Which has the lower trailing P/E, OSCR or PTGX?

OSCR has the lower trailing P/E: OSCR trades at 23.10 and PTGX at 134.17. P/E is one valuation measure and does not by itself establish which business is cheaper.

Which has grown faster, OSCR or PTGX?

Over the past five years, OSCR grew revenue faster — OSCR at a 64.83% CAGR versus PTGX at 59.63%.

Is OSCR or PTGX more profitable?

PTGX runs the higher net margin — OSCR at 3.60% versus PTGX at 29.40%.

How have OSCR and PTGX total returns compared?

Over the past 5 years, OSCR delivered 14.97% and PTGX delivered 50.88% annualized total return. Past performance doesn't predict future results.

Oscar Health, Inc. (OSCR) vs Protagonist Therapeutics, Inc. (PTGX)

A side-by-side comparison of Oscar Health, Inc. and Protagonist Therapeutics, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

OSCR

Oscar Health, Inc.

$8.38B

$32.34HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT

PTGX

Protagonist Therapeutics, Inc.

$8.92B

$138.69HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT

Total return — OSCR vs PTGX

growth of $100 · dividends reinvested · last 6y

OSCR -6.8% (-1.2%/yr)PTGX +379.1% (+29.8%/yr)PTGX compounded faster over this window

Log scale — wide-divergence pair

OSCR PTGX

OSCR vs PTGX: by the numbers

•PTGX is the larger company ($8.92B vs $8.38B market cap).
•OSCR trades at the lower trailing earnings multiple (23.10 vs 134.17 P/E), one valuation lens rather than an overall verdict.
•PTGX converts more revenue to profit (29.40% vs 3.60% net margin).
•OSCR grew revenue faster over the past five years (64.83% vs 59.63% CAGR).

Metrics side by side

Valuation

Metric	OSCR	PTGX
P/E ratio	23.10	134.17
Forward P/E	16.94	N/A
P/S ratio	0.55	31.63
P/B ratio	4.09	10.60
EV / EBITDA	7.27	142.09
FCF yield	51.70%	1.46%

Profitability

Metric	OSCR	PTGX
Gross margin	14.38%	99.86%
Operating margin	4.07%	-343.63%
Net margin	3.60%	29.40%
ROE	26.84%	9.85%
ROIC	22.98%	6.74%

Growth (annualized)

Metric	OSCR	PTGX
Revenue CAGR (5Y)	64.83%	59.63%
FCF CAGR (5Y)	80.81%	N/A
Total return CAGR (5Y)	14.97%	50.88%

Frequently asked

Which has the lower trailing P/E, OSCR or PTGX?: OSCR has the lower trailing P/E: OSCR trades at 23.10 and PTGX at 134.17. P/E is one valuation measure and does not by itself establish which business is cheaper.
Which has grown faster, OSCR or PTGX?: Over the past five years, OSCR grew revenue faster — OSCR at a 64.83% CAGR versus PTGX at 59.63%.
Is OSCR or PTGX more profitable?: PTGX runs the higher net margin — OSCR at 3.60% versus PTGX at 29.40%.
How have OSCR and PTGX total returns compared?: Over the past 5 years, OSCR delivered 14.97% and PTGX delivered 50.88% annualized total return. Past performance doesn't predict future results.

Go deeper

Full OSCR analysis Full PTGX analysis Interactive comparison tool

Dig into the metrics

Oscar Health P/E ratio Protagonist Therapeutics P/E ratio Oscar Health ROE Protagonist Therapeutics ROE Oscar Health operating margin Protagonist Therapeutics operating margin Oscar Health revenue growth Protagonist Therapeutics revenue growth Oscar Health free cash flow Protagonist Therapeutics free cash flow

Oscar Health & Protagonist Therapeutics appear in these rankings

Fastest Revenue Growth Stocks Highest ROE Stocks Highest ROIC Stocks Highest FCF Yield Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.