Charles River Laboratories International, Inc. (CRL) vs Tempus AI, Inc. (TEM)
CRL leads on 6 of 8 compared metrics.
A side-by-side comparison of Charles River Laboratories International, Inc. and Tempus AI, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of June 13, 2026. The ● marks the stronger figure on each row (cheaper multiple, higher margin/return).
CRL
Charles River Laboratories International, Inc.
$187.51Healthcare
TEM
Tempus AI, Inc.
$47.82Healthcare
Total return — CRL vs TEM
growth of $100 · last 2yCRL -10.0%TEM +31.1%TEM compounded faster
CRL TEM
CRL vs TEM: by the numbers
- •CRL is the larger company ($9.03B vs $8.35B market cap).
- •Both run net losses; CRL's is the smaller (-4.59% vs -22.20% net margin).
- •TEM grew revenue faster over the past five years (42.06% vs 5.77% CAGR).
Which is better, CRL or TEM?
Metric tally: CRL 6 · TEM 2It depends on what you're optimizing for:
GrowthTEM(faster 5Y revenue CAGR)
QualityCRL(higher ROIC)
Valuation
| Metric | CRL | TEM |
|---|---|---|
| Forward P/E | 15.21 | — |
| P/S ratio | 2.28● | 6.27 |
| P/B ratio | 3.12● | 20.55 |
| EV / EBITDA | 41.45 | — |
| FCF yield | 4.26% | — |
Profitability
| Metric | CRL | TEM |
|---|---|---|
| Gross margin | 31.86% | 69.55%● |
| Operating margin | 11.77%● | -18.13% |
| Net margin | -4.59%● | -22.20% |
| ROE | -6.28%● | -72.74% |
| ROIC | 8.36%● | -10.29% |
Growth (annualized)
| Metric | CRL | TEM |
|---|---|---|
| Revenue CAGR (5Y) | 5.77% | 42.06%● |
| EPS CAGR (5Y) | -40.99% | — |
| FCF CAGR (5Y) | -3.98% | — |
| Total return CAGR (5Y) | -11.83% | — |
Frequently asked
- Which is better, CRL or TEM?
- It depends on your goal. growth: TEM (faster 5Y revenue CAGR); quality: CRL (higher ROIC). Across all compared metrics, CRL leads 6 to 2.
- Which has grown faster, CRL or TEM?
- Over the past five years, TEM grew revenue faster — CRL at a 5.77% CAGR versus TEM at 42.06%.
Go deeper
Dig into the metrics
Charles River Laboratories International P/E ratioTempus AI P/E ratioCharles River Laboratories International dividend yieldTempus AI dividend yieldCharles River Laboratories International ROETempus AI ROECharles River Laboratories International operating marginTempus AI operating marginCharles River Laboratories International revenue growthTempus AI revenue growthCharles River Laboratories International free cash flowTempus AI free cash flow
Charles River Laboratories International & Tempus AI appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified June 13, 2026.