Prime Medicine (PRME) Metrics: History & Chart

Prime Medicine, Inc.(PRME)

Biotechnology · Cambridge, MA

$3.47+0.25 (+7.94%)

Delayed quote: Oct 6, 2026, 1:15 PM EDT

About Prime Medicine, Inc.

Prime Medicine, Inc. operates as a biotechnology firm, dedicated to delivering genetic therapies for various diseases by strategically employing advanced gene editing technology. Central to their platform is the "Prime Editor" system, which combines a unique Prime Editor protein—a hybrid composed of a Cas protein and a reverse transcriptase enzyme—with a specialized pegRNA molecule. This pegRNA plays a crucial role by both guiding the Prime Editor to a precise location within the genome and providing the essential template for introducing the desired modification to the target DNA sequence. The company, founded in 2019, maintains its headquarters in Cambridge, Massachusetts.

Cambridge, MA

146 employees

www.primemedicine.com

Healthcare / Biotechnology

Sector: Healthcare
Industry: Biotechnology
CEO: Allan Reine

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Third-Party DCF Estimate (FMP)	N/A
Price Gap vs Third-Party Estimate	N/A

7D Total Return	+11.46%
30D Total Return	-13.24%
YTD Total Return	-7.49%
1Y Total Return	-49.21%
3Y Total Return	-63.90%
5Y Total Return	N/A
10Y Total Return	N/A
15Y Total Return	N/A
20Y Total Return	N/A

2026	-7.49%
2025	+18.84%
2024	-67.04%
2023	-52.31%
2022	N/A
2021	N/A

CAGR TTM	-49.04%
CAGR 3Y	-28.79%
CAGR 5Y	N/A
CAGR 10Y	N/A
CAGR 15Y	N/A
CAGR 20Y	N/A

PE Ratio	N/A
PE Ratio Avg TTM	N/A
PE Ratio Avg 3Y	N/A
Current VS TTM Avg	N/A
Current VS 3Y Avg	N/A
Current VS 5Y Avg	N/A

All Metrics

PRME Valuation Metrics

PRME Stock Price Metrics

PRME Dividend Metrics

PRME Growth Rate Metrics

PRME Discounted Cash Flow Metrics

PRME Returns By Period

PRME Yearly Returns

PRME Average Annual Returns By Period (CAGR)

PRME Revenue Metrics

PRME PE Ratio Metrics

PRME PS Ratio Metrics

PRME PB Ratio Metrics

PRME Price to Free Cash Flow Ratio Metrics

PRME Debt to Equity Ratio Metrics

PRME PEG Ratio Metrics

PRME FCF Yield

PRME Earnings Yield

PRME EBITDA Yield

PRME OCF Yield

PRME EV/EBIT Ratio Metrics

PRME EV/EBITDA Ratio Metrics

PRME EV/Assets Ratio Metrics

PRME EV/Sales Ratio Metrics

PRME Current Ratio Metrics

PRME Quick Ratio Metrics

PRME ROIC Metrics

PRME Return on Assets Metrics

PRME Return on Equity Metrics

PRME Net Profit Margin Metrics

PRME Gross Profit Margin Metrics

PRME Tax Rate Metrics

PS Ratio	139.67
PS Ratio Avg TTM	124.10
PS Ratio Avg 3Y	275.62
Current VS TTM Avg	+12.55%
Current VS 3Y Avg	-49.33%
Current VS 5Y Avg	-49.33%

PB Ratio	14.29
PB Ratio Avg TTM	7.32
PB Ratio Avg 3Y	3.68
Current VS TTM Avg	+95.27%
Current VS 3Y Avg	+288.22%
Current VS 5Y Avg	+285.92%

PFCF Ratio	N/A
PFCF Ratio Avg TTM	N/A
PFCF Ratio Avg 3Y	N/A
Current VS TTM Avg	N/A
Current VS 3Y Avg	N/A
Current VS 5Y Avg	N/A

Debt/Equity Ratio	2.83
Debt/Equity Ratio Avg TTM	1.60
Debt/Equity Ratio Avg 3Y	0.62
Current VS TTM Avg	+77.05%
Current VS 3Y Avg	+354.60%
Current VS 5Y Avg	+774.18%

PEG Ratio	N/A
PEG Ratio Avg TTM	N/A
PEG Ratio Avg 3Y	N/A
Current VS TTM Avg	N/A
Current VS 3Y Avg	N/A
Current VS 5Y Avg	N/A

FCF Yield	N/A
FCF Yield Avg TTM	N/A
FCF Yield Avg 3Y	N/A
Current VS TTM Avg	N/A
Current VS 3Y Avg	N/A
Current VS 5Y Avg	N/A

Earnings Yield	N/A
Earnings Yield Avg TTM	N/A
Earnings Yield Avg 3Y	N/A
Current VS TTM Avg	N/A
Current VS 3Y Avg	N/A
Current VS 5Y Avg	N/A

EBITDA Yield	N/A
EBITDA Yield Avg TTM	N/A
EBITDA Yield Avg 3Y	N/A
Current VS TTM Avg	N/A
Current VS 3Y Avg	N/A
Current VS 5Y Avg	N/A

OCF Yield	N/A
OCF Yield Avg TTM	N/A
OCF Yield Avg 3Y	N/A
Current VS TTM Avg	N/A
Current VS 3Y Avg	N/A
Current VS 5Y Avg	N/A

Ev/Ebit Ratio	N/A
Ev/Ebit Ratio Avg TTM	N/A
Ev/Ebit Ratio Avg 3Y	N/A
Current VS TTM Avg	N/A
Current VS 3Y Avg	N/A
Current VS 5Y Avg	N/A

Ev/Ebitda Ratio	N/A
Ev/Ebitda Ratio Avg TTM	N/A
Ev/Ebitda Ratio Avg 3Y	N/A
Current VS TTM Avg	N/A
Current VS 3Y Avg	N/A
Current VS 5Y Avg	N/A

Ev/Assets Ratio	2.55
Ev/Assets Ratio Avg TTM	2.05
Ev/Assets Ratio Avg 3Y	1.91
Current VS TTM Avg	+24.23%
Current VS 3Y Avg	+33.58%
Current VS 5Y Avg	+20.34%

Ev/Sales Ratio	155.64
Ev/Sales Ratio Avg TTM	135.87
Ev/Sales Ratio Avg 3Y	185.91
Current VS TTM Avg	+14.55%
Current VS 3Y Avg	-16.28%
Current VS 5Y Avg	-16.28%

Current Ratio	3.05
Current Ratio Avg TTM	4.37
Current Ratio Avg 3Y	5.44
Current VS TTM Avg	-30.13%
Current VS 3Y Avg	-43.82%
Current VS 5Y Avg	-47.90%

Quick Ratio	3.05
Quick Ratio Avg TTM	4.37
Quick Ratio Avg 3Y	5.44
Current VS TTM Avg	-30.13%
Current VS 3Y Avg	-43.82%
Current VS 5Y Avg	-47.90%

ROIC	(90.42%)
ROIC Avg 3Y	(76.89%)
ROIC Avg 5Y	(63.88%)
Current VS 3Y Avg	-17.60%
Current VS 5Y Avg	-41.54%
Current VS 10Y Avg	-41.54%

ROA	(75.45%)
ROA Avg TTM	(15.80%)
ROA Avg 3Y	(16.43%)
Current VS TTM Avg	-377.49%
Current VS 3Y Avg	-359.35%
Current VS 5Y Avg	-385.95%

ROE	(471.98%)
ROE Avg TTM	(269.28%)
ROE Avg 3Y	(134.25%)
Current VS TTM Avg	-75.27%
Current VS 3Y Avg	-251.56%
Current VS 5Y Avg	-353.96%

Net Profit Margin	(4613.11%)
Net Profit Margin Avg TTM	(4746.40%)
Net Profit Margin Avg 3Y	(3081.70%)
Current VS TTM Avg	+2.81%
Current VS 3Y Avg	-49.69%
Current VS 5Y Avg	-149.49%

Gross Profit Margin	(58.05%)
Gross Pft Margin Avg TTM	(695.00%)
Gross Pft Margin Avg 3Y	16.12%
Current VS TTM Avg	+91.65%
Current VS 3Y Avg	-460.00%
Current VS 5Y Avg	N/A

Tax Rate	64.48%
Tax Rate Avg 3Y	N/A
Tax Rate Avg 5Y	N/A
Current VS 3Y Avg	N/A
Current VS 5Y Avg	N/A
Current VS 10Y Avg	N/A