Bruker Corporation (BRKR) vs Protagonist Therapeutics, Inc. (PTGX)
A side-by-side comparison of Bruker Corporation and Protagonist Therapeutics, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
BRKR
Bruker Corporation
$60.67HealthcareDelayed quote: Oct 6, 2026, 3:15 PM EDT
PTGX
Protagonist Therapeutics, Inc.
$138.14HealthcareDelayed quote: Oct 6, 2026, 3:10 PM EDT
Total return — BRKR vs PTGX
growth of $100 · dividends reinvested · last 10yBRKR +196.6% (+11.5%/yr)PTGX +563.0% (+20.8%/yr)PTGX compounded faster over this window
BRKR PTGX
BRKR vs PTGX: by the numbers
- •BRKR is the larger company ($9.24B vs $8.88B market cap).
- •PTGX is profitable (29.40% net margin) while BRKR runs a net loss (-2.03%).
- •PTGX grew revenue faster over the past five years (59.63% vs 9.10% CAGR).
- •BRKR pays a dividend (0.23% yield), while PTGX has no payments in the available dividend history.
Metrics side by side
Valuation
| Metric | BRKR | PTGX |
|---|---|---|
| P/E ratio | N/A | 133.64 |
| Forward P/E | 28.59 | N/A |
| P/S ratio | 2.64 | 31.50 |
| P/B ratio | 3.85 | 10.56 |
| EV / EBITDA | 30.75 | 141.49 |
| FCF yield | 1.02% | 1.47% |
Profitability
| Metric | BRKR | PTGX |
|---|---|---|
| Gross margin | 46.69% | 99.86% |
| Operating margin | 3.61% | -343.63% |
| Net margin | -2.03% | 29.40% |
| ROE | -2.97% | 9.85% |
| ROIC | 2.56% | 6.74% |
Dividends
| Metric | BRKR | PTGX |
|---|---|---|
| Dividend yield | 0.23% | N/A |
Growth (annualized)
| Metric | BRKR | PTGX |
|---|---|---|
| Revenue CAGR (5Y) | 9.10% | 59.63% |
| FCF CAGR (5Y) | -21.33% | N/A |
| Total return CAGR (5Y) | -3.42% | 50.88% |
Frequently asked
- Which has grown faster, BRKR or PTGX?
- Over the past five years, PTGX grew revenue faster — BRKR at a 9.10% CAGR versus PTGX at 59.63%.
- Does BRKR or PTGX pay a bigger dividend?
- BRKR pays a dividend (0.23% yield), while PTGX has no payments in the available dividend history.
- Is BRKR or PTGX more profitable?
- PTGX runs the higher net margin — BRKR at -2.03% versus PTGX at 29.40%.
- How have BRKR and PTGX total returns compared?
- Over the past 10 years, BRKR delivered 11.49% and PTGX delivered 20.54% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Protagonist Therapeutics P/E ratioBruker dividend yieldBruker ROEProtagonist Therapeutics ROEBruker operating marginProtagonist Therapeutics operating marginBruker revenue growthProtagonist Therapeutics revenue growthBruker free cash flowProtagonist Therapeutics free cash flow
Bruker & Protagonist Therapeutics appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.