Basis: Current FMP quote-based enterprise value / four-quarter operating income plus matched D&A. Source: stored company filings and market data; unavailable inputs remain N/A.
Is the EV/EBITDA ratio high or low?
The EV/EBITDA ratio of 45.64x is in line with its estimated 2-year average of 44.91x, near the low end of its estimated 2-year range (25.43x–164.20x).
As of 2026-10-06T16:17:28.247Z. 0.13% above its estimated 12-month average of 45.58x.
Calculation as of: 2026-10-06T16:17:28.247Z.
Quote observation: 2026-10-06T16:15:15.000Z. Amounts in USD. The price header may show a later quote.
FMP input reference: ea97e6614670234c5dbfdf3bc7583d3b35e8d285e8978cbe73844bd7e5ba46ca
Historical values estimate market capitalization from statement-period weighted shares. Comparisons with the current quote-based value are approximate. Only filing versions delivered by FMP are available for the historical calculation. Historical series through 2026-10-05.
Historical values estimate market capitalization from statement-period weighted shares. Comparisons with the current quote-based value are approximate. Only filing versions delivered by FMP are available for the historical calculation.
EV/EBITDA RATIO
45.64x
EV/EBITDA RATIO AVG TTM
45.58x
EV/EBITDA RATIO AVG 3Y
N/A
EV/EBITDA RATIO AVG 5Y
N/A
EV/EBITDA RATIO AVG 10Y
N/A
EV/EBITDA RATIO AVG 15Y
N/A
EV/EBITDA RATIO AVG 20Y
N/A
CURRENT VS TTM AVG
+0.13%
CURRENT VS 3Y AVG
N/A
CURRENT VS 5Y AVG
N/A
CURRENT VS 10Y AVG
N/A
CURRENT VS 15Y AVG
N/A
CURRENT VS 20Y AVG
N/A
SECTOR MEDIAN · HEALTHCARE
15.70x
median of 197 covered companies
CURRENT VS SECTOR MEDIAN
+190.70%
vs the sector median at left
Krystal Biotech, Inc.
Market Cap
$9.75B
EV/EBITDA Ratio
45.64x
TTM Avg
45.58x
3Y Avg
N/A
5Y Avg
N/A
Market Cap
$9.71B
EV/EBITDA Ratio
12.30x
TTM Avg
11.82x
3Y Avg
11.96x
5Y Avg
11.68x
Market Cap
$9.98B
EV/EBITDA Ratio
27.88x
TTM Avg
22.27x
3Y Avg
19.88x
5Y Avg
21.50x
Market Cap
$10.01B
EV/EBITDA Ratio
19.36x
TTM Avg
10.46x
3Y Avg
9.60x
5Y Avg
10.77x
Market Cap
$10.09B
EV/EBITDA Ratio
68.51x
TTM Avg
66.53x
3Y Avg
81.35x
5Y Avg
68.10x
Market Cap
$10.12B
EV/EBITDA Ratio
20.81x
TTM Avg
24.30x
3Y Avg
24.10x
5Y Avg
21.70x
Market Cap
$9.32B
EV/EBITDA Ratio
30.99x
TTM Avg
23.19x
3Y Avg
21.87x
5Y Avg
21.39x
| NAME | MARKET CAP | EV/EBITDA RATIO | TTM | 3Y | 5Y |
|---|---|---|---|---|---|
| Krystal Biotech, Inc. (KRYS) | $9.75B | 45.64x | 45.58x | N/A | N/A |
| Henry Schein, Inc. (HSIC)vs › | $9.71B | 12.30x | 11.82x | 11.96x | 11.68x |
| Bio-Rad Laboratories, Inc. (BIO)vs › | $9.98B | 27.88x | 22.27x | 19.88x | 21.50x |
| Molina Healthcare, Inc. (MOH)vs › | $10.01B | 19.36x | 10.46x | 9.60x | 10.77x |
| Vaxcyte, Inc. (PCVX)vs › | $9.40B | N/A | N/A | N/A | N/A |
| Repligen Corporation (RGEN)vs › | $10.09B | 68.51x | 66.53x | 81.35x | 68.10x |
| Insulet Corp. (PODD)vs › | $9.40B | 15.79x | 28.49x | 45.32x | 85.61x |
| The Ensign Group, Inc. (ENSG)vs › | $10.12B | 20.81x | 24.30x | 24.10x | 21.70x |
| Bruker Corporation (BRKR)vs › | $9.32B | 30.99x | 23.19x | 21.87x | 21.39x |
| Align Technology, Inc. (ALGN)vs › | $10.23B | 11.47x | 14.07x | 18.68x | 23.02x |
At 45.6, EV/EBITDA is near its estimated 2-year median — higher than 45% of readings in its estimated 2-year history.
Historical values estimate market capitalization from statement-period weighted shares. Comparisons with the current quote-based value are approximate. Only filing versions delivered by FMP are available for the historical calculation.
estimated 2-year low
25.4
median
46.9
estimated 2-year high
164.2
EV/EBITDA = Enterprise Value / EBITDA (TTM)
Enterprise value to EBITDA is a capital-structure-neutral valuation multiple, useful for comparing companies with different debt levels and tax rates.
Expanded definitions: Investopedia, Wikipedia, Corporate Finance Institute
| DATE | EV/EBITDA RATIO |
|---|---|
| 2026-10-05 | 48.18x |
| 2026-10-02 | 46.29x |
| 2026-10-01 | 46.75x |
| 2026-09-30 | 47.84x |
| 2026-09-29 | 48.21x |
| 2026-09-28 | 48.51x |
| 2026-09-25 | 49.83x |
| 2026-09-24 | 49.70x |
| 2026-09-23 | 49.21x |
| 2026-09-22 | 50.58x |
| 2026-09-21 | 48.03x |
| 2026-09-18 | 48.45x |
| 2026-09-17 | 48.76x |
| 2026-09-16 | 48.45x |
| 2026-09-15 | 48.45x |
| 2026-09-14 | 48.96x |
| 2026-09-11 | 50.00x |
| 2026-09-10 | 49.78x |
| 2026-09-09 | 50.17x |
| 2026-09-08 | 50.64x |
| 2026-09-04 | 51.69x |
| 2026-09-03 | 53.67x |
| 2026-09-02 | 53.34x |
| 2026-09-01 | 52.53x |
| 2026-08-31 | 51.86x |
| 2026-08-28 | 50.67x |
| 2026-08-27 | 51.57x |
| 2026-08-26 | 51.92x |
| 2026-08-25 | 51.38x |
| 2026-08-24 | 49.21x |
| 2026-08-21 | 49.94x |
| 2026-08-20 | 48.51x |
| 2026-08-19 | 49.45x |
| 2026-08-18 | 47.88x |
| 2026-08-17 | 48.31x |
| 2026-08-14 | 47.79x |
| 2026-08-13 | 47.20x |
| 2026-08-12 | 47.88x |
| 2026-08-11 | 47.01x |
| 2026-08-10 | 47.69x |
| 2026-08-07 | 46.92x |
| 2026-08-06 | 46.36x |
| 2026-08-05 | 46.82x |
| 2026-08-04 | 46.67x |
| 2026-08-03 | 48.76x |
| 2026-07-31 | 53.46x |
| 2026-07-30 | 57.69x |
| 2026-07-29 | 57.11x |
| 2026-07-28 | 57.26x |
| 2026-07-27 | 55.22x |
| 2026-07-24 | 52.49x |
| 2026-07-23 | 51.22x |
| 2026-07-22 | 52.75x |
| 2026-07-21 | 53.12x |
| 2026-07-20 | 53.15x |
| 2026-07-17 | 55.72x |
| 2026-07-16 | 53.57x |
| 2026-07-15 | 54.96x |
| 2026-07-14 | 53.18x |
| 2026-07-13 | 57.13x |
| 2026-07-10 | 57.52x |
| 2026-07-09 | 58.42x |
| 2026-07-08 | 59.10x |
| 2026-07-07 | 57.98x |
| 2026-07-06 | 58.98x |
| 2026-07-02 | 59.05x |
| 2026-07-01 | 58.47x |
| 2026-06-30 | 58.49x |
| 2026-06-29 | 59.55x |
| 2026-06-26 | 58.58x |
| 2026-06-25 | 56.56x |
| 2026-06-24 | 54.53x |
| 2026-06-23 | 53.31x |
| 2026-06-22 | 53.84x |
| 2026-06-18 | 54.60x |
| 2026-06-17 | 53.55x |
| 2026-06-16 | 50.54x |
| 2026-06-15 | 50.77x |
| 2026-06-12 | 49.65x |
| 2026-06-11 | 50.24x |
| 2026-06-10 | 48.74x |
| 2026-06-09 | 48.30x |
| 2026-06-08 | 46.99x |
| 2026-06-05 | 46.86x |
| 2026-06-04 | 47.98x |
| 2026-06-03 | 47.00x |
| 2026-06-02 | 45.58x |
| 2026-06-01 | 46.38x |
| 2026-05-29 | 48.18x |
| 2026-05-28 | 48.39x |
| 2026-05-27 | 47.79x |
| 2026-05-26 | 47.14x |
| 2026-05-22 | 46.61x |
| 2026-05-21 | 47.39x |
| 2026-05-20 | 47.03x |
| 2026-05-19 | 45.59x |
| 2026-05-18 | 45.34x |
| 2026-05-15 | 47.73x |
| 2026-05-14 | 49.38x |
| 2026-05-13 | 48.77x |
| 2026-05-12 | 48.39x |
| 2026-05-11 | 48.82x |
| 2026-05-08 | 47.64x |
| 2026-05-07 | 46.15x |
| 2026-05-06 | 44.89x |
| 2026-05-05 | 44.16x |
| 2026-05-04 | 48.30x |
| 2026-05-01 | 44.57x |
| 2026-04-30 | 43.90x |
| 2026-04-29 | 43.49x |
| 2026-04-28 | 45.15x |
| 2026-04-27 | 45.77x |
| 2026-04-24 | 45.73x |
| 2026-04-23 | 44.93x |
| 2026-04-22 | 46.34x |
| 2026-04-21 | 45.75x |
| 2026-04-20 | 46.44x |
| 2026-04-17 | 46.03x |
| 2026-04-16 | 44.22x |
| 2026-04-15 | 45.02x |
| 2026-04-14 | 45.28x |
| 2026-04-13 | 44.82x |
| 2026-04-10 | 43.32x |
| 2026-04-09 | 43.20x |
| 2026-04-08 | 44.25x |
| 2026-04-07 | 44.21x |
| 2026-04-06 | 43.82x |
| 2026-04-02 | 43.66x |
| 2026-04-01 | 43.30x |
| 2026-03-31 | 43.19x |
| 2026-03-30 | 41.16x |
| 2026-03-27 | 40.89x |
| 2026-03-26 | 41.96x |
| 2026-03-25 | 42.59x |
| 2026-03-24 | 41.19x |
| 2026-03-23 | 41.72x |
| 2026-03-20 | 42.01x |
| 2026-03-19 | 43.14x |
| 2026-03-18 | 41.86x |
| 2026-03-17 | 42.84x |
| 2026-03-16 | 41.74x |
| 2026-03-13 | 41.22x |
| 2026-03-12 | 41.94x |
| 2026-03-11 | 42.60x |
| 2026-03-10 | 43.69x |
| 2026-03-09 | 43.25x |
| 2026-03-06 | 42.37x |
| 2026-03-05 | 43.55x |
| 2026-03-04 | 44.39x |
| 2026-03-03 | 44.17x |
| 2026-03-02 | 43.28x |
| 2026-02-27 | 46.28x |
| 2026-02-26 | 46.41x |
| 2026-02-25 | 45.72x |
| 2026-02-24 | 44.73x |
| 2026-02-23 | 46.10x |
| 2026-02-20 | 43.82x |
| 2026-02-19 | 43.97x |
| 2026-02-18 | 47.65x |
| 2026-02-17 | 49.85x |
| 2026-02-13 | 47.78x |
| 2026-02-12 | 46.66x |
| 2026-02-11 | 47.10x |
| 2026-02-10 | 46.74x |
| 2026-02-09 | 47.09x |
| 2026-02-06 | 47.11x |
| 2026-02-05 | 46.19x |
| 2026-02-04 | 46.46x |
| 2026-02-03 | 48.35x |
| 2026-02-02 | 48.84x |
| 2026-01-30 | 48.29x |
| 2026-01-29 | 48.31x |
| 2026-01-28 | 47.14x |
| 2026-01-27 | 47.95x |
| 2026-01-26 | 48.20x |
| 2026-01-23 | 48.71x |
| 2026-01-22 | 50.08x |
| 2026-01-21 | 49.52x |
| 2026-01-20 | 47.49x |
| 2026-01-16 | 49.34x |
| 2026-01-15 | 48.79x |
| 2026-01-14 | 50.56x |
| 2026-01-13 | 50.59x |
| 2026-01-12 | 47.00x |
| 2026-01-09 | 45.06x |
| 2026-01-08 | 42.79x |
| 2026-01-07 | 42.33x |
| 2026-01-06 | 42.88x |
| 2026-01-05 | 42.03x |
| 2026-01-02 | 42.43x |
| 2025-12-31 | 42.36x |
| 2025-12-30 | 42.61x |
| 2025-12-29 | 43.66x |
| 2025-12-26 | 43.38x |
| 2025-12-24 | 43.22x |
| 2025-12-23 | 43.60x |
| 2025-12-22 | 42.92x |
| 2025-12-19 | 41.32x |
| 2025-12-18 | 39.98x |
| 2025-12-17 | 40.42x |
| 2025-12-16 | 40.91x |
| 2025-12-15 | 41.72x |
| 2025-12-12 | 42.02x |
| 2025-12-11 | 42.41x |
| 2025-12-10 | 41.13x |
| 2025-12-09 | 40.21x |
| 2025-12-08 | 40.10x |
| 2025-12-05 | 40.11x |
| 2025-12-04 | 37.91x |
| 2025-12-03 | 37.09x |
| 2025-12-02 | 36.66x |
| 2025-12-01 | 36.67x |
| 2025-11-28 | 37.19x |
| 2025-11-26 | 37.32x |
| 2025-11-25 | 37.00x |
| 2025-11-24 | 36.63x |
| 2025-11-21 | 36.11x |
| 2025-11-20 | 34.69x |
| 2025-11-19 | 34.67x |
| 2025-11-18 | 34.79x |
| 2025-11-17 | 35.42x |
| 2025-11-14 | 35.04x |
| 2025-11-13 | 34.15x |
| 2025-11-12 | 34.48x |
| 2025-11-11 | 34.47x |
| 2025-11-10 | 33.84x |
| 2025-11-07 | 33.55x |
| 2025-11-06 | 33.92x |
| 2025-11-05 | 33.90x |
| 2025-11-04 | 34.52x |
| 2025-11-03 | 38.07x |
| 2025-10-31 | 38.00x |
| 2025-10-30 | 36.28x |
| 2025-10-29 | 35.46x |
| 2025-10-28 | 36.40x |
| 2025-10-27 | 36.45x |
| 2025-10-24 | 35.68x |
| 2025-10-23 | 35.74x |
| 2025-10-22 | 35.74x |
| 2025-10-21 | 36.63x |
| 2025-10-20 | 37.69x |
| 2025-10-17 | 36.51x |
| 2025-10-16 | 36.13x |
| 2025-10-15 | 37.08x |
| 2025-10-14 | 36.07x |
| 2025-10-13 | 35.39x |
| 2025-10-10 | 34.72x |
| 2025-10-09 | 36.21x |
| 2025-10-08 | 35.89x |
| 2025-10-07 | 35.04x |
| 2025-10-06 | 34.54x |
| 2025-10-03 | 35.11x |
| 2025-10-02 | 34.77x |
| 2025-10-01 | 34.34x |
| 2025-09-30 | 33.71x |
| 2025-09-29 | 33.76x |
| 2025-09-26 | 31.93x |
| 2025-09-25 | 30.57x |
| 2025-09-24 | 30.75x |
| 2025-09-23 | 31.35x |
Showing the most recent 260 of 479 data points. The chart above shows the full history.