Basis: Trailing twelve months (TTM), to the latest fiscal quarter end. Source: stored company filings and market data; unavailable inputs remain N/A.
Is the return on invested capital (ROIC) high or low?
The return on invested capital (ROIC) of -50.82% is 62% below its 5-year average of -31.28%, near the low end of its 5-year range (-56.21%–3.44%).
As of the fiscal period ended Tuesday, June 30, 2026. 0.99% above its 12-month average of -51.33%.
Trailing-twelve-month return on invested capital at each fiscal quarter end; no daily interpolation. Q2 FY2026 (2026-06-30): -50.82%.
RETURN ON INVESTED CAPITAL (ROIC)
-50.82%
RETURN ON INVESTED CAPITAL (ROIC) AVG TTM
-51.33%
RETURN ON INVESTED CAPITAL (ROIC) AVG 3Y
-35.91%
RETURN ON INVESTED CAPITAL (ROIC) AVG 5Y
-31.28%
RETURN ON INVESTED CAPITAL (ROIC) AVG 10Y
-27.27%
RETURN ON INVESTED CAPITAL (ROIC) AVG 15Y
N/A
RETURN ON INVESTED CAPITAL (ROIC) AVG 20Y
N/A
CURRENT VS TTM AVG
+0.99%
CURRENT VS 3Y AVG
-41.50%
CURRENT VS 5Y AVG
-62.46%
CURRENT VS 10Y AVG
-86.34%
CURRENT VS 15Y AVG
N/A
CURRENT VS 20Y AVG
N/A
SECTOR MEDIAN · HEALTHCARE
-33.87%
median of 703 covered companies
CURRENT VS SECTOR MEDIAN
-50.05%
vs the sector median at left
Denali Therapeutics Inc.
Market Cap
$3.13B
Return on Invested Capital (ROIC)
-50.82%
TTM Avg
-51.33%
3Y Avg
-35.91%
5Y Avg
-31.28%
Market Cap
$3.06B
Return on Invested Capital (ROIC)
9.95%
TTM Avg
-25.98%
3Y Avg
-51.77%
5Y Avg
-51.95%
Market Cap
$3.07B
Return on Invested Capital (ROIC)
-66.60%
TTM Avg
-119.97%
3Y Avg
-72.56%
5Y Avg
-159.91%
Market Cap
$3.06B
Return on Invested Capital (ROIC)
-13.88%
TTM Avg
-29.89%
3Y Avg
-36.62%
5Y Avg
-30.08%
Market Cap
$3.35B
Return on Invested Capital (ROIC)
-409.85%
TTM Avg
-257.76%
3Y Avg
-257.76%
5Y Avg
-257.76%
Market Cap
$2.88B
Return on Invested Capital (ROIC)
-58.28%
TTM Avg
-46.81%
3Y Avg
-91.88%
5Y Avg
-70.41%
Market Cap
$3.40B
Return on Invested Capital (ROIC)
-0.93%
TTM Avg
1.17%
3Y Avg
-16.63%
5Y Avg
-13.35%
Market Cap
$3.42B
Return on Invested Capital (ROIC)
6.25%
TTM Avg
16.80%
3Y Avg
-7.33%
5Y Avg
-16.60%
Market Cap
$3.44B
Return on Invested Capital (ROIC)
-79.40%
TTM Avg
-65.84%
3Y Avg
-73.62%
5Y Avg
-96.54%
| NAME | MARKET CAP | RETURN ON INVESTED CAPITAL (ROIC) | TTM | 3Y | 5Y |
|---|---|---|---|---|---|
| Denali Therapeutics Inc. (DNLI) | $3.13B | -50.82% | -51.33% | -35.91% | -31.28% |
| Arcutis Biotherapeutics, Inc. (ARQT)vs › | $3.06B | 9.95% | -25.98% | -51.77% | -51.95% |
| Amylyx Pharmaceuticals, Inc. (AMLX)vs › | $3.07B | -66.60% | -119.97% | -72.56% | -159.91% |
| Enliven Therapeutics, Inc. (ELVN)vs › | $3.06B | -13.88% | -29.89% | -36.62% | -30.08% |
| Parabilis Medicines, Inc. (PBLS)vs › | $3.35B | -409.85% | -257.76% | -257.76% | -257.76% |
| Dyne Therapeutics, Inc. (DYN)vs › | $2.88B | -58.28% | -46.81% | -91.88% | -70.41% |
| CareDx, Inc (CDNA)vs › | $3.40B | -0.93% | 1.17% | -16.63% | -13.35% |
| Acadia Pharmaceuticals Inc. (ACAD)vs › | $3.42B | 6.25% | 16.80% | -7.33% | -16.60% |
| Pulse Biosciences, Inc. (PLSE)vs › | $3.44B | -79.40% | -65.84% | -73.62% | -96.54% |
| TransMedics Group, Inc. (TMDX)vs › | $2.82B | 5.87% | 7.96% | -0.22% | -9.17% |
ROIC
-50.8%
ROE
-61.2%
ROIC = NOPAT / Invested Capital, where NOPAT = Operating Income × (1 − effective tax rate) and Invested Capital = Total Assets − (Current Liabilities − Short-Term Debt)
Return on invested capital measures the after-tax operating return a company earns on the capital invested in the business. TGMCharts computes it from reported statements: trailing-twelve-month operating income after tax, over invested capital at the latest balance sheet — total assets less the non-interest-bearing current liabilities (payables, accruals, deferred revenue) that fund them; short-term debt stays in the capital base. The tax rate is the period's own effective rate (income tax ÷ pretax income), capped at 45%; when pretax income is zero or negative, or the tax line is a net benefit, no tax is deducted — the operating figure is shown untaxed rather than adjusted by an assumed rate. Not shown for banks, insurers or funds.
Expanded definitions: Investopedia, Wikipedia, Corporate Finance Institute
| DATE | RETURN ON INVESTED CAPITAL (ROIC) |
|---|---|
| 2026-06-30 | -50.82% |
| 2026-03-31 | -46.93% |
| 2025-12-31 | -53.07% |
| 2025-09-30 | -56.21% |
| 2025-06-30 | -49.63% |
| 2025-03-31 | -43.68% |
| 2024-12-31 | -38.31% |
| 2024-09-30 | -35.64% |
| 2024-06-30 | -33.66% |
| 2024-03-31 | -12.92% |
| 2023-12-31 | -18.28% |
| 2023-09-30 | -14.54% |
| 2023-06-30 | -13.20% |
| 2023-03-31 | -38.80% |
| 2022-12-31 | -31.08% |
| 2022-09-30 | -36.05% |
| 2022-06-30 | -30.78% |
| 2022-03-31 | -29.71% |
| 2021-12-31 | -28.83% |
| 2021-09-30 | 1.77% |
| 2021-06-30 | 3.44% |
| 2021-03-31 | 3.39% |
| 2020-12-31 | 4.03% |
| 2020-09-30 | -24.78% |
| 2020-06-30 | -38.91% |
| 2020-03-31 | -35.58% |
| 2019-12-31 | -41.97% |
| 2019-09-30 | -14.51% |
| 2019-06-30 | -11.59% |
| 2019-03-31 | -9.97% |
| 2018-12-31 | -7.37% |
| 2018-09-30 | -28.20% |
| 2018-06-30 | -23.83% |
| 2018-03-31 | -15.78% |
| 2017-12-31 | -19.07% |
| 2017-09-30 | -43.20% |
| 2017-06-30 | -40.71% |
| 2016-12-31 | -31.39% |
