The Cooper Companies, Inc. (COO) vs Charles River Laboratories International, Inc. (CRL)
COO leads on 10 of 12 compared metrics.
A side-by-side comparison of The Cooper Companies, Inc. and Charles River Laboratories International, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of June 14, 2026. The ● marks the stronger figure on each row (cheaper multiple, higher margin/return).
COO
The Cooper Companies, Inc.
$67.88Healthcare
CRL
Charles River Laboratories International, Inc.
$187.51Healthcare
Total return — COO vs CRL
growth of $100 · last 26yCOO +1395.2%CRL +752.3%COO compounded faster
COO CRL
COO vs CRL: by the numbers
- •COO is the larger company ($13.24B vs $9.03B market cap).
- •COO is profitable (5.57% net margin) while CRL runs a net loss (-4.59%).
- •COO grew revenue faster over the past five years (9.73% vs 5.77% CAGR).
Which is better, COO or CRL?
Metric tally: COO 10 · CRL 2It depends on what you're optimizing for:
GrowthCOO(faster 5Y revenue CAGR)
QualityCRL(higher ROIC)
Metrics side by side
Valuation
| Metric | COO | CRL |
|---|---|---|
| P/E ratio | 57.53 | — |
| Forward P/E | 14.67● | 15.21 |
| P/S ratio | 3.13 | 2.28● |
| P/B ratio | 1.61● | 3.12 |
| EV / EBITDA | 17.97● | 41.45 |
| FCF yield | 4.30% | 4.26% |
Profitability
| Metric | COO | CRL |
|---|---|---|
| Gross margin | 64.37%● | 31.86% |
| Operating margin | 11.77% | 11.77% |
| Net margin | 5.57%● | -4.59% |
| ROE | 2.86%● | -6.28% |
| ROIC | 3.98% | 8.36%● |
Growth (annualized)
| Metric | COO | CRL |
|---|---|---|
| Revenue CAGR (5Y) | 9.73%● | 5.77% |
| EPS CAGR (5Y) | -17.30%● | -40.99% |
| FCF CAGR (5Y) | 6.61%● | -3.98% |
| Total return CAGR (5Y) | -6.25%● | -11.83% |
Frequently asked
- Which is better, COO or CRL?
- It depends on your goal. growth: COO (faster 5Y revenue CAGR); quality: CRL (higher ROIC). Across all compared metrics, COO leads 10 to 2.
- Which has grown faster, COO or CRL?
- Over the past five years, COO grew revenue faster — COO at a 9.73% CAGR versus CRL at 5.77%.
- Is COO or CRL more profitable?
- COO runs the higher net margin — COO at 5.57% versus CRL at -4.59%.
- Which has been the better investment, COO or CRL?
- Over the past 10-year, CRL delivered the higher annualized total return — COO at 5.23% versus CRL at 8.26%. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Cooper Companies P/E ratioCharles River Laboratories International P/E ratioCooper Companies dividend yieldCharles River Laboratories International dividend yieldCooper Companies ROECharles River Laboratories International ROECooper Companies operating marginCharles River Laboratories International operating marginCooper Companies revenue growthCharles River Laboratories International revenue growthCooper Companies free cash flowCharles River Laboratories International free cash flow
Cooper Companies & Charles River Laboratories International appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified June 14, 2026.