Basis: Trailing twelve months (TTM net income over TTM revenue). Source: stored company filings and market data; unavailable inputs remain N/A.
Is the net profit margin high or low?
The net profit margin of -89.09% is 11% below its 5-year average of -79.98%, near the high end of its 5-year range (-44759.66%–0.00%).
20.84% above its 12-month average of -112.54%.
Reported quarterly profit margin; no daily interpolation. Q2 FY2026 (2026-06-30): -47.64%.
NET PROFIT MARGIN
-89.09%
NET PROFIT MARGIN AVG TTM
-112.54%
NET PROFIT MARGIN AVG 3Y
-5463.45%
NET PROFIT MARGIN AVG 5Y
-79.98%
NET PROFIT MARGIN AVG 10Y
-29.10%
NET PROFIT MARGIN AVG 15Y
0.00%
NET PROFIT MARGIN AVG 20Y
0.00%
CURRENT VS TTM AVG
+20.84%
CURRENT VS 3Y AVG
+98.37%
CURRENT VS 5Y AVG
-11.39%
CURRENT VS 10Y AVG
-206.19%
CURRENT VS 15Y AVG
N/A
CURRENT VS 20Y AVG
N/A
SECTOR MEDIAN · HEALTHCARE
0.00%
median of 752 covered companies
CURRENT VS SECTOR MEDIAN
N/A
vs the sector median at left
Iovance Biotherapeutics, Inc.
Market Cap
$5.90B
Net Profit Margin
-89.09%
TTM Avg
-112.54%
3Y Avg
-5463.45%
5Y Avg
-79.98%
Market Cap
$5.91B
Net Profit Margin
67.88%
TTM Avg
22.01%
3Y Avg
16.68%
5Y Avg
14.76%
Market Cap
$6.01B
Net Profit Margin
-236.95%
TTM Avg
-945.70%
3Y Avg
-3296.24%
5Y Avg
-3620.73%
Market Cap
$5.74B
Net Profit Margin
9.59%
TTM Avg
-0.75%
3Y Avg
21.75%
5Y Avg
-53.79%
Market Cap
$5.68B
Net Profit Margin
-3602.68%
TTM Avg
-5857.26%
3Y Avg
-13524.50%
5Y Avg
-10844.39%
Market Cap
$5.53B
Net Profit Margin
-10.21%
TTM Avg
-9.94%
3Y Avg
-7.18%
5Y Avg
-7.18%
Market Cap
$6.33B
Net Profit Margin
-85.59%
TTM Avg
-151.92%
3Y Avg
-327.14%
5Y Avg
-585.95%
Market Cap
$5.34B
Net Profit Margin
-3.80%
TTM Avg
-2.80%
3Y Avg
-38.10%
5Y Avg
-60.79%
| NAME | MARKET CAP | NET PROFIT MARGIN | TTM | 3Y | 5Y |
|---|---|---|---|---|---|
| Iovance Biotherapeutics, Inc. (IOVA) | $5.90B | -89.09% | -112.54% | -5463.45% | -79.98% |
| Ligand Pharmaceuticals Incorporated (LGND)vs › | $5.91B | 67.88% | 22.01% | 16.68% | 14.76% |
| GRAIL Inc. (GRAL)vs › | $6.01B | -236.95% | -945.70% | -3296.24% | -3620.73% |
| Kiniksa Pharmaceuticals International, plc (KNSA)vs › | $5.74B | 9.59% | -0.75% | 21.75% | -53.79% |
| CG Oncology Inc. (CGON)vs › | $5.68B | -3602.68% | -5857.26% | -13524.50% | -10844.39% |
| MiniMed Group, Inc. Common Stock (MMED)vs › | $5.53B | -10.21% | -9.94% | -7.18% | -7.18% |
| RadNet, Inc. (RDNT)vs › | $5.52B | -0.93% | -0.38% | 0.04% | 0.11% |
| Rhythm Pharmaceuticals, Inc. (RYTM)vs › | $6.33B | -85.59% | -151.92% | -327.14% | -585.95% |
| PTC Therapeutics, Inc. (PTCT)vs › | $5.34B | -3.80% | -2.80% | -38.10% | -60.79% |
| Doximity, Inc. (DOCS)vs › | $5.32B | 25.48% | 34.77% | 31.87% | 32.80% |
Operating Margin
-153.1%
Net Profit Margin
-89.1%
Net Profit Margin = Net Income / Revenue
Net profit margin is the percentage of revenue that becomes net income after all expenses, taxes, and interest.
Expanded definitions: Investopedia, Wikipedia, Corporate Finance Institute
| DATE | NET PROFIT MARGIN |
|---|---|
| 2026-06-30 | -47.64% |
| 2026-03-31 | -110.66% |
| 2025-12-31 | -82.87% |
| 2025-09-30 | -135.28% |
| 2025-06-30 | -186.25% |
| 2025-03-31 | -235.51% |
| 2024-12-31 | -106.60% |
| 2024-09-30 | -142.67% |
| 2024-06-30 | -312.16% |
| 2024-03-31 | -15800.84% |
| 2023-12-31 | -24145.02% |
| 2023-09-30 | -24255.86% |
| 2023-06-30 | -44759.66% |
| 2023-03-31 | 0.00% |
| 2022-12-31 | 0.00% |
| 2022-09-30 | 0.00% |
| 2022-06-30 | 0.00% |
| 2022-03-31 | 0.00% |
| 2021-12-31 | 0.00% |
| 2021-09-30 | 0.00% |
| 2021-06-30 | 0.00% |
| 2021-03-31 | 0.00% |
| 2020-12-31 | 0.00% |
| 2020-09-30 | 0.00% |
| 2020-06-30 | 0.00% |
| 2020-03-31 | 0.00% |
| 2019-12-31 | 0.00% |
| 2019-09-30 | 0.00% |
| 2019-06-30 | 0.00% |
| 2019-03-31 | 0.00% |
| 2018-12-31 | 0.00% |
| 2018-09-30 | 0.00% |
| 2018-06-30 | 0.00% |
| 2018-03-31 | 0.00% |
| 2017-12-31 | 0.00% |
| 2017-09-30 | 0.00% |
| 2017-06-30 | 0.00% |
| 2017-03-31 | 0.00% |
| 2016-12-31 | 0.00% |
| 2016-09-30 | 0.00% |
| 2016-06-30 | 0.00% |
| 2016-03-31 | 0.00% |
| 2015-12-31 | 0.00% |
| 2015-09-30 | 0.00% |
| 2015-06-30 | 0.00% |
| 2015-03-31 | 0.00% |
| 2014-12-31 | 0.00% |
| 2014-09-30 | 0.00% |
| 2014-06-30 | 0.00% |
| 2014-03-31 | 0.00% |
| 2013-12-31 | 0.00% |
| 2013-09-30 | 0.00% |
| 2013-06-30 | 0.00% |
| 2013-03-31 | 0.00% |
| 2012-12-31 | 0.00% |
| 2012-09-30 | 0.00% |
| 2012-06-30 | 0.00% |
| 2012-03-31 | 0.00% |
| 2011-12-31 | 0.00% |
| 2011-09-30 | 0.00% |
| 2011-06-30 | 0.00% |
| 2011-03-31 | 0.00% |
| 2010-12-31 | 0.00% |
| 2010-09-30 | 0.00% |
| 2010-06-30 | 0.00% |
| 2010-03-31 | 0.00% |
| 2009-12-31 | 0.00% |
| 2009-09-30 | 0.00% |
| 2009-06-30 | 0.00% |
| 2009-03-31 | 0.00% |
| 2008-12-31 | 0.00% |
| 2008-09-30 | 0.00% |
| 2008-06-30 | 0.00% |
| 2008-03-31 | 0.00% |
