Basis: Trailing twelve months (TTM). Source: stored company filings and market data; unavailable inputs remain N/A.
Is the operating margin high or low?
The operating margin of -87.33% is 86% above its 5-year average of -606.23%, near the high end of its 5-year range (-3889.61%–79.35%).
90.73% above its 12-month average of -942.54%.
Reported quarterly operating margin; no daily interpolation. Q2 FY2026 (2026-06-30): -918.95%.
OPERATING MARGIN
-87.33%
OPERATING MARGIN AVG TTM
-942.54%
OPERATING MARGIN AVG 3Y
-404.01%
OPERATING MARGIN AVG 5Y
-606.23%
OPERATING MARGIN AVG 10Y
-823.72%
OPERATING MARGIN AVG 15Y
N/A
OPERATING MARGIN AVG 20Y
N/A
CURRENT VS TTM AVG
+90.73%
CURRENT VS 3Y AVG
+78.38%
CURRENT VS 5Y AVG
+85.59%
CURRENT VS 10Y AVG
+89.40%
CURRENT VS 15Y AVG
N/A
CURRENT VS 20Y AVG
N/A
SECTOR MEDIAN · HEALTHCARE
0.00%
median of 862 covered companies
CURRENT VS SECTOR MEDIAN
N/A
vs the sector median at left
Zymeworks Inc.
Market Cap
$1.89B
Operating Margin
-87.33%
TTM Avg
-942.54%
3Y Avg
-404.01%
5Y Avg
-606.23%
Market Cap
$1.89B
Operating Margin
-1.12%
TTM Avg
-4.89%
3Y Avg
-11.52%
5Y Avg
-13.12%
Market Cap
$1.89B
Operating Margin
-873.87%
TTM Avg
-1020.17%
3Y Avg
-1557.98%
5Y Avg
-1038.65%
Market Cap
$1.87B
Operating Margin
0.00%
TTM Avg
0.00%
3Y Avg
0.00%
5Y Avg
0.00%
Market Cap
$1.86B
Operating Margin
50.14%
TTM Avg
6.82%
3Y Avg
-32.12%
5Y Avg
-473.91%
Market Cap
$1.92B
Operating Margin
-18.48%
TTM Avg
-24.30%
3Y Avg
-28.12%
5Y Avg
-27.55%
Market Cap
$1.85B
Operating Margin
-3084.76%
TTM Avg
-3233.57%
3Y Avg
-1812.12%
5Y Avg
-1208.08%
Market Cap
$1.94B
Operating Margin
0.00%
TTM Avg
0.00%
3Y Avg
0.00%
5Y Avg
0.00%
Market Cap
$1.84B
Operating Margin
0.00%
TTM Avg
0.00%
3Y Avg
-41.96%
5Y Avg
-55.47%
| NAME | MARKET CAP | OPERATING MARGIN | TTM | 3Y | 5Y |
|---|---|---|---|---|---|
| Zymeworks Inc. (ZYME) | $1.89B | -87.33% | -942.54% | -404.01% | -606.23% |
| BioLife Solutions, Inc. (BLFS)vs › | $1.89B | -1.12% | -4.89% | -11.52% | -13.12% |
| Agios Pharmaceuticals, Inc. (AGIO)vs › | $1.89B | -873.87% | -1020.17% | -1557.98% | -1038.65% |
| Trevi Therapeutics, Inc. (TRVI)vs › | $1.87B | 0.00% | 0.00% | 0.00% | 0.00% |
| Novavax, Inc. (NVAX)vs › | $1.86B | 50.14% | 6.82% | -32.12% | -473.91% |
| Establishment Labs Holdings Inc. (ESTA)vs › | $1.92B | -18.48% | -24.30% | -28.12% | -27.55% |
| Immunome, Inc. (IMNM)vs › | $1.85B | -3084.76% | -3233.57% | -1812.12% | -1208.08% |
| Mineralys Therapeutics, Inc. (MLYS)vs › | $1.94B | 0.00% | 0.00% | 0.00% | 0.00% |
| Palvella Therapeutics, Inc. (PVLA)vs › | $1.84B | 0.00% | 0.00% | -41.96% | -55.47% |
| Astrana Health, Inc. (ASTH)vs › | $1.83B | 2.61% | 3.43% | 5.52% | 6.07% |
Gross Margin
100.0%
Operating Margin
-87.3%
Operating Margin = Operating Income / Revenue
Operating margin is the percentage of revenue remaining after operating expenses, reflecting operating efficiency.
Expanded definitions: Investopedia, Wikipedia, Corporate Finance Institute
| DATE | OPERATING MARGIN |
|---|---|
| 2026-06-30 | -918.95% |
| 2026-03-31 | -1956.73% |
| 2025-12-31 | -1755.55% |
| 2025-09-30 | -80.07% |
| 2025-06-30 | -1.38% |
| 2025-03-31 | -94.48% |
| 2024-12-31 | -71.60% |
| 2024-09-30 | -213.78% |
| 2024-06-30 | -222.87% |
| 2024-03-31 | -376.89% |
| 2023-12-31 | -138.37% |
| 2023-09-30 | -201.36% |
| 2023-06-30 | -772.84% |
| 2023-03-31 | -76.68% |
| 2022-12-31 | 79.35% |
| 2022-09-30 | -1914.03% |
| 2022-06-30 | -1209.54% |
| 2022-03-31 | -3793.63% |
| 2021-12-31 | -205.58% |
| 2021-09-30 | -1387.12% |
| 2021-06-30 | -3889.61% |
| 2021-03-31 | -6977.48% |
| 2020-12-31 | -239.45% |
| 2020-09-30 | -2788.27% |
| 2020-06-30 | -326.47% |
| 2020-03-31 | -433.91% |
| 2019-12-31 | -3929.25% |
| 2019-09-30 | -427.02% |
| 2019-06-30 | -373.41% |
| 2019-03-31 | -122.04% |
| 2018-12-31 | 29.51% |
| 2018-09-30 | -951.07% |
| 2018-06-30 | -9.16% |
| 2018-03-31 | -50277.50% |
| 2017-12-31 | 66.58% |
| 2017-09-30 | -14031.09% |
| 2017-06-30 | -687.93% |
| 2017-03-31 | -7132.61% |
| 2016-12-31 | -472.13% |
| 2016-09-30 | -508.79% |
| 2016-06-30 | -103.04% |
| 2016-03-31 | -3717.18% |
| 2015-12-31 | -550.24% |
