AtriCure, Inc. (ATRC) vs Denali Therapeutics Inc. (DNLI)
A side-by-side comparison of AtriCure, Inc. and Denali Therapeutics Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
ATRC
AtriCure, Inc.
$53.68HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT
DNLI
Denali Therapeutics Inc.
$19.28HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT
Total return — ATRC vs DNLI
growth of $100 · dividends reinvested · last 9yATRC +213.9% (+13.6%/yr)DNLI -7.2% (-0.8%/yr)ATRC compounded faster over this window
ATRC DNLI
ATRC vs DNLI: by the numbers
- •DNLI is the larger company ($3.06B vs $2.73B market cap).
- •ATRC is profitable (1.85% net margin) while DNLI runs a net loss (-14191.20%).
- •DNLI grew revenue faster over the past five years (20.68% vs 18.57% CAGR).
Metrics side by side
Valuation
| Metric | ATRC | DNLI |
|---|---|---|
| P/E ratio | 252.97 | N/A |
| P/S ratio | 4.79 | 849.04 |
| P/B ratio | 5.29 | 3.66 |
| EV / EBITDA | 75.80 | N/A |
| FCF yield | 1.88% | N/A |
Profitability
| Metric | ATRC | DNLI |
|---|---|---|
| Gross margin | 76.16% | 0.00% |
| Operating margin | 2.44% | 0.00% |
| Net margin | 1.85% | -14191.20% |
| ROE | 2.04% | -61.24% |
| ROIC | 2.04% | -50.82% |
Growth (annualized)
| Metric | ATRC | DNLI |
|---|---|---|
| Revenue CAGR (5Y) | 18.57% | 20.68% |
| Total return CAGR (5Y) | -4.06% | -16.91% |
Frequently asked
- Which has grown faster, ATRC or DNLI?
- Over the past five years, DNLI grew revenue faster — ATRC at a 18.57% CAGR versus DNLI at 20.68%.
- Is ATRC or DNLI more profitable?
- ATRC runs the higher net margin — ATRC at 1.85% versus DNLI at -14191.20%.
- How have ATRC and DNLI total returns compared?
- Over the past 5 years, ATRC delivered -4.06% and DNLI delivered -16.91% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
AtriCure P/E ratioAtriCure ROEDenali Therapeutics ROEAtriCure operating marginDenali Therapeutics operating marginAtriCure revenue growthDenali Therapeutics revenue growthAtriCure free cash flowDenali Therapeutics free cash flow
AtriCure & Denali Therapeutics appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.