Bruker Corporation (BRKR) vs Protagonist Therapeutics, Inc. (PTGX)

A side-by-side comparison of Bruker Corporation and Protagonist Therapeutics, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

Compare

Total return — BRKR vs PTGX

growth of $100 · dividends reinvested · last 10y
BRKR +196.6% (+11.5%/yr)PTGX +563.0% (+20.8%/yr)PTGX compounded faster over this window
0200400600Start $10020182020202220242026$297$663
BRKR PTGX

BRKR vs PTGX: by the numbers

  • •BRKR is the larger company ($9.24B vs $8.88B market cap).
  • •PTGX is profitable (29.40% net margin) while BRKR runs a net loss (-2.03%).
  • •PTGX grew revenue faster over the past five years (59.63% vs 9.10% CAGR).
  • •BRKR pays a dividend (0.23% yield), while PTGX has no payments in the available dividend history.

Metrics side by side

Valuation

MetricBRKRPTGX
P/E ratioN/A133.64
Forward P/E28.59N/A
P/S ratio2.6431.50
P/B ratio3.8510.56
EV / EBITDA30.75141.49
FCF yield1.02%1.47%

Profitability

MetricBRKRPTGX
Gross margin46.69%99.86%
Operating margin3.61%-343.63%
Net margin-2.03%29.40%
ROE-2.97%9.85%
ROIC2.56%6.74%

Dividends

MetricBRKRPTGX
Dividend yield0.23%N/A

Growth (annualized)

MetricBRKRPTGX
Revenue CAGR (5Y)9.10%59.63%
FCF CAGR (5Y)-21.33%N/A
Total return CAGR (5Y)-3.42%50.88%

Frequently asked

Which has grown faster, BRKR or PTGX?
Over the past five years, PTGX grew revenue faster — BRKR at a 9.10% CAGR versus PTGX at 59.63%.
Does BRKR or PTGX pay a bigger dividend?
BRKR pays a dividend (0.23% yield), while PTGX has no payments in the available dividend history.
Is BRKR or PTGX more profitable?
PTGX runs the higher net margin — BRKR at -2.03% versus PTGX at 29.40%.
How have BRKR and PTGX total returns compared?
Over the past 10 years, BRKR delivered 11.49% and PTGX delivered 20.54% annualized total return. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.