Basis: Current FMP quote-based enterprise value / four-quarter operating income plus matched D&A. Source: stored company filings and market data; unavailable inputs remain N/A.
Is the EV/EBITDA ratio high or low?
The EV/EBITDA ratio of 3.25x is 46% above its estimated 3-year average of 2.23x, near the low end of its estimated 3-year range (0.00x–20.97x).
As of 2026-10-06T17:53:19.337Z. 57.73% below its estimated 12-month average of 7.69x.
Calculation as of: 2026-10-06T17:53:19.337Z.
Quote observation: 2026-10-06T17:50:00.000Z. Amounts in USD. The price header may show a later quote.
FMP input reference: 2f01081ea3fc0a51e4cf91d063b31ee616ec5173ab430d737d4f5d2ff49fd95f
Historical values estimate market capitalization from statement-period weighted shares. Comparisons with the current quote-based value are approximate. Only filing versions delivered by FMP are available for the historical calculation. Historical series through 2026-10-05.
Historical values estimate market capitalization from statement-period weighted shares. Comparisons with the current quote-based value are approximate. Only filing versions delivered by FMP are available for the historical calculation.
EV/EBITDA RATIO
3.25x
EV/EBITDA RATIO AVG TTM
7.69x
EV/EBITDA RATIO AVG 3Y
N/A
EV/EBITDA RATIO AVG 5Y
N/A
EV/EBITDA RATIO AVG 10Y
N/A
EV/EBITDA RATIO AVG 15Y
N/A
EV/EBITDA RATIO AVG 20Y
N/A
CURRENT VS TTM AVG
-57.73%
CURRENT VS 3Y AVG
N/A
CURRENT VS 5Y AVG
N/A
CURRENT VS 10Y AVG
N/A
CURRENT VS 15Y AVG
N/A
CURRENT VS 20Y AVG
N/A
SECTOR MEDIAN · HEALTHCARE
15.88x
median of 214 covered companies
CURRENT VS SECTOR MEDIAN
-79.54%
vs the sector median at left
Spero Therapeutics, Inc.
Market Cap
$68.32M
EV/EBITDA Ratio
3.25x
TTM Avg
7.69x
3Y Avg
N/A
5Y Avg
N/A
Market Cap
$69.75M
EV/EBITDA Ratio
262.40x
TTM Avg
103.53x
3Y Avg
75.29x
5Y Avg
64.49x
Market Cap
$71.42M
EV/EBITDA Ratio
N/A
TTM Avg
161.81x
3Y Avg
161.81x
5Y Avg
161.81x
| NAME | MARKET CAP | EV/EBITDA RATIO | TTM | 3Y | 5Y |
|---|---|---|---|---|---|
| Spero Therapeutics, Inc. (SPRO) | $68.32M | 3.25x | 7.69x | N/A | N/A |
| Tiziana Life Sciences Ltd (TLSA)vs › | $68.40M | N/A | N/A | N/A | N/A |
| iBio, Inc. (IBIO)vs › | $68.17M | N/A | N/A | N/A | N/A |
| Fortress Biotech, Inc. (FBIO)vs › | $68.09M | N/A | N/A | N/A | N/A |
| Champions Oncology, Inc. (CSBR)vs › | $69.75M | 262.40x | 103.53x | 75.29x | 64.49x |
| XBiotech Inc. (XBIT)vs › | $66.46M | N/A | N/A | N/A | N/A |
| Cingulate Inc. (CING)vs › | $66.00M | 0.23x | 0.03x | 0.03x | 0.03x |
| MindWalk Holdings Corp. (HYFT)vs › | $71.42M | N/A | 161.81x | 161.81x | 161.81x |
| Gain Therapeutics, Inc. (GANX)vs › | $71.66M | N/A | N/A | N/A | N/A |
| Gossamer Bio, Inc. (GOSS)vs › | $64.80M | N/A | N/A | N/A | N/A |
At 3.3, EV/EBITDA is near its estimated 3-year median — higher than 62% of readings in its estimated 3-year history.
Historical values estimate market capitalization from statement-period weighted shares. Comparisons with the current quote-based value are approximate. Only filing versions delivered by FMP are available for the historical calculation.
estimated 3-year low
0.0
median
1.1
estimated 3-year high
21.0
EV/EBITDA = Enterprise Value / EBITDA (TTM)
Enterprise value to EBITDA is a capital-structure-neutral valuation multiple, useful for comparing companies with different debt levels and tax rates.
Expanded definitions: Investopedia, Wikipedia, Corporate Finance Institute
| DATE | EV/EBITDA RATIO |
|---|---|
| 2026-10-05 | 3.07x |
| 2026-10-02 | 3.36x |
| 2026-10-01 | 4.03x |
| 2026-09-30 | 3.55x |
| 2026-09-29 | 3.46x |
| 2026-09-28 | 3.36x |
| 2026-09-25 | 3.75x |
| 2026-09-24 | 3.94x |
| 2026-09-23 | 4.03x |
| 2026-09-22 | 5.00x |
| 2026-09-21 | 2.88x |
| 2026-09-18 | 2.78x |
| 2026-09-17 | 2.69x |
| 2026-09-16 | 2.59x |
| 2026-09-15 | 2.78x |
| 2026-09-14 | 2.88x |
| 2026-09-11 | 2.78x |
| 2026-09-10 | 2.69x |
| 2026-09-09 | 3.17x |
| 2026-09-08 | 3.36x |
| 2026-09-04 | 3.55x |
| 2026-09-03 | 3.65x |
| 2026-09-02 | 3.65x |
| 2026-09-01 | 3.46x |
| 2026-08-31 | 3.65x |
| 2026-08-28 | 3.46x |
| 2026-08-27 | 3.55x |
| 2026-08-26 | 3.65x |
| 2026-08-25 | 3.75x |
| 2026-08-24 | 3.65x |
| 2026-08-21 | 3.65x |
| 2026-08-20 | 3.55x |
| 2026-08-19 | 3.75x |
| 2026-08-18 | 3.46x |
| 2026-08-17 | 3.36x |
| 2026-08-14 | 3.75x |
| 2026-08-13 | 3.84x |
| 2026-08-12 | 1.07x |
| 2026-08-11 | 1.24x |
| 2026-08-10 | 1.24x |
| 2026-08-07 | 1.37x |
| 2026-08-06 | 1.41x |
| 2026-08-05 | 1.37x |
| 2026-08-04 | 1.24x |
| 2026-08-03 | 0.90x |
| 2026-07-31 | 0.99x |
| 2026-07-30 | 1.12x |
| 2026-07-29 | 1.07x |
| 2026-07-28 | 1.12x |
| 2026-07-27 | 1.03x |
| 2026-07-24 | 1.07x |
| 2026-07-23 | 0.95x |
| 2026-07-22 | 1.41x |
| 2026-07-21 | 1.88x |
| 2026-07-20 | 2.13x |
| 2026-07-17 | 2.73x |
| 2026-07-16 | 2.69x |
| 2026-07-15 | 3.24x |
| 2026-07-14 | 3.24x |
| 2026-07-13 | 5.27x |
| 2026-07-10 | 4.93x |
| 2026-07-09 | 5.02x |
| 2026-07-08 | 5.23x |
| 2026-07-07 | 5.19x |
| 2026-07-06 | 5.31x |
| 2026-07-02 | 5.36x |
| 2026-07-01 | 5.44x |
| 2026-06-30 | 5.40x |
| 2026-06-29 | 5.61x |
| 2026-06-26 | 5.61x |
| 2026-06-25 | 4.59x |
| 2026-06-24 | 4.93x |
| 2026-06-23 | 5.15x |
| 2026-06-22 | 5.40x |
| 2026-06-18 | 5.70x |
| 2026-06-17 | 4.98x |
| 2026-06-16 | 7.77x |
| 2026-06-15 | 8.37x |
| 2026-06-12 | 8.11x |
| 2026-06-11 | 7.48x |
| 2026-06-10 | 6.80x |
| 2026-06-09 | 6.93x |
| 2026-06-08 | 7.65x |
| 2026-06-05 | 7.99x |
| 2026-06-04 | 8.66x |
| 2026-06-03 | 7.90x |
| 2026-06-02 | 8.03x |
| 2026-06-01 | 8.03x |
| 2026-05-29 | 8.03x |
| 2026-05-28 | 8.33x |
| 2026-05-27 | 8.45x |
| 2026-05-26 | 8.16x |
| 2026-05-22 | 7.73x |
| 2026-05-21 | 7.44x |
| 2026-05-20 | 7.18x |
| 2026-05-19 | 7.01x |
| 2026-05-18 | 6.97x |
| 2026-05-15 | 7.86x |
| 2026-05-14 | 7.73x |
| 2026-05-13 | 17.02x |
| 2026-05-12 | 17.96x |
| 2026-05-11 | 18.05x |
| 2026-05-08 | 18.15x |
| 2026-05-07 | 17.68x |
| 2026-05-06 | 17.87x |
| 2026-05-05 | 16.83x |
| 2026-05-04 | 17.58x |
| 2026-05-01 | 17.40x |
| 2026-04-30 | 17.68x |
| 2026-04-29 | 17.87x |
| 2026-04-28 | 19.18x |
| 2026-04-27 | 19.18x |
| 2026-04-24 | 19.84x |
| 2026-04-23 | 20.40x |
| 2026-04-22 | 20.97x |
| 2026-04-21 | 20.40x |
| 2026-04-20 | 20.78x |
| 2026-04-17 | 19.93x |
| 2026-04-16 | 19.28x |
| 2026-04-15 | 18.90x |
| 2026-04-14 | 20.22x |
| 2026-04-13 | 20.22x |
| 2026-04-10 | 19.18x |
| 2026-04-09 | 20.22x |
| 2026-04-08 | 19.65x |
| 2026-04-07 | 19.18x |
| 2026-04-06 | 18.62x |
| 2026-04-02 | 16.93x |
| 2026-04-01 | 17.11x |
| 2026-03-31 | 16.08x |
| 2026-03-30 | 15.14x |
| 2026-03-27 | 15.99x |
| 2024-11-14 | 0.56x |
| 2024-11-13 | 0.77x |
| 2024-11-12 | 0.80x |
| 2024-11-11 | 0.84x |
| 2024-11-08 | 0.80x |
| 2024-11-07 | 0.77x |
| 2024-11-06 | 0.77x |
| 2024-11-05 | 0.77x |
| 2024-11-04 | 0.70x |
| 2024-11-01 | 0.32x |
| 2024-10-31 | 0.50x |
| 2024-10-30 | 0.70x |
| 2024-10-29 | 0.77x |
| 2024-10-28 | 0.70x |
| 2024-10-25 | 0.84x |
| 2024-10-24 | 0.60x |
| 2024-10-23 | 0.60x |
| 2024-10-22 | 0.63x |
| 2024-10-21 | 0.67x |
| 2024-10-18 | 0.67x |
| 2024-10-17 | 0.70x |
| 2024-10-16 | 0.53x |
| 2024-10-15 | 0.39x |
| 2024-10-14 | 0.50x |
| 2024-10-11 | 0.56x |
| 2024-10-10 | 0.53x |
| 2024-10-09 | 0.53x |
| 2024-10-08 | 0.53x |
| 2024-10-07 | 0.74x |
| 2024-10-04 | 0.74x |
| 2024-10-03 | 0.70x |
| 2024-10-02 | 0.77x |
| 2024-10-01 | 0.77x |
| 2024-09-30 | 0.87x |
| 2024-09-27 | 0.77x |
| 2024-09-26 | 0.67x |
| 2024-09-25 | 0.67x |
| 2024-09-24 | 0.67x |
| 2024-09-23 | 0.74x |
| 2024-09-20 | 0.84x |
| 2024-09-19 | 0.94x |
| 2024-09-18 | 0.87x |
| 2024-09-17 | 0.84x |
| 2024-09-16 | 0.98x |
| 2024-09-13 | 0.98x |
| 2024-09-12 | 0.84x |
| 2024-09-11 | 0.87x |
| 2024-09-10 | 0.91x |
| 2024-09-09 | 0.98x |
| 2024-09-06 | 0.80x |
| 2024-09-05 | 0.84x |
| 2024-09-04 | 0.77x |
| 2024-09-03 | 0.87x |
| 2024-08-30 | 0.98x |
| 2024-08-29 | 0.98x |
| 2024-08-28 | 0.98x |
| 2024-08-27 | 1.01x |
| 2024-08-26 | 0.94x |
| 2024-08-23 | 0.98x |
| 2024-08-22 | 0.91x |
| 2024-08-21 | 0.98x |
| 2024-08-20 | 0.56x |
| 2024-08-19 | 0.63x |
| 2024-08-16 | 0.36x |
| 2024-08-15 | 0.43x |
| 2024-08-14 | 0.46x |
| 2024-08-13 | 0.63x |
| 2024-08-12 | 0.70x |
| 2024-08-09 | 0.67x |
| 2024-08-08 | 0.60x |
| 2024-08-07 | 0.50x |
| 2024-08-06 | 0.63x |
| 2024-07-29 | 0.00x |
| 2024-07-26 | 0.00x |
| 2024-07-17 | 0.10x |
| 2024-07-16 | 0.15x |
| 2024-07-15 | 0.03x |
| 2024-06-11 | 0.12x |
| 2024-06-06 | 0.03x |
| 2024-06-05 | 0.03x |
| 2024-05-28 | 0.00x |
| 2024-05-24 | 0.08x |
| 2024-05-23 | 0.10x |
| 2024-05-22 | 0.17x |
| 2024-05-21 | 0.17x |
| 2024-05-20 | 0.29x |
| 2024-05-17 | 0.37x |
| 2024-05-16 | 0.32x |
| 2024-05-15 | 0.70x |
| 2024-05-14 | 0.65x |
| 2024-05-13 | 0.77x |
| 2024-05-10 | 0.75x |
| 2024-05-09 | 0.87x |
| 2024-05-08 | 0.82x |
| 2024-05-07 | 0.80x |
| 2024-05-06 | 0.80x |
| 2024-05-03 | 0.72x |
| 2024-05-02 | 0.67x |
| 2024-05-01 | 0.53x |
| 2024-04-30 | 0.21x |
| 2024-04-29 | 0.26x |
| 2024-04-26 | 0.31x |
| 2024-04-25 | 0.24x |
| 2024-04-24 | 0.21x |
| 2024-04-23 | 0.26x |
| 2024-04-22 | 0.19x |
| 2024-04-19 | 0.16x |
| 2024-04-18 | 0.33x |
| 2024-04-17 | 0.41x |
| 2024-04-16 | 0.33x |
| 2024-04-15 | 0.48x |
| 2024-04-12 | 0.75x |
| 2024-04-11 | 0.92x |
| 2024-04-10 | 0.89x |
| 2024-04-09 | 0.87x |
| 2024-04-08 | 0.84x |
| 2024-04-05 | 0.77x |
| 2024-04-04 | 0.87x |
| 2024-04-03 | 1.11x |
| 2024-04-02 | 1.14x |
| 2024-04-01 | 1.11x |
| 2024-03-28 | 0.94x |
| 2024-03-27 | 1.01x |
| 2024-03-26 | 0.97x |
| 2024-03-25 | 0.87x |
| 2024-03-22 | 1.01x |
| 2024-03-21 | 0.97x |
| 2024-03-20 | 1.04x |
Showing the most recent 260 of 264 data points. The chart above shows the full history.
