Charles River Laboratories International, Inc. (CRL) vs Tempus AI, Inc. (TEM)
A side-by-side comparison of Charles River Laboratories International, Inc. and Tempus AI, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of September 13, 2026. Differences are shown without an overall score or investment verdict.
CRL
Charles River Laboratories International, Inc.
$272.88HealthcareDelayed quote: Sep 15, 2026, 4:00 PM EDT
TEM
Tempus AI, Inc.
$68.85HealthcareDelayed quote: Sep 15, 2026, 4:00 PM EDT
Total return — CRL vs TEM
growth of $100 · dividends reinvested · last 2yCRL +29.7% (+13.9%/yr)TEM +46.6% (+21.1%/yr)TEM compounded faster over this window
CRL TEM
CRL vs TEM: by the numbers
- •CRL is the larger company ($13.14B vs $12.06B market cap).
- •Both run net losses; CRL's is the smaller (-5.96% vs -17.77% net margin).
- •TEM grew revenue faster over the past five years (38.24% vs 4.08% CAGR).
Metrics side by side
Valuation
| Metric | CRL | TEM |
|---|---|---|
| Forward P/E | 24.11 | N/A |
| P/S ratio | 3.29 | 8.42 |
| P/B ratio | 4.63 | 27.11 |
| EV / EBITDA | 20.18 | N/A |
| FCF yield | 2.82% | N/A |
Profitability
| Metric | CRL | TEM |
|---|---|---|
| Gross margin | 32.24% | 63.98% |
| Operating margin | 12.35% | -19.76% |
| Net margin | -5.96% | -17.77% |
| ROE | -8.40% | -57.18% |
| ROIC | 7.72% | -14.34% |
Growth (annualized)
| Metric | CRL | TEM |
|---|---|---|
| Revenue CAGR (5Y) | 4.08% | 38.24% |
| EPS CAGR (5Y) | -47.86% | N/A |
| FCF CAGR (5Y) | 6.43% | N/A |
| Total return CAGR (5Y) | -8.79% | N/A |
Frequently asked
- Which has grown faster, CRL or TEM?
- Over the past five years, TEM grew revenue faster — CRL at a 4.08% CAGR versus TEM at 38.24%.
Go deeper
Dig into the metrics
Charles River Laboratories International ROETempus AI ROECharles River Laboratories International operating marginTempus AI operating marginCharles River Laboratories International revenue growthTempus AI revenue growthCharles River Laboratories International free cash flowTempus AI free cash flow
Charles River Laboratories International & Tempus AI appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified September 13, 2026.