Basis: Current FMP quote-based enterprise value / four-quarter operating income. Source: stored company filings and market data; unavailable inputs remain N/A.
Is the EV/EBIT ratio high or low?
The EV/EBIT ratio of 145.40x is 45% above its estimated 2-year average of 100.55x, around the middle of its estimated 2-year range (8.87x–314.48x).
As of 2026-10-06T18:52:50.321Z. 37.61% below its estimated 12-month average of 233.04x.
Calculation as of: 2026-10-06T18:52:50.321Z.
Quote observation: 2026-10-06T18:50:02.000Z. Amounts in USD. The price header may show a later quote.
FMP input reference: 03323db2775440637d437753bcbe4752de1aa38160fb89fba54e51888a6c5dc1
Historical values estimate market capitalization from statement-period weighted shares. Comparisons with the current quote-based value are approximate. Only filing versions delivered by FMP are available for the historical calculation. Historical series through 2026-10-05.
Historical values estimate market capitalization from statement-period weighted shares. Comparisons with the current quote-based value are approximate. Only filing versions delivered by FMP are available for the historical calculation.
EV/EBIT RATIO
145.40x
EV/EBIT RATIO AVG TTM
233.04x
EV/EBIT RATIO AVG 3Y
N/A
EV/EBIT RATIO AVG 5Y
N/A
EV/EBIT RATIO AVG 10Y
N/A
EV/EBIT RATIO AVG 15Y
N/A
EV/EBIT RATIO AVG 20Y
N/A
CURRENT VS TTM AVG
-37.61%
CURRENT VS 3Y AVG
N/A
CURRENT VS 5Y AVG
N/A
CURRENT VS 10Y AVG
N/A
CURRENT VS 15Y AVG
N/A
CURRENT VS 20Y AVG
N/A
SECTOR MEDIAN · HEALTHCARE
22.76x
median of 197 covered companies
CURRENT VS SECTOR MEDIAN
+538.84%
vs the sector median at left
Protagonist Therapeutics, Inc.
Market Cap
$8.89B
EV/EBIT Ratio
145.40x
TTM Avg
233.04x
3Y Avg
N/A
5Y Avg
N/A
Market Cap
$8.79B
EV/EBIT Ratio
N/A
TTM Avg
57.60x
3Y Avg
57.60x
5Y Avg
57.60x
Market Cap
$8.91B
EV/EBIT Ratio
84.15x
TTM Avg
350.77x
3Y Avg
341.43x
5Y Avg
341.43x
Market Cap
$9.21B
EV/EBIT Ratio
86.51x
TTM Avg
55.05x
3Y Avg
39.77x
5Y Avg
33.84x
Market Cap
$8.41B
EV/EBIT Ratio
7.63x
TTM Avg
269.89x
3Y Avg
133.90x
5Y Avg
133.90x
| NAME | MARKET CAP | EV/EBIT RATIO | TTM | 3Y | 5Y |
|---|---|---|---|---|---|
| Protagonist Therapeutics, Inc. (PTGX) | $8.89B | 145.40x | 233.04x | N/A | N/A |
| Arrowhead Pharmaceuticals, Inc. (ARWR)vs › | $8.79B | N/A | 57.60x | 57.60x | 57.60x |
| Bruker Corporation (BRKRP)vs › | $8.91B | 84.15x | 350.77x | 341.43x | 341.43x |
| Axsome Therapeutics, Inc. (AXSM)vs › | $9.01B | N/A | N/A | N/A | N/A |
| Kymera Therapeutics, Inc. (KYMR)vs › | $8.69B | N/A | N/A | N/A | N/A |
| Bruker Corporation (BRKR)vs › | $9.21B | 86.51x | 55.05x | 39.77x | 33.84x |
| Oscar Health, Inc. (OSCR)vs › | $8.41B | 7.63x | 269.89x | 133.90x | 133.90x |
| Insulet Corp. (PODD)vs › | $9.37B | 18.96x | 34.29x | 59.67x | 167.52x |
| Vaxcyte, Inc. (PCVX)vs › | $9.42B | N/A | N/A | N/A | N/A |
| Krystal Biotech, Inc. (KRYS)vs › | $9.62B | 46.50x | 47.39x | 65.45x | 65.45x |
EV/EBIT = Enterprise Value / EBIT (TTM)
Enterprise value to EBIT compares total company value to operating earnings, accounting for depreciation unlike EV/EBITDA.
Expanded definitions: Investopedia, Wikipedia, Corporate Finance Institute
| DATE | EV/EBIT RATIO |
|---|---|
| 2026-10-05 | 164.12x |
| 2026-10-02 | 163.42x |
| 2026-10-01 | 162.36x |
| 2026-09-30 | 164.43x |
| 2026-09-29 | 164.53x |
| 2026-09-28 | 166.32x |
| 2026-09-25 | 165.61x |
| 2026-09-24 | 160.11x |
| 2026-09-23 | 161.77x |
| 2026-09-22 | 169.52x |
| 2026-09-21 | 169.41x |
| 2026-09-18 | 167.00x |
| 2026-09-17 | 167.85x |
| 2026-09-16 | 166.81x |
| 2026-09-15 | 167.49x |
| 2026-09-14 | 172.82x |
| 2026-09-11 | 173.30x |
| 2026-09-10 | 169.63x |
| 2026-09-09 | 169.54x |
| 2026-09-08 | 170.58x |
| 2026-09-04 | 170.31x |
| 2026-09-03 | 174.06x |
| 2026-09-02 | 170.75x |
| 2026-09-01 | 171.25x |
| 2026-08-31 | 172.78x |
| 2026-08-28 | 168.62x |
| 2026-08-27 | 174.91x |
| 2026-08-26 | 177.35x |
| 2026-08-25 | 176.24x |
| 2026-08-24 | 181.26x |
| 2026-08-21 | 180.78x |
| 2026-08-20 | 176.36x |
| 2026-08-19 | 181.53x |
| 2026-08-18 | 184.45x |
| 2026-08-17 | 186.01x |
| 2026-08-14 | 181.73x |
| 2026-08-13 | 177.25x |
| 2026-08-12 | 177.97x |
| 2026-08-11 | 173.44x |
| 2026-08-10 | 175.52x |
| 2026-08-07 | 170.49x |
| 2026-08-06 | 170.87x |
| 2026-02-25 | 286.81x |
| 2026-02-24 | 287.78x |
| 2026-02-23 | 285.09x |
| 2026-02-20 | 272.25x |
| 2026-02-19 | 273.35x |
| 2026-02-18 | 273.02x |
| 2026-02-17 | 271.24x |
| 2026-02-13 | 267.98x |
| 2026-02-12 | 269.46x |
| 2026-02-11 | 274.69x |
| 2026-02-10 | 276.00x |
| 2026-02-09 | 274.12x |
| 2026-02-06 | 278.05x |
| 2026-02-05 | 265.23x |
| 2026-02-04 | 274.06x |
| 2026-02-03 | 281.74x |
| 2026-02-02 | 273.22x |
| 2026-01-30 | 269.02x |
| 2026-01-29 | 262.08x |
| 2026-01-28 | 268.89x |
| 2026-01-27 | 273.32x |
| 2026-01-26 | 270.70x |
| 2026-01-23 | 273.39x |
| 2026-01-22 | 279.06x |
| 2026-01-21 | 276.04x |
| 2026-01-20 | 274.46x |
| 2026-01-16 | 269.66x |
| 2026-01-15 | 278.92x |
| 2026-01-14 | 280.53x |
| 2026-01-13 | 267.55x |
| 2026-01-12 | 263.82x |
| 2026-01-09 | 263.72x |
| 2026-01-08 | 263.66x |
| 2026-01-07 | 270.84x |
| 2026-01-06 | 270.60x |
| 2026-01-05 | 277.01x |
| 2026-01-02 | 287.07x |
| 2025-12-31 | 287.61x |
| 2025-12-30 | 287.34x |
| 2025-12-29 | 289.59x |
| 2025-12-26 | 292.44x |
| 2025-12-24 | 292.64x |
| 2025-12-23 | 292.27x |
| 2025-12-22 | 287.85x |
| 2025-12-19 | 283.28x |
| 2025-12-18 | 282.41x |
| 2025-12-17 | 294.32x |
| 2025-12-16 | 301.70x |
| 2025-12-15 | 312.61x |
| 2025-12-12 | 314.48x |
| 2025-12-11 | 304.08x |
| 2025-12-10 | 301.17x |
| 2025-12-09 | 291.70x |
| 2025-12-08 | 297.37x |
| 2025-12-05 | 295.36x |
| 2025-12-04 | 287.58x |
| 2025-12-03 | 283.35x |
| 2025-12-02 | 278.59x |
| 2025-12-01 | 281.91x |
| 2025-11-28 | 296.54x |
| 2025-11-26 | 296.77x |
| 2025-11-25 | 296.07x |
| 2025-11-24 | 288.79x |
| 2025-11-21 | 281.10x |
| 2025-11-20 | 277.08x |
| 2025-11-19 | 280.20x |
| 2025-11-18 | 277.71x |
| 2025-11-17 | 278.99x |
| 2025-11-14 | 278.45x |
| 2025-11-13 | 273.86x |
| 2025-11-12 | 279.26x |
| 2025-11-11 | 281.64x |
| 2025-11-10 | 273.82x |
| 2025-11-07 | 261.44x |
| 2025-11-06 | 204.77x |
| 2025-11-05 | 199.74x |
| 2025-11-04 | 196.08x |
| 2025-11-03 | 194.63x |
| 2025-10-31 | 201.70x |
| 2025-10-30 | 199.66x |
| 2025-10-29 | 196.59x |
| 2025-10-28 | 201.41x |
| 2025-10-27 | 192.77x |
| 2025-10-24 | 191.74x |
| 2025-10-23 | 189.44x |
| 2025-10-22 | 188.14x |
| 2025-10-21 | 192.11x |
| 2025-10-20 | 196.67x |
| 2025-10-17 | 198.73x |
| 2025-10-16 | 194.05x |
| 2025-10-15 | 199.21x |
| 2025-10-14 | 197.25x |
| 2025-10-13 | 203.16x |
| 2025-10-10 | 223.90x |
| 2025-10-09 | 171.03x |
| 2025-10-08 | 166.42x |
| 2025-10-07 | 166.87x |
| 2025-10-06 | 163.34x |
| 2025-10-03 | 165.17x |
| 2025-10-02 | 165.57x |
| 2025-10-01 | 162.97x |
| 2025-09-30 | 169.41x |
| 2025-09-29 | 165.99x |
| 2025-09-26 | 172.03x |
| 2025-09-25 | 164.83x |
| 2025-09-24 | 168.14x |
| 2025-09-23 | 165.78x |
| 2025-09-22 | 164.32x |
| 2025-09-19 | 158.20x |
| 2025-09-18 | 158.05x |
| 2025-09-17 | 150.31x |
| 2025-09-16 | 148.64x |
| 2025-09-15 | 148.09x |
| 2025-09-12 | 149.36x |
| 2025-09-11 | 151.53x |
| 2025-09-10 | 146.39x |
| 2025-09-09 | 148.03x |
| 2025-09-08 | 142.28x |
| 2025-09-05 | 153.78x |
| 2025-09-04 | 151.32x |
| 2025-09-03 | 147.37x |
| 2025-09-02 | 149.33x |
| 2025-08-29 | 149.86x |
| 2025-08-28 | 147.45x |
| 2025-08-27 | 156.17x |
| 2025-08-26 | 144.40x |
| 2025-08-25 | 144.11x |
| 2025-08-22 | 145.70x |
| 2025-08-21 | 141.89x |
| 2025-08-20 | 142.39x |
| 2025-08-19 | 142.44x |
| 2025-08-18 | 142.34x |
| 2025-08-15 | 141.97x |
| 2025-08-14 | 139.11x |
| 2025-08-13 | 143.69x |
| 2025-08-12 | 137.89x |
| 2025-08-11 | 135.82x |
| 2025-08-08 | 128.72x |
| 2025-08-07 | 128.43x |
| 2025-08-06 | 119.88x |
| 2025-08-05 | 119.95x |
| 2025-08-04 | 119.79x |
| 2025-08-01 | 119.79x |
| 2025-07-31 | 119.86x |
| 2025-07-30 | 121.61x |
| 2025-07-29 | 122.52x |
| 2025-07-28 | 125.41x |
| 2025-07-25 | 122.84x |
| 2025-07-24 | 119.58x |
| 2025-07-23 | 120.62x |
| 2025-07-22 | 122.47x |
| 2025-07-21 | 123.00x |
| 2025-07-18 | 123.60x |
| 2025-07-17 | 125.82x |
| 2025-07-16 | 126.29x |
| 2025-07-15 | 123.23x |
| 2025-07-14 | 123.02x |
| 2025-07-11 | 117.87x |
| 2025-07-10 | 117.47x |
| 2025-07-09 | 116.22x |
| 2025-07-08 | 110.23x |
| 2025-07-07 | 110.63x |
| 2025-07-03 | 113.36x |
| 2025-07-02 | 112.52x |
| 2025-07-01 | 111.41x |
| 2025-06-30 | 123.12x |
| 2025-06-27 | 124.09x |
| 2025-06-26 | 123.00x |
| 2025-06-25 | 121.20x |
| 2025-06-24 | 119.44x |
| 2025-06-23 | 118.70x |
| 2025-06-20 | 118.65x |
| 2025-06-18 | 119.99x |
| 2025-06-17 | 122.98x |
| 2025-06-16 | 121.71x |
| 2025-06-13 | 125.66x |
| 2025-06-12 | 125.55x |
| 2025-06-11 | 123.28x |
| 2025-06-10 | 125.66x |
| 2025-06-09 | 124.06x |
| 2025-06-06 | 121.06x |
| 2025-06-05 | 119.76x |
| 2025-06-04 | 114.47x |
| 2025-06-03 | 113.38x |
| 2025-06-02 | 111.28x |
| 2025-05-30 | 105.08x |
| 2025-05-29 | 105.33x |
| 2025-05-28 | 101.10x |
| 2025-05-27 | 102.67x |
| 2025-05-23 | 100.89x |
| 2025-05-22 | 101.47x |
| 2025-05-21 | 101.26x |
| 2025-05-20 | 103.09x |
| 2025-05-19 | 100.68x |
| 2025-05-16 | 98.18x |
| 2025-05-15 | 98.00x |
| 2025-05-14 | 96.52x |
| 2025-05-13 | 97.68x |
| 2025-05-12 | 99.99x |
| 2025-05-09 | 94.67x |
| 2025-05-08 | 96.87x |
| 2025-05-07 | 94.95x |
| 2025-05-06 | 10.69x |
| 2025-05-05 | 11.29x |
| 2025-05-02 | 11.61x |
| 2025-05-01 | 11.47x |
| 2025-04-30 | 11.69x |
| 2025-04-29 | 11.64x |
| 2025-04-28 | 11.32x |
| 2025-04-25 | 11.34x |
| 2025-04-24 | 11.44x |
| 2025-04-23 | 11.78x |
| 2025-04-22 | 11.70x |
| 2025-04-21 | 11.69x |
| 2025-04-17 | 11.81x |
| 2025-04-16 | 11.69x |
| 2025-04-15 | 11.99x |
| 2025-04-14 | 11.49x |
Showing the most recent 260 of 493 data points. The chart above shows the full history.
