | 94.28x | 51.20x | 51.20x |
| Axsome Therapeutics, Inc. (AXSM)vs › | $8.93B | N/A | N/A | N/A | N/A |
| Bruker Corporation (BRKRP)vs › | $8.93B | 113.51x | 1045.31x | 1026.30x | 1026.30x |
| Kymera Therapeutics, Inc. (KYMR)vs › | $8.66B | N/A | 34.26x | 34.16x | 34.16x |
| Arrowhead Pharmaceuticals, Inc. (ARWR)vs › | $8.65B | N/A | 127.35x | 127.35x | 75.61x |
| Bruker Corporation (BRKR)vs › | $9.20B | 116.45x | 164.71x | 91.71x | 80.37x |
| Insulet Corp. (PODD)vs › | $9.31B | 32.61x | 40.51x | 73.82x | 73.82x |
| Oscar Health, Inc. (OSCR)vs › | $8.38B | 1.09x | 2.20x | 3.82x | 3.92x |
| Vaxcyte, Inc. (PCVX)vs › | $9.52B | N/A | N/A | N/A | N/A |
| Krystal Biotech, Inc. (KRYS)vs › | $9.69B | 35.97x | 39.30x | 42.86x | 42.86x |
EV/FCF
64.8x
P/FCF
68.0x
FCF Yield
1.47%
Formula: EV/FCF = Enterprise Value / Free Cash Flow
EV/FCF vs P/FCF:
EV/FCF = Enterprise Value / Free Cash Flow (TTM)
Enterprise value to free cash flow compares total company value to the cash the business generates after capital expenditures.
Expanded definitions: Investopedia, Wikipedia, Corporate Finance Institute
| DATE | EV/FCF RATIO |
|---|---|
| 2026-10-05 | 73.32x |
| 2026-10-02 | 73.01x |
| 2026-10-01 | 72.54x |
| 2026-09-30 | 73.47x |
| 2026-09-29 | 73.51x |
| 2026-09-28 | 74.31x |
| 2026-09-25 | 73.99x |
| 2026-09-24 | 71.54x |
| 2026-09-23 | 72.27x |
| 2026-09-22 | 75.74x |
| 2026-09-21 | 75.69x |
| 2026-09-18 | 74.61x |
| 2026-09-17 | 74.99x |
| 2026-09-16 | 74.53x |
| 2026-09-15 | 74.83x |
| 2026-09-14 | 77.21x |
| 2026-09-11 | 77.43x |
| 2026-09-10 | 75.79x |
| 2026-09-09 | 75.75x |
| 2026-09-08 | 76.21x |
| 2026-09-04 | 76.09x |
| 2026-09-03 | 77.77x |
| 2026-09-02 | 76.29x |
| 2026-09-01 | 76.51x |
| 2026-08-31 | 77.20x |
| 2026-08-28 | 75.34x |
| 2026-08-27 | 78.15x |
| 2026-08-26 | 79.24x |
| 2026-08-25 | 78.74x |
| 2026-08-24 | 80.99x |
| 2026-08-21 | 80.77x |
| 2026-08-20 | 78.79x |
| 2026-08-19 | 81.11x |
| 2026-08-18 | 82.41x |
| 2026-08-17 | 83.11x |
| 2026-08-14 | 81.19x |
| 2026-08-13 | 79.19x |
| 2026-08-12 | 79.51x |
| 2026-08-11 | 77.49x |
| 2026-08-10 | 78.42x |
| 2026-08-07 | 76.17x |
| 2026-08-06 | 76.34x |
| 2026-05-05 | 110.36x |
| 2026-05-04 | 110.71x |
| 2026-05-01 | 109.41x |
| 2026-04-30 | 110.09x |
| 2026-04-29 | 109.58x |
| 2026-04-28 | 112.63x |
| 2026-04-27 | 109.56x |
| 2026-04-24 | 111.25x |
| 2026-04-23 | 114.22x |
| 2026-04-22 | 117.55x |
| 2026-04-21 | 117.93x |
| 2026-04-20 | 117.45x |
| 2026-04-17 | 118.03x |
| 2026-04-16 | 115.48x |
| 2026-04-15 | 117.42x |
| 2026-04-14 | 116.60x |
| 2026-04-13 | 108.50x |
| 2026-04-10 | 109.92x |
| 2026-04-09 | 115.89x |
| 2026-04-08 | 113.62x |
| 2026-04-07 | 115.51x |
| 2026-04-06 | 114.53x |
| 2026-04-02 | 115.54x |
| 2026-04-01 | 115.41x |
| 2026-03-31 | 117.38x |
| 2026-03-30 | 111.11x |
| 2026-03-27 | 110.09x |
| 2026-03-26 | 113.71x |
| 2026-03-25 | 116.14x |
| 2026-03-24 | 111.70x |
| 2026-03-23 | 109.60x |
| 2026-03-20 | 109.97x |
| 2026-03-19 | 113.16x |
| 2026-03-18 | 107.96x |
| 2026-03-17 | 108.11x |
| 2026-03-16 | 107.57x |
| 2026-03-13 | 102.59x |
| 2026-03-12 | 106.06x |
| 2026-03-11 | 107.26x |
| 2026-03-10 | 107.91x |
| 2026-03-09 | 107.47x |
| 2026-03-06 | 102.29x |
| 2026-03-05 | 101.52x |
| 2026-03-04 | 105.39x |
| 2026-03-03 | 101.39x |
| 2026-03-02 | 104.72x |
| 2026-02-27 | 102.28x |
| 2026-02-26 | 98.09x |
| 2026-02-25 | 85.57x |
| 2026-02-24 | 85.86x |
| 2026-02-23 | 85.06x |
| 2026-02-20 | 81.22x |
| 2026-02-19 | 81.55x |
| 2026-02-18 | 81.45x |
| 2026-02-17 | 80.92x |
| 2026-02-13 | 79.95x |
| 2026-02-12 | 80.39x |
| 2026-02-11 | 81.95x |
| 2026-02-10 | 82.34x |
| 2026-02-09 | 81.78x |
| 2026-02-06 | 82.95x |
| 2026-02-05 | 79.13x |
| 2026-02-04 | 81.76x |
| 2026-02-03 | 84.05x |
| 2026-02-02 | 81.51x |
| 2026-01-30 | 80.26x |
| 2026-01-29 | 78.19x |
| 2026-01-28 | 80.22x |
| 2026-01-27 | 81.54x |
| 2026-01-26 | 80.76x |
| 2026-01-23 | 81.56x |
| 2026-01-22 | 83.25x |
| 2026-01-21 | 82.35x |
| 2026-01-20 | 81.88x |
| 2026-01-16 | 80.45x |
| 2026-01-15 | 83.21x |
| 2026-01-14 | 83.69x |
| 2026-01-13 | 79.82x |
| 2026-01-12 | 78.71x |
| 2026-01-09 | 78.68x |
| 2026-01-08 | 78.66x |
| 2026-01-07 | 80.80x |
| 2026-01-06 | 80.73x |
| 2026-01-05 | 82.64x |
| 2026-01-02 | 85.65x |
| 2025-12-31 | 85.81x |
| 2025-12-30 | 85.73x |
| 2025-12-29 | 86.40x |
| 2025-12-26 | 87.25x |
| 2025-12-24 | 87.31x |
| 2025-12-23 | 87.20x |
| 2025-12-22 | 85.88x |
| 2025-12-19 | 84.52x |
| 2025-12-18 | 84.26x |
| 2025-12-17 | 87.81x |
| 2025-12-16 | 90.01x |
| 2025-12-15 | 93.26x |
| 2025-12-12 | 93.82x |
| 2025-12-11 | 90.72x |
| 2025-12-10 | 89.85x |
| 2025-12-09 | 87.03x |
| 2025-12-08 | 88.72x |
| 2025-12-05 | 88.12x |
| 2025-12-04 | 85.80x |
| 2025-12-03 | 84.54x |
| 2025-12-02 | 83.11x |
| 2025-12-01 | 84.11x |
| 2025-11-28 | 88.47x |
| 2025-11-26 | 88.54x |
| 2025-11-25 | 88.33x |
| 2025-11-24 | 86.16x |
| 2025-11-21 | 83.86x |
| 2025-11-20 | 82.66x |
| 2025-11-19 | 83.59x |
| 2025-11-18 | 82.85x |
| 2025-11-17 | 83.23x |
| 2025-11-14 | 83.07x |
| 2025-11-13 | 81.70x |
| 2025-11-12 | 83.31x |
| 2025-11-11 | 84.02x |
| 2025-11-10 | 81.69x |
| 2025-11-07 | 78.00x |
| 2025-11-06 | 132.34x |
| 2025-11-05 | 129.09x |
| 2025-11-04 | 126.72x |
| 2025-11-03 | 125.78x |
| 2025-10-31 | 130.35x |
| 2025-10-30 | 129.03x |
| 2025-10-29 | 127.05x |
| 2025-10-28 | 130.16x |
| 2025-10-27 | 124.58x |
| 2025-10-24 | 123.92x |
| 2025-10-23 | 122.43x |
| 2025-10-22 | 121.59x |
| 2025-10-21 | 124.16x |
| 2025-10-20 | 127.10x |
| 2025-10-17 | 128.44x |
| 2025-10-16 | 125.41x |
| 2025-10-15 | 128.74x |
| 2025-10-14 | 127.48x |
| 2025-10-13 | 131.29x |
| 2025-10-10 | 144.70x |
| 2025-10-09 | 110.53x |
| 2025-10-08 | 107.55x |
| 2025-10-07 | 107.84x |
| 2025-10-06 | 105.56x |
| 2025-10-03 | 106.75x |
| 2025-10-02 | 107.00x |
| 2025-10-01 | 105.32x |
| 2025-09-30 | 109.48x |
| 2025-09-29 | 107.28x |
| 2025-09-26 | 111.18x |
| 2025-09-25 | 106.52x |
| 2025-09-24 | 108.66x |
| 2025-09-23 | 107.14x |
| 2025-09-22 | 106.20x |
| 2025-09-19 | 102.24x |
| 2025-09-18 | 102.14x |
| 2025-09-17 | 97.14x |
| 2025-09-16 | 96.06x |
| 2025-09-15 | 95.70x |
| 2025-09-12 | 96.53x |
| 2025-09-11 | 97.93x |
| 2025-09-10 | 94.61x |
| 2025-09-09 | 95.67x |
| 2025-09-08 | 91.95x |
| 2025-09-05 | 99.38x |
| 2025-09-04 | 97.79x |
| 2025-09-03 | 95.24x |
| 2025-09-02 | 96.51x |
| 2025-08-29 | 96.85x |
| 2025-08-28 | 95.29x |
| 2025-08-27 | 100.93x |
| 2025-08-26 | 93.32x |
| 2025-08-25 | 93.14x |
| 2025-08-22 | 94.16x |
| 2025-08-21 | 91.70x |
| 2025-08-20 | 92.02x |
| 2025-08-19 | 92.06x |
| 2025-08-18 | 91.99x |
| 2025-08-15 | 91.75x |
| 2025-08-14 | 89.90x |
| 2025-08-13 | 92.86x |
| 2025-08-12 | 89.11x |
| 2025-08-11 | 87.78x |
| 2025-08-08 | 83.19x |
| 2025-08-07 | 83.00x |
| 2025-08-06 | 9.73x |
| 2025-08-05 | 9.74x |
| 2025-08-04 | 9.73x |
| 2025-08-01 | 9.73x |
| 2025-07-31 | 9.73x |
| 2025-07-30 | 9.87x |
| 2025-07-29 | 9.95x |
| 2025-07-28 | 10.18x |
| 2025-07-25 | 9.97x |
| 2025-07-24 | 9.71x |
| 2025-07-23 | 9.79x |
| 2025-07-22 | 9.94x |
| 2025-07-21 | 9.99x |
| 2025-07-18 | 10.04x |
| 2025-07-17 | 10.22x |
| 2025-07-16 | 10.25x |
| 2025-07-15 | 10.01x |
| 2025-07-14 | 9.99x |
| 2025-07-11 | 9.57x |
| 2025-07-10 | 9.54x |
| 2025-07-09 | 9.44x |
| 2025-07-08 | 8.95x |
| 2025-07-07 | 8.98x |
| 2025-07-03 | 9.20x |
| 2025-07-02 | 9.14x |
| 2025-07-01 | 9.05x |
| 2025-06-30 | 10.00x |
| 2025-06-27 | 10.08x |
| 2025-06-26 | 9.99x |
| 2025-06-25 | 9.84x |
| 2025-06-24 | 9.70x |
Showing the most recent 260 of 605 data points. The chart above shows the full history.
