MiMedx Group, Inc. (MDXG) vs Prime Medicine, Inc. (PRME)

A side-by-side comparison of MiMedx Group, Inc. and Prime Medicine, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

Compare

Total return — MDXG vs PRME

growth of $100 · dividends reinvested · last 4y
MDXG +57.4% (+12.0%/yr)PRME -79.1% (-32.4%/yr)MDXG compounded faster over this window
Log scale — wide-divergence pair
1101001kStart $1002023202420252026$157$21
MDXG PRME

MDXG vs PRME: by the numbers

  • •MDXG is the larger company ($673M vs $632M market cap).
  • •MDXG is profitable (1.76% net margin) while PRME runs a net loss (-4613.11%).
  • •MDXG grew revenue faster over the past five years (6.36% vs -2.32% CAGR).

Metrics side by side

Valuation

MetricMDXGPRME
P/E ratio115.50N/A
P/S ratio1.90155.21
P/B ratio3.1215.88
EV / EBITDA26.41N/A
FCF yield6.03%N/A

Profitability

MetricMDXGPRME
Gross margin78.85%-58.05%
Operating margin15.26%-4498.06%
Net margin1.76%-4613.11%
ROE2.89%-471.98%
ROIC1.97%-90.42%

Growth (annualized)

MetricMDXGPRME
Revenue CAGR (5Y)6.36%-2.32%
Total return CAGR (5Y)-4.94%N/A

Frequently asked

Which has grown faster, MDXG or PRME?
Over the past five years, MDXG grew revenue faster — MDXG at a 6.36% CAGR versus PRME at -2.32%.
Is MDXG or PRME more profitable?
MDXG runs the higher net margin — MDXG at 1.76% versus PRME at -4613.11%.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.