Charles River Laboratories International (CRL) Net Profit Margin: History & Chart

Charles River Laboratories International, Inc.(CRL)

Medical - Diagnostics & Research · Wilmington, MA

$280.76+0.00 (+0.00%)

Delayed quote: Sep 8, 2026, 4:00 PM EDT

About Charles River Laboratories International, Inc.

Charles River Laboratories International, Inc. operates as a contract research organization (CRO), providing essential preclinical services to the pharmaceutical and biotechnology industries. Its core business revolves around assisting clients with drug discovery, non-clinical development, and thorough safety testing, with its services extending globally across the United States, Europe, Canada, and the Asia Pacific region. The company organizes its diverse offerings into three principal segments: Research Models and Services (RMS), Discovery and Safety Assessment (DSA), and Manufacturing Solutions. 1. Research Models and Services (RMS): This division is a key supplier of high-quality rodent research models, including specially bred strains of rats and mice for experimental purposes. It also offers a comprehensive array of support services to help clients effectively utilize these models in their research and for the screening of potential non-clinical drug candidates. These include providing genetically engineered models, insourcing solutions for facility management, and diagnostic services for research animals. 2. Discovery and Safety Assessment (DSA): The DSA segment plays a crucial role in advancing early-stage drug pipelines. It delivers early-phase and in vivo discovery services focused on identifying and validating new therapeutic targets, chemical compounds, and antibodies. The ultimate goal is to prepare promising non-clinical drug and therapeutic candidates for subsequent safety evaluations. Additionally, this segment provides an extensive range of safety assessment services, such as toxicology, pathology, safety pharmacology, bioanalysis, drug metabolism studies, and pharmacokinetics. 3. Manufacturing Solutions: This segment addresses critical quality control requirements by offering in vitro methods for both routine and rapid testing of the quality of sterile and non-sterile pharmaceuticals, as well as consumer products. It also serves as a vital provider of specialized biologics testing, which is often outsourced by pharmaceutical and biotechnology companies. Furthermore, the segment supplies avian vaccine services, including specific-pathogen-free (SPF) fertile chicken eggs, SPF chickens, and diagnostic products, all essential for vaccine production. Beyond these specialized segments, Charles River also manages contract vivarium operations, providing crucial animal housing and care facilities for its biopharmaceutical clients. The company was founded in 1947 and is headquartered in Wilmington, Massachusetts.

Wilmington, MA

19,000 employees

www.criver.com

Healthcare / Medical - Diagnostics & Research

Sector: Healthcare
Industry: Medical - Diagnostics & Research
CEO: Birgit Girshick

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CRL Net Profit Margin Metrics

NET PROFIT MARGIN

-5.96%

NET PROFIT MARGIN AVG TTM

-3.79%

NET PROFIT MARGIN AVG 3Y

6.34%

NET PROFIT MARGIN AVG 5Y

8.60%

NET PROFIT MARGIN AVG 10Y

9.58%

NET PROFIT MARGIN AVG 15Y

9.35%

NET PROFIT MARGIN AVG 20Y

9.82%

CURRENT VS TTM AVG

-57.10%

CURRENT VS 3Y AVG

-193.94%

CURRENT VS 5Y AVG

-169.32%

CURRENT VS 10Y AVG

-162.23%

CURRENT VS 15Y AVG

-163.73%

CURRENT VS 20Y AVG

-160.69%

SECTOR MEDIAN · HEALTHCARE

8.98%

median of 90 covered companies

CURRENT VS SECTOR MEDIAN

-166.37%

vs the sector median at left

NAME	MARKET CAP	NET PROFIT MARGIN	TTM	3Y	5Y
Charles River Laboratories International, Inc. (CRL)	$13.52B	-5.96%	-3.79%	6.34%	8.60%
The Cooper Companies, Inc. (COO)vs ›	$13.20B	5.57%	9.62%	9.77%	24.94%
Revvity, Inc. (RVTY)vs ›	$14.18B	8.16%	9.60%	8.02%	12.66%
Baxter International Inc. (BAX)vs ›	$12.85B	-9.27%	-7.30%	-3.29%	1.14%
Penumbra, Inc. (PEN)vs ›	$12.58B	10.67%	6.92%	5.54%	3.35%
Exelixis, Inc. (EXEL)vs ›	$14.50B	35.33%	28.88%	23.04%	19.31%
Encompass Health Corporation (EHC)vs ›	$11.95B	10.01%	9.01%	7.89%	8.30%
DaVita Inc. (DVA)vs ›	$11.56B	6.05%	6.39%	5.83%	6.41%
Solventum Corporation (SOLV)vs ›	$15.60B	17.26%	12.25%	14.36%	15.15%
Bio-Techne Corporation (TECH)vs ›	$11.32B	14.97%	10.50%	15.15%	16.71%

NAME

MARKET CAP

NET PROFIT MARGIN

TTM

Charles River Laboratories International, Inc. (CRL)

$13.52B

-5.96%

-3.79%

6.34%

8.60%

The Cooper Companies, Inc. (COO)vs ›

$13.20B

5.57%

9.62%

9.77%

24.94%

Revvity, Inc. (RVTY)vs ›

$14.18B

8.16%

9.60%

8.02%

12.66%

Baxter International Inc. (BAX)vs ›

$12.85B

-9.27%

-7.30%

-3.29%

1.14%

Penumbra, Inc. (PEN)vs ›

$12.58B

10.67%

6.92%

5.54%

3.35%

Exelixis, Inc. (EXEL)vs ›

$14.50B

35.33%

28.88%

23.04%

19.31%

Encompass Health Corporation (EHC)vs ›

$11.95B

10.01%

9.01%

7.89%

8.30%

DaVita Inc. (DVA)vs ›

$11.56B

6.05%

6.39%

5.83%

6.41%

Solventum Corporation (SOLV)vs ›

$15.60B

17.26%

12.25%

14.36%

15.15%

Bio-Techne Corporation (TECH)vs ›

$11.32B

14.97%

10.50%

15.15%

16.71%

Net Profit Margin FAQ

What is the net profit margin for Charles River Laboratories International, Inc. (CRL)?

The net profit margin for CRL stock is -5.96%.

Is Charles River Laboratories International, Inc.'s net profit margin high or low?

The net profit margin of -5.96% is 169% below its 5-year average of 8.60%, around the middle of its 5-year range (-27.82%–18.46%).

What is the TTM average net profit margin for Charles River Laboratories International, Inc. (CRL)?

The TTM average net profit margin for CRL stock is -3.79%.

What is the 3Y average net profit margin for Charles River Laboratories International, Inc. (CRL)?

The 3Y average net profit margin for CRL stock is 6.34%.

What is the 5Y average net profit margin for Charles River Laboratories International, Inc. (CRL)?

The 5Y average net profit margin for CRL stock is 8.60%.

What is the 10Y average net profit margin for Charles River Laboratories International, Inc. (CRL)?

The 10Y average net profit margin for CRL stock is 9.58%.

What is the 15Y average net profit margin for Charles River Laboratories International, Inc. (CRL)?

The 15Y average net profit margin for CRL stock is 9.35%.

What is the 20Y average net profit margin for Charles River Laboratories International, Inc. (CRL)?

The 20Y average net profit margin for CRL stock is 9.82%.

DATE	NET PROFIT MARGIN
2026-06-27	-0.15%
2026-03-28	-1.49%
2025-12-27	-27.82%
2025-09-27	5.42%
2025-06-28	5.07%
2025-03-29	2.59%
2024-12-31	-21.52%
2024-09-28	6.80%
2024-06-29	8.77%
2024-03-30	6.66%
2023-12-31	18.46%
2023-09-30	8.51%
2023-07-01	9.15%
2023-04-01	10.02%
2022-12-31	17.04%
2022-09-24	9.75%
2022-06-25	11.23%
2022-03-26	10.18%
2021-12-31	15.20%
2021-09-25	11.54%
2021-06-26	9.67%
2021-03-27	7.46%
2020-12-31	18.10%
2020-09-26	13.84%
2020-06-27	9.88%
2020-03-28	7.18%
2019-12-31	11.63%
2019-09-28	10.90%
2019-06-29	6.65%
2019-03-30	9.12%
2018-12-31	9.92%
2018-09-29	10.31%
2018-06-30	9.18%
2018-03-31	10.65%
2017-12-31	-6.24%
2017-09-30	11.30%
2017-07-01	11.50%
2017-04-01	10.49%
2016-12-31	9.57%
2016-09-24	8.86%
2016-06-25	8.11%
2016-03-26	10.47%
2015-12-31	9.01%
2015-09-26	10.70%
2015-06-27	14.29%
2015-03-28	9.84%
2014-12-31	8.24%
2014-09-27	9.78%
2014-06-28	10.34%
2014-03-29	10.77%
2013-12-31	6.60%
2013-09-28	10.57%
2013-06-29	9.31%
2013-03-30	8.78%
2012-12-31	6.57%
2012-09-29	7.88%
2012-06-30	10.70%
2012-03-31	9.25%
2011-12-31	9.32%
2011-09-24	6.77%
2011-06-25	11.21%
2011-03-26	10.96%
2010-12-31	-128.25%
2010-09-25	-9.03%
2010-06-26	4.95%
2010-03-27	5.85%
2009-12-31	5.95%
2009-09-26	12.54%
2009-06-27	11.08%
2009-03-28	8.43%
2008-12-31	-212.52%
2008-09-27	13.29%
2008-06-28	13.93%
2008-03-29	13.07%
2007-12-31	11.61%
2007-09-29	13.62%
2007-06-30	12.35%
2007-03-31	12.62%
2006-12-31	12.95%
2006-09-30	-6.27%
2006-07-01	9.61%
2006-04-01	-35.28%
2005-12-31	17.32%
2005-09-24	11.71%
2005-06-25	11.24%
2005-03-26	10.10%
2004-12-31	8.43%
2004-09-25	14.67%
2004-06-26	14.60%
2004-03-27	10.19%
2003-12-31	13.23%
2003-09-27	12.96%
2003-06-28	13.32%
2003-03-29	12.72%
2002-12-31	12.25%
2002-09-28	13.11%

DATE

NET PROFIT MARGIN

2026-06-27

-0.15%

2026-03-28

-1.49%

2025-12-27

-27.82%

2025-09-27

5.42%

2025-06-28

5.07%

2025-03-29

2.59%

2024-12-31

-21.52%

2024-09-28

6.80%

2024-06-29

8.77%

2024-03-30

6.66%

2023-12-31

18.46%

2023-09-30

8.51%

2023-07-01

9.15%

2023-04-01

10.02%

2022-12-31

17.04%

2022-09-24

9.75%

2022-06-25

11.23%

2022-03-26

10.18%

2021-12-31

15.20%

2021-09-25

11.54%

2021-06-26

9.67%

2021-03-27

7.46%

2020-12-31

18.10%

2020-09-26

13.84%

2020-06-27

9.88%

2020-03-28

7.18%

2019-12-31

11.63%

2019-09-28

10.90%

2019-06-29

6.65%

2019-03-30

9.12%

2018-12-31

9.92%

2018-09-29

10.31%

2018-06-30

9.18%

2018-03-31

10.65%

2017-12-31

-6.24%

2017-09-30

11.30%

2017-07-01

11.50%

2017-04-01

10.49%

2016-12-31

9.57%

2016-09-24

8.86%

2016-06-25

8.11%

2016-03-26

10.47%

2015-12-31

9.01%

2015-09-26

10.70%

2015-06-27

14.29%

2015-03-28

9.84%

2014-12-31

8.24%

2014-09-27

9.78%

2014-06-28

10.34%

2014-03-29

10.77%

2013-12-31

6.60%

2013-09-28

10.57%

2013-06-29

9.31%

2013-03-30

8.78%

2012-12-31

6.57%

2012-09-29

7.88%

2012-06-30

10.70%

2012-03-31

9.25%

2011-12-31

9.32%

2011-09-24

6.77%

2011-06-25

11.21%

2011-03-26

10.96%

2010-12-31

-128.25%

2010-09-25

-9.03%

2010-06-26

4.95%

2010-03-27

5.85%

2009-12-31

5.95%

2009-09-26

12.54%

2009-06-27

11.08%

2009-03-28

8.43%

2008-12-31

-212.52%

2008-09-27

13.29%

2008-06-28

13.93%

2008-03-29

13.07%

2007-12-31

11.61%

2007-09-29

13.62%

2007-06-30

12.35%

2007-03-31

12.62%

2006-12-31

12.95%

2006-09-30

-6.27%

2006-07-01

9.61%

2006-04-01

-35.28%

2005-12-31

17.32%

2005-09-24

11.71%

2005-06-25

11.24%

2005-03-26

10.10%

2004-12-31

8.43%

2004-09-25

14.67%

2004-06-26

14.60%

2004-03-27

10.19%

2003-12-31

13.23%

2003-09-27

12.96%

2003-06-28

13.32%

2003-03-29

12.72%

2002-12-31

12.25%

2002-09-28

13.11%

Net Profit Margin: -5.96%

CRL Profit Margin

CRL Average Net Profit Margin Chart

CRL Current vs Average Net Profit Margin Chart

CRL Net Profit Margin Metrics

CRL Competitors' Net Profit Margin

Margin Comparison

Net Profit Margin Formula & Definition

Net Profit Margin FAQ

CRL Net Profit Margin History

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