Annexon, Inc. (ANNX) vs Prime Medicine, Inc. (PRME)
A side-by-side comparison of Annexon, Inc. and Prime Medicine, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
ANNX
Annexon, Inc.
$4.07HealthcareDelayed quote: Oct 6, 2026, 1:55 PM EDT
PRME
Prime Medicine, Inc.
$3.49HealthcareDelayed quote: Oct 6, 2026, 1:55 PM EDT
Total return — ANNX vs PRME
growth of $100 · dividends reinvested · last 4yANNX -17.8% (-4.8%/yr)PRME -79.1% (-32.4%/yr)ANNX compounded faster over this window
ANNX PRME
ANNX vs PRME: by the numbers
- •ANNX is the larger company ($666M vs $629M market cap).
- •Both run net losses; ANNX's is the smaller (0.00% vs -4613.11% net margin).
Metrics side by side
Valuation
| Metric | ANNX | PRME |
|---|---|---|
| P/S ratio | N/A | 154.54 |
| P/B ratio | 3.58 | 15.81 |
Profitability
| Metric | ANNX | PRME |
|---|---|---|
| Gross margin | 0.00% | -58.05% |
| Operating margin | 0.00% | -4498.06% |
| Net margin | 0.00% | -4613.11% |
| ROE | -108.93% | -471.98% |
| ROIC | -101.43% | -90.42% |
Growth (annualized)
| Metric | ANNX | PRME |
|---|---|---|
| Revenue CAGR (5Y) | N/A | -2.32% |
| Total return CAGR (5Y) | -26.29% | N/A |
Go deeper
Dig into the metrics
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.