Charles River Laboratories International (CRL) Operating Margin: History & Chart

Charles River Laboratories International, Inc.(CRL)

Medical - Diagnostics & Research · Wilmington, MA

$272.88-0.23 (-0.08%)

Delayed quote: Sep 15, 2026, 4:00 PM EDT

About Charles River Laboratories International, Inc.

Charles River Laboratories International, Inc. operates as a contract research organization (CRO), providing essential preclinical services to the pharmaceutical and biotechnology industries. Its core business revolves around assisting clients with drug discovery, non-clinical development, and thorough safety testing, with its services extending globally across the United States, Europe, Canada, and the Asia Pacific region. The company organizes its diverse offerings into three principal segments: Research Models and Services (RMS), Discovery and Safety Assessment (DSA), and Manufacturing Solutions. 1. Research Models and Services (RMS): This division is a key supplier of high-quality rodent research models, including specially bred strains of rats and mice for experimental purposes. It also offers a comprehensive array of support services to help clients effectively utilize these models in their research and for the screening of potential non-clinical drug candidates. These include providing genetically engineered models, insourcing solutions for facility management, and diagnostic services for research animals. 2. Discovery and Safety Assessment (DSA): The DSA segment plays a crucial role in advancing early-stage drug pipelines. It delivers early-phase and in vivo discovery services focused on identifying and validating new therapeutic targets, chemical compounds, and antibodies. The ultimate goal is to prepare promising non-clinical drug and therapeutic candidates for subsequent safety evaluations. Additionally, this segment provides an extensive range of safety assessment services, such as toxicology, pathology, safety pharmacology, bioanalysis, drug metabolism studies, and pharmacokinetics. 3. Manufacturing Solutions: This segment addresses critical quality control requirements by offering in vitro methods for both routine and rapid testing of the quality of sterile and non-sterile pharmaceuticals, as well as consumer products. It also serves as a vital provider of specialized biologics testing, which is often outsourced by pharmaceutical and biotechnology companies. Furthermore, the segment supplies avian vaccine services, including specific-pathogen-free (SPF) fertile chicken eggs, SPF chickens, and diagnostic products, all essential for vaccine production. Beyond these specialized segments, Charles River also manages contract vivarium operations, providing crucial animal housing and care facilities for its biopharmaceutical clients. The company was founded in 1947 and is headquartered in Wilmington, Massachusetts.

Wilmington, MA

19,000 employees

www.criver.com

Healthcare / Medical - Diagnostics & Research

Sector: Healthcare
Industry: Medical - Diagnostics & Research
CEO: Birgit Girshick

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CRL Operating Margin Metrics

OPERATING MARGIN

12.35%

OPERATING MARGIN AVG TTM

11.82%

OPERATING MARGIN AVG 3Y

12.85%

OPERATING MARGIN AVG 5Y

14.08%

OPERATING MARGIN AVG 10Y

14.32%

OPERATING MARGIN AVG 15Y

14.45%

OPERATING MARGIN AVG 20Y

14.84%

CURRENT VS TTM AVG

+4.50%

CURRENT VS 3Y AVG

-3.91%

CURRENT VS 5Y AVG

-12.27%

CURRENT VS 10Y AVG

-13.77%

CURRENT VS 15Y AVG

-14.54%

CURRENT VS 20Y AVG

-16.77%

SECTOR MEDIAN · HEALTHCARE

14.90%

median of 90 covered companies

CURRENT VS SECTOR MEDIAN

-17.11%

vs the sector median at left

NAME	MARKET CAP	OPERATING MARGIN	TTM	3Y	5Y
Charles River Laboratories International, Inc. (CRL)	$13.14B	12.35%	11.82%	12.85%	14.08%
Penumbra, Inc. (PEN)vs ›	$12.54B	12.45%	10.35%	7.09%	3.40%
Baxter International Inc. (BAX)vs ›	$12.26B	-2.39%	-1.31%	-6.02%	0.15%
DaVita Inc. (DVA)vs ›	$12.26B	15.06%	15.52%	13.94%	14.32%
Encompass Health Corporation (EHC)vs ›	$12.10B	18.00%	16.91%	21.06%	16.78%
Tempus AI, Inc. (TEM)vs ›	$12.06B	-19.76%	-59.77%	-59.80%	-72.77%
Exelixis, Inc. (EXEL)vs ›	$14.30B	39.88%	32.73%	24.94%	21.46%
Bio-Techne Corporation (TECH)vs ›	$11.33B	20.73%	14.55%	18.31%	20.93%
Molina Healthcare, Inc. (MOH)vs ›	$10.80B	0.66%	2.96%	3.72%	4.01%
Universal Health Services, Inc. (UHS)vs ›	$10.71B	11.36%	11.05%	9.46%	10.06%

NAME

MARKET CAP

OPERATING MARGIN

TTM

Charles River Laboratories International, Inc. (CRL)

$13.14B

12.35%

11.82%

12.85%

14.08%

Penumbra, Inc. (PEN)vs ›

$12.54B

12.45%

10.35%

7.09%

3.40%

Baxter International Inc. (BAX)vs ›

$12.26B

-2.39%

-1.31%

-6.02%

0.15%

DaVita Inc. (DVA)vs ›

$12.26B

15.06%

15.52%

13.94%

14.32%

Encompass Health Corporation (EHC)vs ›

$12.10B

18.00%

16.91%

21.06%

16.78%

Tempus AI, Inc. (TEM)vs ›

$12.06B

-19.76%

-59.77%

-59.80%

-72.77%

Exelixis, Inc. (EXEL)vs ›

$14.30B

39.88%

32.73%

24.94%

21.46%

Bio-Techne Corporation (TECH)vs ›

$11.33B

20.73%

14.55%

18.31%

20.93%

Molina Healthcare, Inc. (MOH)vs ›

$10.80B

0.66%

2.96%

3.72%

4.01%

Universal Health Services, Inc. (UHS)vs ›

$10.71B

11.36%

11.05%

9.46%

10.06%

Operating Margin FAQ

What is the operating margin for Charles River Laboratories International, Inc. (CRL)?

The operating margin for CRL stock is 12.35%.

Is Charles River Laboratories International, Inc.'s operating margin high or low?

The operating margin of 12.35% is 12% below its 5-year average of 14.08%, near the high end of its 5-year range (-16.73%–19.26%).

What is the TTM average operating margin for Charles River Laboratories International, Inc. (CRL)?

The TTM average operating margin for CRL stock is 11.82%.

What is the 3Y average operating margin for Charles River Laboratories International, Inc. (CRL)?

The 3Y average operating margin for CRL stock is 12.85%.

What is the 5Y average operating margin for Charles River Laboratories International, Inc. (CRL)?

The 5Y average operating margin for CRL stock is 14.08%.

What is the 10Y average operating margin for Charles River Laboratories International, Inc. (CRL)?

The 10Y average operating margin for CRL stock is 14.32%.

What is the 15Y average operating margin for Charles River Laboratories International, Inc. (CRL)?

The 15Y average operating margin for CRL stock is 14.45%.

What is the 20Y average operating margin for Charles River Laboratories International, Inc. (CRL)?

The 20Y average operating margin for CRL stock is 14.84%.

DATE	OPERATING MARGIN
2026-06-27	11.94%
2026-03-28	12.04%
2025-12-27	12.09%
2025-09-27	13.32%
2025-06-28	9.70%
2025-03-29	7.59%
2024-12-31	-16.73%
2024-09-28	11.63%
2024-06-29	14.78%
2024-03-30	12.45%
2023-12-31	13.12%
2023-09-30	14.76%
2023-07-01	15.56%
2023-04-01	16.31%
2022-12-31	14.89%
2022-09-24	15.26%
2022-06-25	19.26%
2022-03-26	16.28%
2021-12-31	19.09%
2021-09-25	17.39%
2021-06-26	15.04%
2021-03-27	15.00%
2020-12-31	16.30%
2020-09-26	17.86%
2020-06-27	11.25%
2020-03-28	13.33%
2019-12-31	15.74%
2019-09-28	13.89%
2019-06-29	12.13%
2019-03-30	11.54%
2018-12-31	17.04%
2018-09-29	14.41%
2018-06-30	13.11%
2018-03-31	13.73%
2017-12-31	13.11%
2017-09-30	15.95%
2017-07-01	17.41%
2017-04-01	15.64%
2016-12-31	14.80%
2016-09-24	13.81%
2016-06-25	13.38%
2016-03-26	14.50%
2015-12-31	14.77%
2015-09-26	15.86%
2015-06-27	16.41%
2015-03-28	13.42%
2014-12-31	12.37%
2014-09-27	14.10%
2014-06-28	14.96%
2014-03-29	13.26%
2013-12-31	8.51%
2013-09-28	13.98%
2013-06-29	14.74%
2013-03-30	14.68%
2012-12-31	12.52%
2012-09-29	13.52%
2012-06-30	17.31%
2012-03-31	15.29%
2011-12-31	14.31%
2011-09-24	13.36%
2011-06-25	18.49%
2011-03-26	14.78%
2010-12-31	-134.88%
2010-09-25	2.34%
2010-06-26	10.27%
2010-03-27	10.15%
2009-12-31	10.81%
2009-09-26	14.94%
2009-06-27	16.44%
2009-03-28	13.23%
2008-12-31	-208.96%
2008-09-27	19.92%
2008-06-28	19.68%
2008-03-29	18.80%
2007-12-31	16.39%
2007-09-29	20.27%
2007-06-30	18.45%
2007-03-31	18.78%
2006-12-31	16.62%
2006-09-30	19.62%
2006-07-01	17.81%
2006-04-01	-29.94%
2005-12-31	12.46%
2005-09-24	18.07%
2005-06-25	17.31%
2005-03-26	16.58%
2004-12-31	13.96%
2004-09-25	24.64%
2004-06-26	24.53%
2004-03-27	22.89%
2003-12-31	22.71%
2003-09-27	22.66%
2003-06-28	22.68%
2003-03-29	22.25%
2002-12-31	21.66%
2002-09-28	23.00%

DATE

OPERATING MARGIN

2026-06-27

11.94%

2026-03-28

12.04%

2025-12-27

12.09%

2025-09-27

13.32%

2025-06-28

9.70%

2025-03-29

7.59%

2024-12-31

-16.73%

2024-09-28

11.63%

2024-06-29

14.78%

2024-03-30

12.45%

2023-12-31

13.12%

2023-09-30

14.76%

2023-07-01

15.56%

2023-04-01

16.31%

2022-12-31

14.89%

2022-09-24

15.26%

2022-06-25

19.26%

2022-03-26

16.28%

2021-12-31

19.09%

2021-09-25

17.39%

2021-06-26

15.04%

2021-03-27

15.00%

2020-12-31

16.30%

2020-09-26

17.86%

2020-06-27

11.25%

2020-03-28

13.33%

2019-12-31

15.74%

2019-09-28

13.89%

2019-06-29

12.13%

2019-03-30

11.54%

2018-12-31

17.04%

2018-09-29

14.41%

2018-06-30

13.11%

2018-03-31

13.73%

2017-12-31

13.11%

2017-09-30

15.95%

2017-07-01

17.41%

2017-04-01

15.64%

2016-12-31

14.80%

2016-09-24

13.81%

2016-06-25

13.38%

2016-03-26

14.50%

2015-12-31

14.77%

2015-09-26

15.86%

2015-06-27

16.41%

2015-03-28

13.42%

2014-12-31

12.37%

2014-09-27

14.10%

2014-06-28

14.96%

2014-03-29

13.26%

2013-12-31

8.51%

2013-09-28

13.98%

2013-06-29

14.74%

2013-03-30

14.68%

2012-12-31

12.52%

2012-09-29

13.52%

2012-06-30

17.31%

2012-03-31

15.29%

2011-12-31

14.31%

2011-09-24

13.36%

2011-06-25

18.49%

2011-03-26

14.78%

2010-12-31

-134.88%

2010-09-25

2.34%

2010-06-26

10.27%

2010-03-27

10.15%

2009-12-31

10.81%

2009-09-26

14.94%

2009-06-27

16.44%

2009-03-28

13.23%

2008-12-31

-208.96%

2008-09-27

19.92%

2008-06-28

19.68%

2008-03-29

18.80%

2007-12-31

16.39%

2007-09-29

20.27%

2007-06-30

18.45%

2007-03-31

18.78%

2006-12-31

16.62%

2006-09-30

19.62%

2006-07-01

17.81%

2006-04-01

-29.94%

2005-12-31

12.46%

2005-09-24

18.07%

2005-06-25

17.31%

2005-03-26

16.58%

2004-12-31

13.96%

2004-09-25

24.64%

2004-06-26

24.53%

2004-03-27

22.89%

2003-12-31

22.71%

2003-09-27

22.66%

2003-06-28

22.68%

2003-03-29

22.25%

2002-12-31

21.66%

2002-09-28

23.00%

Operating Margin: 12.35%

CRL Operating Margin

CRL Average Operating Margin Chart

CRL Current vs Average Operating Margin Chart

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CRL Competitors' Operating Margin

Operating Efficiency

Operating Margin Formula & Definition

Operating Margin FAQ

CRL Operating Margin History

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