Denali Therapeutics Inc. (DNLI) vs Tarsus Pharmaceuticals, Inc. (TARS)
A side-by-side comparison of Denali Therapeutics Inc. and Tarsus Pharmaceuticals, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
DNLI
Denali Therapeutics Inc.
$19.50HealthcareDelayed quote: Oct 6, 2026, 2:05 PM EDT
TARS
Tarsus Pharmaceuticals, Inc.
$74.20HealthcareDelayed quote: Oct 6, 2026, 2:05 PM EDT
Total return — DNLI vs TARS
growth of $100 · dividends reinvested · last 6yDNLI -53.9% (-12.1%/yr)TARS +261.8% (+23.9%/yr)TARS compounded faster over this window
Log scale — wide-divergence pair
DNLI TARS
DNLI vs TARS: by the numbers
- •TARS is the larger company ($3.19B vs $3.10B market cap).
- •Both run net losses; TARS's is the smaller (-7.67% vs -14191.20% net margin).
- •TARS grew revenue faster over the past five years (61.36% vs 20.68% CAGR).
Metrics side by side
Valuation
| Metric | DNLI | TARS |
|---|---|---|
| P/S ratio | 858.93 | 5.27 |
| P/B ratio | 3.71 | 9.21 |
| FCF yield | N/A | 1.93% |
Profitability
| Metric | DNLI | TARS |
|---|---|---|
| Gross margin | 0.00% | 90.59% |
| Operating margin | 0.00% | -8.00% |
| Net margin | -14191.20% | -7.67% |
| ROE | -61.24% | -13.40% |
| ROIC | -50.82% | -11.15% |
Growth (annualized)
| Metric | DNLI | TARS |
|---|---|---|
| Revenue CAGR (5Y) | 20.68% | 61.36% |
| Total return CAGR (5Y) | -16.91% | 28.33% |
Frequently asked
- Which has grown faster, DNLI or TARS?
- Over the past five years, TARS grew revenue faster — DNLI at a 20.68% CAGR versus TARS at 61.36%.
- How have DNLI and TARS total returns compared?
- Over the past 5 years, DNLI delivered -16.91% and TARS delivered 28.33% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Denali Therapeutics ROETarsus Pharmaceuticals ROEDenali Therapeutics operating marginTarsus Pharmaceuticals operating marginDenali Therapeutics revenue growthTarsus Pharmaceuticals revenue growthDenali Therapeutics free cash flowTarsus Pharmaceuticals free cash flow
Denali Therapeutics & Tarsus Pharmaceuticals appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.