Basis: FMP quote price / unrounded diluted EPS from four consecutive issuer fiscal quarters. Source: stored company filings and market data; unavailable inputs remain N/A.
Is the P/E ratio high or low?
The P/E ratio of 134.17 is 120% above its 2-year average of 61.10, near the high end of its 2-year range (8.35–153.79).
As of 2026-10-06T22:47:58.086Z. 3.55% below its 12-month average of 139.11.
Calculation as of: 2026-10-06T22:47:58.086Z.
Quote observation: 2026-10-06T20:00:00.000Z. Amounts in USD. The price header may show a later quote.
FMP input reference: 03323db2775440637d437753bcbe4752de1aa38160fb89fba54e51888a6c5dc1
PE Ratio (134.17) = Close Price ($138.69) / Diluted TTM EPS ($1.03)
PE RATIO
134.17
PE RATIO AVG TTM
139.11
PE RATIO AVG 3Y
N/A
PE RATIO AVG 5Y
N/A
PE RATIO AVG 10Y
N/A
PE RATIO AVG 15Y
N/A
PE RATIO AVG 20Y
N/A
CURRENT VS TTM AVG
-3.55%
CURRENT VS 3Y AVG
N/A
CURRENT VS 5Y AVG
N/A
CURRENT VS 10Y AVG
N/A
CURRENT VS 15Y AVG
N/A
CURRENT VS 20Y AVG
N/A
SECTOR MEDIAN · HEALTHCARE
25.62
median of 186 covered companies
CURRENT VS SECTOR MEDIAN
+423.69%
vs the sector median at left
Protagonist Therapeutics, Inc.
Market Cap
$8.92B
PE Ratio
134.17
TTM Avg
139.11
3Y Avg
N/A
5Y Avg
N/A
Market Cap
$8.67B
PE Ratio
N/A
TTM Avg
41.90
3Y Avg
41.90
5Y Avg
41.90
| NAME | MARKET CAP | PE RATIO | TTM | 3Y | 5Y |
|---|---|---|---|---|---|
| Protagonist Therapeutics, Inc. (PTGX) | $8.92B | 134.17 | 139.11 | N/A | N/A |
| Bruker Corporation (BRKRP)vs › | $8.93B | N/A | 552.62 | 552.62 | 552.62 |
| Axsome Therapeutics, Inc. (AXSM)vs › | $8.97B | N/A | N/A | N/A | N/A |
| Kymera Therapeutics, Inc. (KYMR)vs › | $8.72B | N/A | N/A | N/A | N/A |
| Arrowhead Pharmaceuticals, Inc. (ARWR)vs › | $8.67B | N/A | 41.90 | 41.90 | 41.90 |
| Bruker Corporation (BRKR)vs › | $9.21B | N/A | 54.08 | 39.03 | 41.91 |
| Insulet Corp. (PODD)vs › | $9.33B | 25.18 | 58.80 | 65.23 | 3594.22 |
| Oscar Health, Inc. (OSCR)vs › | $8.38B | 23.10 | 22.16 | 45.57 | 45.57 |
| Vaxcyte, Inc. (PCVX)vs › | $9.63B | N/A | N/A | N/A | N/A |
| Krystal Biotech, Inc. (KRYS)vs › | $9.63B | 40.95 | 40.13 | 207.84 | 207.84 |
At 134.2, P/E is above its 2-year median — higher than 81% of readings in its 2-year history.
2-year low
8.3
median
18.2
2-year high
153.8
Trailing P/E
134.2
Forward P/E
N/A
Forward P/E is calculated using analyst consensus EPS estimates for the current or next fiscal year.
Calculation:
Current Price
$138.69
Forward EPS (Est.)
$4.67
Forward P/E
N/A
Source: FMP Analyst Consensus Estimates. Forward EPS represents the average analyst estimate for the nearest fiscal year.
PE Ratio = Share Price / Diluted EPS (TTM)
The price-to-earnings ratio measures how much investors pay for each dollar of trailing earnings. A lower PE can indicate a cheaper valuation; a higher PE implies higher growth expectations.
Expanded definitions: Investopedia, Wikipedia, Corporate Finance Institute
| DATE | PE RATIO |
|---|---|
| 2026-10-05 | 136.05 |
| 2026-10-02 | 135.49 |
| 2026-10-01 | 134.65 |
| 2026-09-30 | 136.30 |
| 2026-09-29 | 136.37 |
| 2026-09-28 | 137.80 |
| 2026-09-25 | 137.24 |
| 2026-09-24 | 132.86 |
| 2026-09-23 | 134.18 |
| 2026-09-22 | 140.34 |
| 2026-09-21 | 140.25 |
| 2026-09-18 | 138.34 |
| 2026-09-17 | 139.02 |
| 2026-09-16 | 138.18 |
| 2026-09-15 | 138.72 |
| 2026-09-14 | 142.96 |
| 2026-09-11 | 143.35 |
| 2026-09-10 | 140.43 |
| 2026-09-09 | 140.36 |
| 2026-09-08 | 141.18 |
| 2026-09-04 | 140.97 |
| 2026-09-03 | 143.95 |
| 2026-09-02 | 141.32 |
| 2026-09-01 | 141.71 |
| 2026-08-31 | 142.93 |
| 2026-08-28 | 139.62 |
| 2026-08-27 | 144.63 |
| 2026-08-26 | 146.56 |
| 2026-08-25 | 145.68 |
| 2026-08-24 | 149.68 |
| 2026-08-21 | 149.29 |
| 2026-08-20 | 145.78 |
| 2026-08-19 | 149.89 |
| 2026-08-18 | 152.21 |
| 2026-08-17 | 153.45 |
| 2026-08-14 | 150.04 |
| 2026-08-13 | 146.48 |
| 2026-08-12 | 147.05 |
| 2026-08-11 | 143.46 |
| 2026-08-10 | 145.11 |
| 2026-08-07 | 141.11 |
| 2026-08-06 | 141.41 |
| 2026-02-25 | 140.48 |
| 2026-02-24 | 140.95 |
| 2026-02-23 | 139.66 |
| 2026-02-20 | 133.48 |
| 2026-02-19 | 134.02 |
| 2026-02-18 | 133.85 |
| 2026-02-17 | 133.00 |
| 2026-02-13 | 131.44 |
| 2026-02-12 | 132.15 |
| 2026-02-11 | 134.66 |
| 2026-02-10 | 135.29 |
| 2026-02-09 | 134.39 |
| 2026-02-06 | 136.27 |
| 2026-02-05 | 130.11 |
| 2026-02-04 | 134.35 |
| 2026-02-03 | 138.05 |
| 2026-02-02 | 133.95 |
| 2026-01-30 | 131.94 |
| 2026-01-29 | 128.60 |
| 2026-01-28 | 131.87 |
| 2026-01-27 | 134.00 |
| 2026-01-26 | 132.74 |
| 2026-01-23 | 134.03 |
| 2026-01-22 | 136.76 |
| 2026-01-21 | 135.31 |
| 2026-01-20 | 134.55 |
| 2026-01-16 | 132.24 |
| 2026-01-15 | 136.69 |
| 2026-01-14 | 137.47 |
| 2026-01-13 | 131.23 |
| 2026-01-12 | 129.44 |
| 2026-01-09 | 129.39 |
| 2026-01-08 | 129.35 |
| 2026-01-07 | 132.81 |
| 2026-01-06 | 132.69 |
| 2026-01-05 | 135.77 |
| 2026-01-02 | 140.61 |
| 2025-12-31 | 140.87 |
| 2025-12-30 | 140.74 |
| 2025-12-29 | 141.82 |
| 2025-12-26 | 143.19 |
| 2025-12-24 | 143.29 |
| 2025-12-23 | 143.11 |
| 2025-12-22 | 140.98 |
| 2025-12-19 | 138.79 |
| 2025-12-18 | 138.37 |
| 2025-12-17 | 144.10 |
| 2025-12-16 | 147.65 |
| 2025-12-15 | 152.89 |
| 2025-12-12 | 153.79 |
| 2025-12-11 | 148.79 |
| 2025-12-10 | 147.39 |
| 2025-12-09 | 142.84 |
| 2025-12-08 | 145.56 |
| 2025-12-05 | 144.60 |
| 2025-12-04 | 140.85 |
| 2025-12-03 | 138.82 |
| 2025-12-02 | 136.53 |
| 2025-12-01 | 138.13 |
| 2025-11-28 | 145.16 |
| 2025-11-26 | 145.27 |
| 2025-11-25 | 144.94 |
| 2025-11-24 | 141.44 |
| 2025-11-21 | 137.74 |
| 2025-11-20 | 135.81 |
| 2025-11-19 | 137.31 |
| 2025-11-18 | 136.11 |
| 2025-11-17 | 136.73 |
| 2025-11-14 | 136.47 |
| 2025-11-13 | 134.26 |
| 2025-11-12 | 136.85 |
| 2025-11-11 | 138.00 |
| 2025-11-10 | 134.24 |
| 2025-11-07 | 128.29 |
| 2025-11-06 | 113.97 |
| 2025-11-05 | 111.26 |
| 2025-11-04 | 109.29 |
| 2025-11-03 | 108.50 |
| 2025-10-31 | 112.31 |
| 2025-10-30 | 111.21 |
| 2025-10-29 | 109.56 |
| 2025-10-28 | 112.16 |
| 2025-10-27 | 107.50 |
| 2025-10-24 | 106.94 |
| 2025-10-23 | 105.70 |
| 2025-10-22 | 105.00 |
| 2025-10-21 | 107.14 |
| 2025-10-20 | 109.60 |
| 2025-10-17 | 110.71 |
| 2025-10-16 | 108.19 |
| 2025-10-15 | 110.97 |
| 2025-10-14 | 109.91 |
| 2025-10-13 | 113.10 |
| 2025-10-10 | 124.29 |
| 2025-10-09 | 95.77 |
| 2025-10-08 | 93.29 |
| 2025-10-07 | 93.53 |
| 2025-10-06 | 91.63 |
| 2025-10-03 | 92.61 |
| 2025-10-02 | 92.83 |
| 2025-10-01 | 91.43 |
| 2025-09-30 | 94.90 |
| 2025-09-29 | 93.06 |
| 2025-09-26 | 96.31 |
| 2025-09-25 | 92.43 |
| 2025-09-24 | 94.21 |
| 2025-09-23 | 92.94 |
| 2025-09-22 | 92.16 |
| 2025-09-19 | 88.86 |
| 2025-09-18 | 88.77 |
| 2025-09-17 | 84.60 |
| 2025-09-16 | 83.70 |
| 2025-09-15 | 83.40 |
| 2025-09-12 | 84.09 |
| 2025-09-11 | 85.26 |
| 2025-09-10 | 82.49 |
| 2025-09-09 | 83.37 |
| 2025-09-08 | 80.27 |
| 2025-09-05 | 86.47 |
| 2025-09-04 | 85.14 |
| 2025-09-03 | 83.01 |
| 2025-09-02 | 84.07 |
| 2025-08-29 | 84.36 |
| 2025-08-28 | 83.06 |
| 2025-08-27 | 87.76 |
| 2025-08-26 | 81.41 |
| 2025-08-25 | 81.26 |
| 2025-08-22 | 82.11 |
| 2025-08-21 | 80.06 |
| 2025-08-20 | 80.33 |
| 2025-08-19 | 80.36 |
| 2025-08-18 | 80.30 |
| 2025-08-15 | 80.10 |
| 2025-08-14 | 78.56 |
| 2025-08-13 | 81.03 |
| 2025-08-12 | 77.90 |
| 2025-08-11 | 76.79 |
| 2025-08-08 | 72.96 |
| 2025-08-07 | 72.80 |
| 2025-08-06 | 71.83 |
| 2025-08-05 | 71.87 |
| 2025-08-04 | 71.77 |
| 2025-08-01 | 71.77 |
| 2025-07-31 | 71.81 |
| 2025-07-30 | 72.83 |
| 2025-07-29 | 73.35 |
| 2025-07-28 | 75.01 |
| 2025-07-25 | 73.53 |
| 2025-07-24 | 71.65 |
| 2025-07-23 | 72.25 |
| 2025-07-22 | 73.32 |
| 2025-07-21 | 73.63 |
| 2025-07-18 | 73.97 |
| 2025-07-17 | 75.25 |
| 2025-07-16 | 75.52 |
| 2025-07-15 | 73.76 |
| 2025-07-14 | 73.64 |
| 2025-07-11 | 70.67 |
| 2025-07-10 | 70.44 |
| 2025-07-09 | 69.72 |
| 2025-07-08 | 66.27 |
| 2025-07-07 | 66.49 |
| 2025-07-03 | 68.07 |
| 2025-07-02 | 67.59 |
| 2025-07-01 | 66.95 |
| 2025-06-30 | 73.69 |
| 2025-06-27 | 74.25 |
| 2025-06-26 | 73.63 |
| 2025-06-25 | 72.59 |
| 2025-06-24 | 71.57 |
| 2025-06-23 | 71.15 |
| 2025-06-20 | 71.12 |
| 2025-06-18 | 71.89 |
| 2025-06-17 | 73.61 |
| 2025-06-16 | 72.88 |
| 2025-06-13 | 75.16 |
| 2025-06-12 | 75.09 |
| 2025-06-11 | 73.79 |
| 2025-06-10 | 75.16 |
| 2025-06-09 | 74.24 |
| 2025-06-06 | 72.51 |
| 2025-06-05 | 71.76 |
| 2025-06-04 | 68.71 |
| 2025-06-03 | 68.08 |
| 2025-06-02 | 66.87 |
| 2025-05-30 | 63.29 |
| 2025-05-29 | 63.44 |
| 2025-05-28 | 61.00 |
| 2025-05-27 | 61.91 |
| 2025-05-23 | 60.88 |
| 2025-05-22 | 61.21 |
| 2025-05-21 | 61.09 |
| 2025-05-20 | 62.15 |
| 2025-05-19 | 60.76 |
| 2025-05-16 | 59.32 |
| 2025-05-15 | 59.21 |
| 2025-05-14 | 58.36 |
| 2025-05-13 | 59.03 |
| 2025-05-12 | 60.36 |
| 2025-05-09 | 57.29 |
| 2025-05-08 | 58.56 |
| 2025-05-07 | 57.45 |
| 2025-05-06 | 10.00 |
| 2025-05-05 | 10.54 |
| 2025-05-02 | 10.84 |
| 2025-05-01 | 10.71 |
| 2025-04-30 | 10.91 |
| 2025-04-29 | 10.86 |
| 2025-04-28 | 10.57 |
| 2025-04-25 | 10.59 |
| 2025-04-24 | 10.68 |
| 2025-04-23 | 10.99 |
| 2025-04-22 | 10.92 |
| 2025-04-21 | 10.90 |
| 2025-04-17 | 11.02 |
| 2025-04-16 | 10.90 |
| 2025-04-15 | 11.18 |
| 2025-04-14 | 10.72 |
Showing the most recent 260 of 493 data points. The chart above shows the full history.