Which has grown faster, DNLI or TMDX?

Over the past five years, TMDX grew revenue faster — DNLI at a 20.68% CAGR versus TMDX at 86.12%.

Is DNLI or TMDX more profitable?

TMDX runs the higher net margin — DNLI at -14191.20% versus TMDX at 22.69%.

How have DNLI and TMDX total returns compared?

Over the past 5 years, DNLI delivered -16.91% and TMDX delivered 21.77% annualized total return. Past performance doesn't predict future results.

Denali Therapeutics Inc. (DNLI) vs TransMedics Group, Inc. (TMDX)

A side-by-side comparison of Denali Therapeutics Inc. and TransMedics Group, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

DNLI

Denali Therapeutics Inc.

$3.16B

$19.91HealthcareDelayed quote: Oct 5, 2026, 4:00 PM EDT

TMDX

TransMedics Group, Inc.

$2.87B

$82.99HealthcareDelayed quote: Oct 5, 2026, 4:00 PM EDT

Total return — DNLI vs TMDX

growth of $100 · dividends reinvested · last 7y

DNLI -16.4% (-2.5%/yr)TMDX +271.2% (+20.6%/yr)TMDX compounded faster over this window

DNLI TMDX

DNLI vs TMDX: by the numbers

•DNLI is the larger company ($3.16B vs $2.87B market cap).
•TMDX is profitable (22.69% net margin) while DNLI runs a net loss (-14191.20%).
•TMDX grew revenue faster over the past five years (86.12% vs 20.68% CAGR).

Metrics side by side

Valuation

Metric	DNLI	TMDX
P/E ratio	N/A	21.50
Forward P/E	N/A	56.57
P/S ratio	876.78	4.29
P/B ratio	3.78	5.54
EV / EBITDA	N/A	27.65
FCF yield	N/A	2.76%

Profitability

Metric	DNLI	TMDX
Gross margin	0.00%	58.69%
Operating margin	0.00%	12.21%
Net margin	-14191.20%	22.69%
ROE	-61.24%	29.28%
ROIC	-50.82%	5.87%

Growth (annualized)

Metric	DNLI	TMDX
Revenue CAGR (5Y)	20.68%	86.12%
Total return CAGR (5Y)	-16.91%	21.77%

Frequently asked

Which has grown faster, DNLI or TMDX?: Over the past five years, TMDX grew revenue faster — DNLI at a 20.68% CAGR versus TMDX at 86.12%.
Is DNLI or TMDX more profitable?: TMDX runs the higher net margin — DNLI at -14191.20% versus TMDX at 22.69%.
How have DNLI and TMDX total returns compared?: Over the past 5 years, DNLI delivered -16.91% and TMDX delivered 21.77% annualized total return. Past performance doesn't predict future results.

Go deeper

Full DNLI analysis Full TMDX analysis Interactive comparison tool

Dig into the metrics

TransMedics P/E ratio Denali Therapeutics ROE TransMedics ROE Denali Therapeutics operating margin TransMedics operating margin Denali Therapeutics revenue growth TransMedics revenue growth Denali Therapeutics free cash flow TransMedics free cash flow

Denali Therapeutics & TransMedics appear in these rankings

Fastest Revenue Growth Stocks Highest ROE Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.