Basis: Trailing twelve months (TTM), to the latest fiscal quarter end. Source: stored company filings and market data; unavailable inputs remain N/A.
Is the return on invested capital (ROIC) high or low?
The return on invested capital (ROIC) of -90.42% is 42% below its 5-year average of -63.88%, around the middle of its 5-year range (-149.02%–-8.83%).
As of the fiscal period ended Tuesday, June 30, 2026. 18.88% below its 12-month average of -76.06%.
Trailing-twelve-month return on invested capital at each fiscal quarter end; no daily interpolation. Q2 FY2026 (2026-06-30): -90.42%.
RETURN ON INVESTED CAPITAL (ROIC)
-90.42%
RETURN ON INVESTED CAPITAL (ROIC) AVG TTM
-76.06%
RETURN ON INVESTED CAPITAL (ROIC) AVG 3Y
-76.89%
RETURN ON INVESTED CAPITAL (ROIC) AVG 5Y
-63.88%
RETURN ON INVESTED CAPITAL (ROIC) AVG 10Y
N/A
RETURN ON INVESTED CAPITAL (ROIC) AVG 15Y
N/A
RETURN ON INVESTED CAPITAL (ROIC) AVG 20Y
N/A
CURRENT VS TTM AVG
-18.88%
CURRENT VS 3Y AVG
-17.60%
CURRENT VS 5Y AVG
-41.54%
CURRENT VS 10Y AVG
N/A
CURRENT VS 15Y AVG
N/A
CURRENT VS 20Y AVG
N/A
SECTOR MEDIAN · HEALTHCARE
-35.64%
median of 838 covered companies
CURRENT VS SECTOR MEDIAN
-153.66%
vs the sector median at left
Prime Medicine, Inc.
Market Cap
$635.18M
Return on Invested Capital (ROIC)
-90.42%
TTM Avg
-76.06%
3Y Avg
-76.89%
5Y Avg
-63.88%
Market Cap
$637.69M
Return on Invested Capital (ROIC)
-42.02%
TTM Avg
-66.01%
3Y Avg
-48.82%
5Y Avg
-55.42%
Market Cap
$629.92M
Return on Invested Capital (ROIC)
12.93%
TTM Avg
-31.02%
3Y Avg
-34.46%
5Y Avg
-44.99%
Market Cap
$641.50M
Return on Invested Capital (ROIC)
-17.48%
TTM Avg
-24.56%
3Y Avg
-18.89%
5Y Avg
-16.21%
Market Cap
$625.86M
Return on Invested Capital (ROIC)
-49.73%
TTM Avg
-57.30%
3Y Avg
-49.74%
5Y Avg
-42.74%
Market Cap
$616.72M
Return on Invested Capital (ROIC)
-26.94%
TTM Avg
-40.40%
3Y Avg
-38.31%
5Y Avg
-45.27%
Market Cap
$655.05M
Return on Invested Capital (ROIC)
-31.32%
TTM Avg
-38.51%
3Y Avg
-38.51%
5Y Avg
-38.51%
Market Cap
$659.73M
Return on Invested Capital (ROIC)
-47.96%
TTM Avg
-47.20%
3Y Avg
-41.20%
5Y Avg
-37.18%
Market Cap
$664.48M
Return on Invested Capital (ROIC)
1.97%
TTM Avg
18.16%
3Y Avg
11.04%
5Y Avg
1.26%
| NAME | MARKET CAP | RETURN ON INVESTED CAPITAL (ROIC) | TTM | 3Y | 5Y |
|---|---|---|---|---|---|
| Prime Medicine, Inc. (PRME) | $635.18M | -90.42% | -76.06% | -76.89% | -63.88% |
| Aura Biosciences, Inc. (AURA)vs › | $637.69M | -42.02% | -66.01% | -48.82% | -55.42% |
| Zevra Therapeutics, Inc. (ZVRA)vs › | $629.92M | 12.93% | -31.02% | -34.46% | -44.99% |
| OmniAb, Inc. (OABI)vs › | $641.50M | -17.48% | -24.56% | -18.89% | -16.21% |
| SOPHiA GENETICS S.A. (SOPH)vs › | $625.86M | -49.73% | -57.30% | -49.74% | -42.74% |
| Climb Bio, Inc. (CLYM)vs › | $616.72M | -26.94% | -40.40% | -38.31% | -45.27% |
| Starling Oncology, Inc. (STLN)vs › | $655.05M | -31.32% | -38.51% | -38.51% | -38.51% |
| ArriVent BioPharma, Inc. (AVBP)vs › | $659.73M | -47.96% | -47.20% | -41.20% | -37.18% |
| MiMedx Group, Inc. (MDXG)vs › | $664.48M | 1.97% | 18.16% | 11.04% | 1.26% |
| Annexon, Inc. (ANNX)vs › | $667.69M | -101.43% | -70.16% | -61.78% | -52.46% |
ROIC
-90.4%
ROE
-472.0%
ROIC = NOPAT / Invested Capital, where NOPAT = Operating Income × (1 − effective tax rate) and Invested Capital = Total Assets − (Current Liabilities − Short-Term Debt)
Return on invested capital measures the after-tax operating return a company earns on the capital invested in the business. TGMCharts computes it from reported statements: trailing-twelve-month operating income after tax, over invested capital at the latest balance sheet — total assets less the non-interest-bearing current liabilities (payables, accruals, deferred revenue) that fund them; short-term debt stays in the capital base. The tax rate is the period's own effective rate (income tax ÷ pretax income), capped at 45%; when pretax income is zero or negative, or the tax line is a net benefit, no tax is deducted — the operating figure is shown untaxed rather than adjusted by an assumed rate. Not shown for banks, insurers or funds.
Expanded definitions: Investopedia, Wikipedia, Corporate Finance Institute
| DATE | RETURN ON INVESTED CAPITAL (ROIC) |
|---|---|
| 2026-06-30 | -90.42% |
| 2026-03-31 | -79.95% |
| 2025-12-31 | -68.25% |
| 2025-09-30 | -58.28% |
| 2025-06-30 | -83.39% |
| 2025-03-31 | -70.27% |
| 2024-12-31 | -78.01% |
| 2024-09-30 | -76.73% |
| 2024-06-30 | -93.54% |
| 2024-03-31 | -74.27% |
| 2023-12-31 | -149.02% |
| 2023-09-30 | -87.81% |
| 2023-06-30 | -61.72% |
| 2023-03-31 | -46.64% |
| 2022-12-31 | -34.94% |
| 2022-09-30 | -71.45% |
| 2022-06-30 | -52.16% |
| 2022-03-31 | -42.48% |
| 2021-12-31 | -34.64% |
| 2021-09-30 | -8.83% |
