What is the P/E ratio for Denali Therapeutics Inc. (DNLI)?

The P/E ratio for DNLI stock is N/A.

What is the TTM average P/E ratio for Denali Therapeutics Inc. (DNLI)?

The TTM average P/E ratio for DNLI stock is 239.54.

Denali Therapeutics (DNLI) PE Ratio: History & Chart

Basis: FMP quote price / unrounded diluted EPS from four consecutive issuer fiscal quarters. Source: stored company filings and market data; unavailable inputs remain N/A.

The P/E ratio is N/A as of 2026-10-06T17:21:24.485Z.

Stored calculation inputs

Calculation as of: 2026-10-06T17:21:24.485Z.

Quote observation: 2026-10-06T17:20:14.000Z. Amounts in USD. The price header may show a later quote.

Quote price: 19.41
Unrounded diluted TTM EPS · period ending 2026-06-30: -2.84

FMP input reference: a052b5393ab77f1e77aa428053085e4d751b04d668ff3bc446a118ef207c6094

Forward PE Ratio|PEG Ratio|P/B Ratio|EPS|All Metrics

DNLI PE Ratio Metrics

PE RATIO

N/A

PE RATIO AVG TTM

239.54

PE RATIO AVG 3Y

N/A

PE RATIO AVG 5Y

N/A

PE RATIO AVG 10Y

N/A

PE RATIO AVG 15Y

N/A

PE RATIO AVG 20Y

N/A

CURRENT VS TTM AVG

N/A

CURRENT VS 3Y AVG

N/A

CURRENT VS 5Y AVG

N/A

CURRENT VS 10Y AVG

N/A

CURRENT VS 15Y AVG

N/A

CURRENT VS 20Y AVG

N/A

DNLI Competitors' PE Ratio

DNLI

Denali Therapeutics Inc.

Current

Market Cap

$3.08B

PE Ratio

N/A

TTM Avg

239.54

3Y Avg

N/A

5Y Avg

N/A

AMLX

Amylyx Pharmaceuticals, Inc.

vs DNLI

Market Cap

$3.07B

PE Ratio

N/A

TTM Avg

7.81

3Y Avg

7.81

5Y Avg

7.81

ARQT

Arcutis Biotherapeutics, Inc.

vs DNLI

Market Cap

$3.01B

PE Ratio

115.49

TTM Avg

121.55

3Y Avg

121.55

5Y Avg

121.55

ELVN

Enliven Therapeutics, Inc.

vs DNLI

Market Cap

$2.99B

PE Ratio

N/A

TTM Avg

N/A

3Y Avg

N/A

5Y Avg

N/A

TARS

Tarsus Pharmaceuticals, Inc.

vs DNLI

Market Cap

$3.19B

PE Ratio

N/A

TTM Avg

N/A

3Y Avg

N/A

5Y Avg

N/A

PBLS

Parabilis Medicines, Inc.

vs DNLI

Market Cap

$3.30B

PE Ratio

N/A

TTM Avg

N/A

3Y Avg

N/A

5Y Avg

N/A

DYN

Dyne Therapeutics, Inc.

vs DNLI

Market Cap

$2.82B

PE Ratio

N/A

TTM Avg

N/A

3Y Avg

N/A

5Y Avg

N/A

TMDX

TransMedics Group, Inc.

vs DNLI

Market Cap

$2.81B

PE Ratio

21.04

TTM Avg

33.77

3Y Avg

471.31

5Y Avg

471.31

ATRC

AtriCure, Inc.

vs DNLI

Market Cap

$2.79B

PE Ratio

258.29

TTM Avg

234.61

3Y Avg

234.61

5Y Avg

81.83

CDNA

CareDx, Inc

vs DNLI

Market Cap

$3.37B

PE Ratio

31.49

TTM Avg

18.61

3Y Avg

17.43

5Y Avg

17.43

NAME	MARKET CAP	PE RATIO	TTM	3Y	5Y
Denali Therapeutics Inc. (DNLI)	$3.08B	N/A	239.54	N/A	N/A
Amylyx Pharmaceuticals, Inc. (AMLX)vs ›	$3.07B	N/A	7.81	7.81	7.81
Arcutis Biotherapeutics, Inc. (ARQT)vs ›	$3.01B	115.49	121.55	121.55	121.55
Enliven Therapeutics, Inc. (ELVN)vs ›	$2.99B	N/A	N/A	N/A	N/A
Tarsus Pharmaceuticals, Inc. (TARS)vs ›	$3.19B	N/A	N/A	N/A	N/A
Parabilis Medicines, Inc. (PBLS)vs ›	$3.30B	N/A	N/A	N/A	N/A
Dyne Therapeutics, Inc. (DYN)vs ›	$2.82B	N/A	N/A	N/A	N/A
TransMedics Group, Inc. (TMDX)vs ›	$2.81B	21.04	33.77	471.31	471.31
AtriCure, Inc. (ATRC)vs ›	$2.79B	258.29	234.61	234.61	81.83
CareDx, Inc (CDNA)vs ›	$3.37B	31.49	18.61	17.43	17.43

P/E Comparison

Trailing P/E

N/A

Forward P/E

N/A

Forward P/E Calculation

View All Analyst Estimates

Forward P/E is calculated using analyst consensus EPS estimates for the current or next fiscal year.

Calculation:

Current Price

$19.41

÷

Forward EPS (Est.)

$-2.29

=

Forward P/E

N/A

Source: FMP Analyst Consensus Estimates. Forward EPS represents the average analyst estimate for the nearest fiscal year.

PE Ratio Formula & Definition

PE Ratio = Share Price / Diluted EPS (TTM)

The price-to-earnings ratio measures how much investors pay for each dollar of trailing earnings. A lower PE can indicate a cheaper valuation; a higher PE implies higher growth expectations.

Expanded definitions: Investopedia, Wikipedia, Corporate Finance Institute

PE Ratio FAQ

What is the P/E ratio for Denali Therapeutics Inc. (DNLI)?: The P/E ratio for DNLI stock is N/A.
What is the TTM average P/E ratio for Denali Therapeutics Inc. (DNLI)?: The TTM average P/E ratio for DNLI stock is 239.54.

DNLI PE Ratio History

DATE	PE RATIO
2022-02-28	217.07
2022-02-25	220.20
2022-02-24	219.47
2022-02-23	208.40
2022-02-22	219.00
2022-02-18	217.20
2022-02-17	222.93
2022-02-16	235.53
2022-02-15	237.60
2022-02-14	232.53
2022-02-11	232.33
2022-02-10	241.80
2022-02-09	255.67
2022-02-08	240.67
2022-02-07	239.47
2022-02-04	225.53
2022-02-03	224.93
2022-02-02	226.73
2022-02-01	235.67
2022-01-31	228.13
2022-01-28	215.80
2022-01-27	209.67
2022-01-26	221.67
2022-01-25	224.87
2022-01-24	231.73
2022-01-21	215.73
2022-01-20	218.93
2022-01-19	221.13
2022-01-18	209.47
2022-01-14	232.27
2022-01-13	225.73
2022-01-12	257.00
2022-01-11	278.27
2022-01-10	269.40
2022-01-07	277.07
2022-01-06	293.07
2022-01-05	297.00
2022-01-04	304.53
2022-01-03	315.13
2021-12-31	297.33
2021-12-30	300.33
2021-12-29	293.73
2021-12-28	295.33
2021-12-27	299.27
2021-12-23	316.33
2021-12-22	311.87
2021-12-21	306.13
2021-12-20	297.93
2021-12-17	315.13
2021-12-16	298.80
2021-12-15	303.40
2021-12-14	301.40
2021-12-13	304.53
2021-12-10	288.73
2021-12-09	296.67
2021-12-08	307.73
2021-12-07	295.80
2021-12-06	286.87
2021-12-03	283.93
2021-12-02	296.73
2021-12-01	296.13
2021-11-30	308.40
2021-11-29	295.67
2021-11-26	300.13
2021-11-24	317.60
2021-11-23	309.40
2021-11-22	301.73
2021-11-19	314.07
2021-11-18	313.73
2021-11-17	328.20
2021-11-16	336.20
2021-11-15	334.13
2021-11-12	338.60
2021-11-11	340.53
2021-11-10	347.73
2021-11-09	353.13
2021-11-08	360.67
2021-11-05	366.80
2021-11-04	175.60
2021-11-03	177.23
2021-11-02	170.60
2021-11-01	166.87
2021-10-29	161.17
2021-10-28	163.07
2021-10-27	156.27
2021-10-26	158.87
2021-10-25	158.57
2021-10-22	159.33
2021-10-21	153.90
2021-10-20	149.17
2021-10-19	147.60
2021-10-18	150.67
2021-10-15	151.87
2021-10-14	151.47
2021-10-13	149.33
2021-10-12	150.97
2021-10-11	157.07
2021-10-08	169.70
2021-10-07	173.73
2021-10-06	166.60
2021-10-05	167.60
2021-10-04	169.23
2021-10-01	169.93
2021-09-30	168.17
2021-09-29	164.73
2021-09-28	168.47
2021-09-27	172.77
2021-09-24	170.00
2021-09-23	176.33
2021-09-22	173.27
2021-09-21	177.40
2021-09-20	166.20
2021-09-17	176.10
2021-09-16	176.77
2021-09-15	175.43
2021-09-14	172.77
2021-09-13	174.53
2021-09-10	172.10
2021-09-09	176.63
2021-09-08	177.37
2021-09-07	179.93
2021-09-03	181.77
2021-09-02	186.57
2021-09-01	184.00
2021-08-31	177.33
2021-08-30	176.37
2021-08-27	177.17
2021-08-26	166.67
2021-08-25	174.03
2021-08-24	174.60
2021-08-23	172.37
2021-08-20	163.13
2021-08-19	161.60
2021-08-18	169.67
2021-08-17	173.03
2021-08-16	172.67
2021-08-13	175.77
2021-08-12	176.43
2021-08-11	176.50
2021-08-10	178.77
2021-08-09	178.30
2021-08-06	173.50
2021-08-05	176.43
2021-08-04	221.22
2021-08-03	222.30
2021-08-02	219.48
2021-07-30	221.87
2021-07-29	221.70
2021-07-28	224.00
2021-07-27	213.04
2021-07-26	235.39
2021-07-23	277.83
2021-07-22	280.61
2021-07-21	284.39
2021-07-20	281.74
2021-07-19	281.17
2021-07-16	280.22
2021-07-15	279.22
2021-07-14	278.09
2021-07-13	291.96
2021-07-12	302.30
2021-07-09	314.09
2021-07-08	322.17
2021-07-07	331.35
2021-07-06	338.39
2021-07-02	334.78
2021-07-01	340.13
2021-06-30	341.04
2021-06-29	334.26
2021-06-28	326.30
2021-06-25	324.70
2021-06-24	319.30
2021-06-23	308.83
2021-06-22	300.61
2021-06-21	316.22
2021-06-18	320.57
2021-06-17	325.26
2021-06-16	320.04
2021-06-15	319.91
2021-06-14	326.35
2021-06-11	326.09
2021-06-10	322.65
2021-06-09	315.22
2021-06-08	316.26
2021-06-07	312.35
2021-06-04	281.04
2021-06-03	280.48
2021-06-02	277.22
2021-06-01	267.78
2021-05-28	276.48
2021-05-27	286.83
2021-05-26	282.13
2021-05-25	281.04
2021-05-24	267.57
2021-05-21	256.09
2021-05-20	256.52
2021-05-19	241.22
2021-05-18	241.35
2021-05-17	233.22
2021-05-14	234.35
2021-05-13	224.78
2021-05-12	222.48
2021-05-11	236.91
2021-05-10	224.22
2021-05-07	236.09
2021-05-06	234.65
2021-05-05	205.54
2021-05-04	213.92
2021-05-03	224.27
2021-04-30	232.46
2021-04-29	235.85
2021-04-28	243.23
2021-04-27	236.04
2021-04-26	231.50
2021-04-23	218.42
2021-04-22	211.77
2021-04-21	213.38
2021-04-20	201.27
2021-04-19	204.19
2021-04-16	207.73
2021-04-15	215.54
2021-04-14	212.62
2021-04-13	207.92
2021-04-12	193.46
2021-04-09	201.00
2021-04-08	203.81
2021-04-07	201.65
2021-04-06	210.73
2021-04-05	213.08
2021-04-01	215.12
2021-03-31	219.62
2021-03-30	208.50
2021-03-29	206.92
2021-03-26	212.50
2021-03-25	213.85
2021-03-24	209.96
2021-03-23	223.85
2021-03-22	236.58
2021-03-19	238.50
2021-03-18	228.85
2021-03-17	247.54
2021-03-16	240.19
2021-03-15	238.50
2021-03-12	248.81
2021-03-11	252.77
2021-03-10	225.15
2021-03-09	223.96
2021-03-08	217.81
2021-03-05	234.77
2021-03-04	225.77
2021-03-03	236.00
2021-03-02	242.00
2021-03-01	248.69

See the Lowest P/E Ratio Stocks ranking →

PE Ratio: N/A

DNLI PE Ratio Chart

DNLI Average PE Ratio Chart

DNLI PE Ratio Metrics

DNLI Competitors' PE Ratio

P/E Comparison

Forward P/E Calculation

PE Ratio Formula & Definition

PE Ratio FAQ

DNLI PE Ratio History

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