Basis: Trailing twelve months (TTM net income over TTM revenue). Source: stored company filings and market data; unavailable inputs remain N/A.
Is the net profit margin high or low?
The net profit margin of -153.28% is 56% below its 5-year average of -98.10%, around the middle of its 5-year range (-299.89%–55.61%).
3.90% below its 12-month average of -147.53%.
Reported quarterly profit margin; no daily interpolation. Q2 FY2026 (2026-06-30): -200.48%.
NET PROFIT MARGIN
-153.28%
NET PROFIT MARGIN AVG TTM
-147.53%
NET PROFIT MARGIN AVG 3Y
-91.83%
NET PROFIT MARGIN AVG 5Y
-98.10%
NET PROFIT MARGIN AVG 10Y
-152.09%
NET PROFIT MARGIN AVG 15Y
-6145.66%
NET PROFIT MARGIN AVG 20Y
N/A
CURRENT VS TTM AVG
-3.90%
CURRENT VS 3Y AVG
-66.91%
CURRENT VS 5Y AVG
-56.24%
CURRENT VS 10Y AVG
-0.78%
CURRENT VS 15Y AVG
+97.51%
CURRENT VS 20Y AVG
N/A
SECTOR MEDIAN · HEALTHCARE
-0.06%
median of 853 covered companies
CURRENT VS SECTOR MEDIAN
-255366.67%
vs the sector median at left
Karyopharm Therapeutics Inc.
Market Cap
$15.24M
Net Profit Margin
-153.28%
TTM Avg
-147.53%
3Y Avg
-91.83%
5Y Avg
-98.10%
Market Cap
$15.24M
Net Profit Margin
-3011.52%
TTM Avg
0.00%
3Y Avg
0.00%
5Y Avg
-79.84%
Market Cap
$14.92M
Net Profit Margin
0.00%
TTM Avg
0.00%
3Y Avg
0.00%
5Y Avg
-2405.08%
Market Cap
$15.65M
Net Profit Margin
-3575.07%
TTM Avg
-1754.85%
3Y Avg
-877.42%
5Y Avg
-584.95%
Market Cap
$15.78M
Net Profit Margin
0.00%
TTM Avg
-6850.00%
3Y Avg
-4251.62%
5Y Avg
-4766.26%
Market Cap
$14.14M
Net Profit Margin
-39.61%
TTM Avg
-209.93%
3Y Avg
-392.71%
5Y Avg
-532.46%
Market Cap
$14.08M
Net Profit Margin
N/A
TTM Avg
N/A
3Y Avg
N/A
5Y Avg
N/A
Market Cap
$16.44M
Net Profit Margin
-219.50%
TTM Avg
-381.91%
3Y Avg
-332.62%
5Y Avg
-409.39%
Market Cap
$13.93M
Net Profit Margin
-8716.77%
TTM Avg
-1649.40%
3Y Avg
-960.30%
5Y Avg
-749.49%
| NAME | MARKET CAP | NET PROFIT MARGIN | TTM | 3Y | 5Y |
|---|---|---|---|---|---|
| Karyopharm Therapeutics Inc. (KPTI) | $15.24M | -153.28% | -147.53% | -91.83% | -98.10% |
| Cocrystal Pharma, Inc. (COCP)vs › | $15.24M | -3011.52% | 0.00% | 0.00% | -79.84% |
| Pasithea Therapeutics Corp. (KTTA)vs › | $14.92M | 0.00% | 0.00% | 0.00% | -2405.08% |
| Allarity Therapeutics, Inc. (ALLR)vs › | $15.65M | -3575.07% | -1754.85% | -877.42% | -584.95% |
| BioCardia, Inc. (BCDA)vs › | $15.78M | 0.00% | -6850.00% | -4251.62% | -4766.26% |
| Pulsenmore Ltd. Ordinary Shares (PLSM)vs › | $14.14M | -39.61% | -209.93% | -392.71% | -532.46% |
| Obsidian Therapeutics Inc. (OBX)vs › | $14.08M | N/A | N/A | N/A | N/A |
| Dyadic International, Inc. (DYAI)vs › | $16.44M | -219.50% | -381.91% | -332.62% | -409.39% |
| Vyome Holdings, Inc. (HIND)vs › | $13.93M | -8716.77% | -1649.40% | -960.30% | -749.49% |
| TScan Therapeutics, Inc. (TCRX)vs › | $16.55M | -1655.35% | -2892.23% | -1674.40% | -1597.52% |
Operating Margin
-56.2%
Net Profit Margin
-153.3%
Net Profit Margin = Net Income / Revenue
Net profit margin is the percentage of revenue that becomes net income after all expenses, taxes, and interest.
Expanded definitions: Investopedia, Wikipedia, Corporate Finance Institute
| DATE | NET PROFIT MARGIN |
|---|---|
| 2026-06-30 | -200.48% |
| 2026-03-31 | -63.86% |
| 2025-12-31 | -299.89% |
| 2025-09-30 | -75.21% |
| 2025-06-30 | -98.22% |
| 2025-03-31 | -78.17% |
| 2024-12-31 | -100.78% |
| 2024-09-30 | -82.70% |
| 2024-06-30 | 55.61% |
| 2024-03-31 | -112.79% |
| 2023-12-31 | -123.97% |
| 2023-09-30 | -95.83% |
| 2023-06-30 | -86.83% |
| 2023-03-31 | -88.19% |
| 2022-12-31 | -114.67% |
| 2022-09-30 | -100.50% |
| 2022-06-30 | -123.65% |
| 2022-03-31 | -86.84% |
| 2021-12-31 | 30.66% |
| 2021-09-30 | -137.47% |
| 2021-06-30 | -237.08% |
| 2021-03-31 | -246.84% |
| 2020-12-31 | -123.71% |
| 2020-09-30 | -250.76% |
| 2020-06-30 | -138.53% |
| 2020-03-31 | -291.82% |
| 2019-12-31 | -268.83% |
| 2019-09-30 | -314.60% |
| 2019-06-30 | -457.34% |
| 2019-03-31 | -42684.52% |
| 2018-12-31 | -28257.28% |
| 2018-09-30 | -20118.41% |
| 2018-06-30 | -169.20% |
| 2018-03-31 | -384.59% |
| 2017-12-31 | -2544.98% |
| 2017-09-30 | 0.00% |
| 2017-06-30 | -979566.67% |
| 2017-03-31 | -43995.59% |
| 2016-12-31 | -57308.51% |
| 2016-09-30 | -52968.75% |
| 2016-06-30 | -51115.25% |
| 2016-03-31 | 0.00% |
| 2015-12-31 | -116184.00% |
| 2015-09-30 | -40497.33% |
| 2015-06-30 | -21796.67% |
| 2015-03-31 | 0.00% |
| 2014-12-31 | -162050.00% |
| 2014-09-30 | -93923.81% |
| 2014-06-30 | -78242.86% |
| 2014-03-31 | -8008.19% |
| 2013-12-31 | -57838.10% |
| 2013-09-30 | 0.00% |
| 2013-06-30 | -5164.66% |
| 2013-03-31 | -2408.15% |
| 2012-12-31 | -12842.42% |
| 2012-09-30 | -10691.18% |
