Novavax, Inc. (NVAX) vs Zymeworks Inc. (ZYME)
A side-by-side comparison of Novavax, Inc. and Zymeworks Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
NVAX
Novavax, Inc.
$11.32HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT
ZYME
Zymeworks Inc.
$25.65HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT
Total return — NVAX vs ZYME
growth of $100 · dividends reinvested · last 9yNVAX -23.4% (-2.9%/yr)ZYME +101.6% (+8.1%/yr)ZYME compounded faster over this window
NVAX ZYME
NVAX vs ZYME: by the numbers
- •ZYME is the larger company ($1.89B vs $1.86B market cap).
- •Both run net losses; NVAX's is the smaller (-59.87% vs -404.00% net margin).
- •NVAX grew revenue faster over the past five years (118.86% vs 12.35% CAGR).
Metrics side by side
Valuation
| Metric | NVAX | ZYME |
|---|---|---|
| Forward P/E | N/A | 24.73 |
| P/S ratio | 4.50 | 50.83 |
| P/B ratio | N/A | 23.48 |
Profitability
| Metric | NVAX | ZYME |
|---|---|---|
| Gross margin | 93.67% | 100.00% |
| Operating margin | 50.14% | -87.33% |
| Net margin | -59.87% | -404.00% |
| ROE | N/A | -186.63% |
| ROIC | -36.37% | -44.06% |
Growth (annualized)
| Metric | NVAX | ZYME |
|---|---|---|
| Revenue CAGR (5Y) | 118.86% | 12.35% |
| Total return CAGR (5Y) | -40.61% | -1.37% |
Frequently asked
- Which has grown faster, NVAX or ZYME?
- Over the past five years, NVAX grew revenue faster — NVAX at a 118.86% CAGR versus ZYME at 12.35%.
- How have NVAX and ZYME total returns compared?
- Over the past 5 years, NVAX delivered -40.61% and ZYME delivered -1.37% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Novavax ROEZymeworks ROENovavax operating marginZymeworks operating marginNovavax revenue growthZymeworks revenue growthNovavax free cash flowZymeworks free cash flow
Novavax & Zymeworks appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.