Krystal Biotech (KRYS) Metrics: History & Chart

Krystal Biotech, Inc.(KRYS)

Biotechnology · Pittsburgh, PA

$326.72-8.14 (-2.43%)

Delayed quote: Oct 6, 2026, 3:10 PM EDT

About Krystal Biotech, Inc.

Krystal Biotech, Inc. is a clinical-stage biotechnology company focused on developing redosable gene therapies to address severe orphan diseases across the United States. Its most advanced therapeutic candidate, beremagene geperpavec (B-VEC), is currently undergoing Phase III clinical evaluation for the treatment of dystrophic epidermolysis bullosa. The company's pipeline also includes several other promising programs: KB105 is in Phase I/II clinical trials for patients suffering from deficient autosomal recessive congenital ichthyosis; KB301 is also in Phase I/II development, aiming to ameliorate wrinkles and other signs of aging or damaged skin. Additionally, Krystal Biotech is conducting preclinical research on KB407 for cystic fibrosis and KB104 for Netherton syndrome. In its earlier discovery phase, the company is exploring candidates such as KB5xx for chronic skin conditions and multiple KB3xx programs targeting aesthetic dermatological concerns. Krystal Biotech, Inc. was established in 2015 and is based in Pittsburgh, Pennsylvania.

Pittsburgh, PA

295 employees

www.krystalbio.com

Healthcare / Biotechnology

Sector: Healthcare
Industry: Biotechnology
CEO: Krish S. Krishnan

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Third-Party DCF Estimate (FMP)	$456.92
Price Gap vs Third-Party Estimate	+36.46%

7D Total Return	-0.66%
30D Total Return	-6.53%
YTD Total Return	+35.82%
1Y Total Return	+82.62%
3Y Total Return	+191.88%
5Y Total Return	+525.06%
10Y Total Return	N/A
15Y Total Return	N/A
20Y Total Return	N/A

2026	+35.82%
2025	+57.37%
2024	+26.28%
2023	+56.60%
2022	+13.25%
2021	+16.58%

CAGR TTM	+82.10%
CAGR 3Y	+42.90%
CAGR 5Y	+44.28%
CAGR 10Y	N/A
CAGR 15Y	N/A
CAGR 20Y	N/A

PE Ratio	41.96
PE Ratio Avg TTM	40.22
PE Ratio Avg 3Y	53.73
Current VS TTM Avg	+4.33%
Current VS 3Y Avg	-21.90%
Current VS 5Y Avg	-21.90%

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KRYS Valuation Metrics

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KRYS Growth Rate Metrics

KRYS Discounted Cash Flow Metrics

KRYS Returns By Period

KRYS Yearly Returns

KRYS Average Annual Returns By Period (CAGR)

KRYS Revenue Metrics

KRYS PE Ratio Metrics

KRYS PS Ratio Metrics

KRYS PB Ratio Metrics

KRYS Price to Free Cash Flow Ratio Metrics

KRYS Debt to Equity Ratio Metrics

KRYS PEG Ratio Metrics

KRYS FCF Yield

KRYS Earnings Yield

KRYS EBITDA Yield

KRYS OCF Yield

KRYS EV/EBIT Ratio Metrics

KRYS EV/EBITDA Ratio Metrics

KRYS EV/Assets Ratio Metrics

KRYS EV/Sales Ratio Metrics

KRYS Current Ratio Metrics

KRYS Quick Ratio Metrics

KRYS ROIC Metrics

KRYS Return on Assets Metrics

KRYS Return on Equity Metrics

KRYS Net Profit Margin Metrics

KRYS Gross Profit Margin Metrics

KRYS Tax Rate Metrics

PS Ratio	23.31
PS Ratio Avg TTM	21.26
PS Ratio Avg 3Y	25.61
Current VS TTM Avg	+9.63%
Current VS 3Y Avg	-8.97%
Current VS 5Y Avg	-8.97%

PB Ratio	7.55
PB Ratio Avg TTM	6.94
PB Ratio Avg 3Y	5.92
Current VS TTM Avg	+8.87%
Current VS 3Y Avg	+27.61%
Current VS 5Y Avg	+49.37%

PFCF Ratio	39.82
PFCF Ratio Avg TTM	42.26
PFCF Ratio Avg 3Y	38.60
Current VS TTM Avg	-5.76%
Current VS 3Y Avg	+3.17%
Current VS 5Y Avg	+3.17%

Debt/Equity Ratio	0.01
Debt/Equity Ratio Avg TTM	0.01
Debt/Equity Ratio Avg 3Y	0.01
Current VS TTM Avg	-16.43%
Current VS 3Y Avg	-28.49%
Current VS 5Y Avg	-46.49%

PEG Ratio	N/A
PEG Ratio Avg TTM	N/A
PEG Ratio Avg 3Y	N/A
Current VS TTM Avg	N/A
Current VS 3Y Avg	N/A
Current VS 5Y Avg	N/A

FCF Yield	2.51%
FCF Yield Avg TTM	2.37%
FCF Yield Avg 3Y	2.41%
Current VS TTM Avg	+5.76%
Current VS 3Y Avg	+4.12%
Current VS 5Y Avg	+4.12%

Earnings Yield	2.38%
Earnings Yield Avg TTM	2.47%
Earnings Yield Avg 3Y	2.01%
Current VS TTM Avg	-3.65%
Current VS 3Y Avg	+18.25%
Current VS 5Y Avg	+18.25%

EBITDA Yield	N/A
EBITDA Yield Avg TTM	N/A
EBITDA Yield Avg 3Y	N/A
Current VS TTM Avg	N/A
Current VS 3Y Avg	N/A
Current VS 5Y Avg	N/A

OCF Yield	N/A
OCF Yield Avg TTM	N/A
OCF Yield Avg 3Y	N/A
Current VS TTM Avg	N/A
Current VS 3Y Avg	N/A
Current VS 5Y Avg	N/A

Ev/Ebit Ratio	49.75
Ev/Ebit Ratio Avg TTM	47.33
Ev/Ebit Ratio Avg 3Y	47.33
Current VS TTM Avg	+5.12%
Current VS 3Y Avg	+5.11%
Current VS 5Y Avg	+5.11%

Ev/Ebitda Ratio	48.18
Ev/Ebitda Ratio Avg TTM	45.58
Ev/Ebitda Ratio Avg 3Y	44.91
Current VS TTM Avg	+5.70%
Current VS 3Y Avg	+7.27%
Current VS 5Y Avg	+7.27%

Ev/Assets Ratio	6.56
Ev/Assets Ratio Avg TTM	6.01
Ev/Assets Ratio Avg 3Y	5.09
Current VS TTM Avg	+9.17%
Current VS 3Y Avg	+28.92%
Current VS 5Y Avg	+53.19%

Ev/Sales Ratio	22.35
Ev/Sales Ratio Avg TTM	20.17
Ev/Sales Ratio Avg 3Y	24.00
Current VS TTM Avg	+10.81%
Current VS 3Y Avg	-6.88%
Current VS 5Y Avg	-6.88%

Current Ratio	8.32
Current Ratio Avg TTM	9.51
Current Ratio Avg 3Y	9.46
Current VS TTM Avg	-12.55%
Current VS 3Y Avg	-12.08%
Current VS 5Y Avg	-32.38%

Quick Ratio	7.96
Quick Ratio Avg TTM	9.13
Quick Ratio Avg 3Y	9.14
Current VS TTM Avg	-12.79%
Current VS 3Y Avg	-12.95%
Current VS 5Y Avg	-34.38%

ROIC	14.41%
ROIC Avg 3Y	1.60%
ROIC Avg 5Y	(5.61%)
Current VS 3Y Avg	+800.82%
Current VS 5Y Avg	+356.98%
Current VS 10Y Avg	+213.23%

ROA	16.09%
ROA Avg TTM	4.25%
ROA Avg 3Y	3.14%
Current VS TTM Avg	+278.16%
Current VS 3Y Avg	+412.39%
Current VS 5Y Avg	+11623.73%

ROE	17.77%
ROE Avg TTM	16.75%
ROE Avg 3Y	10.74%
Current VS TTM Avg	+6.07%
Current VS 3Y Avg	+65.39%
Current VS 5Y Avg	+861.80%

Net Profit Margin	54.82%
Net Profit Margin Avg TTM	52.61%
Net Profit Margin Avg 3Y	35.89%
Current VS TTM Avg	+4.20%
Current VS 3Y Avg	+52.72%
Current VS 5Y Avg	+154.54%

Gross Profit Margin	93.34%
Gross Pft Margin Avg TTM	93.14%
Gross Pft Margin Avg 3Y	93.31%
Current VS TTM Avg	+0.21%
Current VS 3Y Avg	+0.03%
Current VS 5Y Avg	+75.05%

Tax Rate	17.12%
Tax Rate Avg 3Y	8.93%
Tax Rate Avg 5Y	8.93%
Current VS 3Y Avg	+91.75%
Current VS 5Y Avg	+91.75%
Current VS 10Y Avg	+91.75%