Basis: Trailing twelve months (TTM). Source: stored company filings and market data; unavailable inputs remain N/A.
Is the operating margin high or low?
The operating margin of -56.17% is 33% above its 5-year average of -83.37%, around the middle of its 5-year range (-217.02%–37.19%).
4.77% above its 12-month average of -58.98%.
Reported quarterly operating margin; no daily interpolation. Q2 FY2026 (2026-06-30): -67.38%.
OPERATING MARGIN
-56.17%
OPERATING MARGIN AVG TTM
-58.98%
OPERATING MARGIN AVG 3Y
-78.54%
OPERATING MARGIN AVG 5Y
-83.37%
OPERATING MARGIN AVG 10Y
-132.40%
OPERATING MARGIN AVG 15Y
-6151.69%
OPERATING MARGIN AVG 20Y
N/A
CURRENT VS TTM AVG
+4.77%
CURRENT VS 3Y AVG
+28.49%
CURRENT VS 5Y AVG
+32.63%
CURRENT VS 10Y AVG
+57.57%
CURRENT VS 15Y AVG
+99.09%
CURRENT VS 20Y AVG
N/A
SECTOR MEDIAN · HEALTHCARE
0.00%
median of 863 covered companies
CURRENT VS SECTOR MEDIAN
N/A
vs the sector median at left
Karyopharm Therapeutics Inc.
Market Cap
$14.96M
Operating Margin
-56.17%
TTM Avg
-58.98%
3Y Avg
-78.54%
5Y Avg
-83.37%
Market Cap
$15.03M
Operating Margin
0.00%
TTM Avg
0.00%
3Y Avg
0.00%
5Y Avg
-4987.62%
Market Cap
$15.24M
Operating Margin
0.00%
TTM Avg
0.00%
3Y Avg
0.00%
5Y Avg
-79.33%
Market Cap
$15.54M
Operating Margin
2.94%
TTM Avg
9.21%
3Y Avg
11.00%
5Y Avg
11.87%
Market Cap
$15.68M
Operating Margin
-3939.06%
TTM Avg
-1969.53%
3Y Avg
-984.76%
5Y Avg
-656.51%
Market Cap
$15.78M
Operating Margin
0.00%
TTM Avg
-6897.41%
3Y Avg
-4279.04%
5Y Avg
-4845.03%
Market Cap
$14.11M
Operating Margin
-859.22%
TTM Avg
-477.88%
3Y Avg
-341.34%
5Y Avg
-316.87%
Market Cap
$14.11M
Operating Margin
-30.39%
TTM Avg
-233.67%
3Y Avg
-448.22%
5Y Avg
-530.52%
Market Cap
$13.81M
Operating Margin
N/A
TTM Avg
N/A
3Y Avg
N/A
5Y Avg
N/A
| NAME | MARKET CAP | OPERATING MARGIN | TTM | 3Y | 5Y |
|---|---|---|---|---|---|
| Karyopharm Therapeutics Inc. (KPTI) | $14.96M | -56.17% | -58.98% | -78.54% | -83.37% |
| Pasithea Therapeutics Corp. (KTTA)vs › | $15.03M | 0.00% | 0.00% | 0.00% | -4987.62% |
| Cocrystal Pharma, Inc. (COCP)vs › | $15.24M | 0.00% | 0.00% | 0.00% | -79.33% |
| Jin Medical International Ltd. (ZJYL)vs › | $15.54M | 2.94% | 9.21% | 11.00% | 11.87% |
| Allarity Therapeutics, Inc. (ALLR)vs › | $15.68M | -3939.06% | -1969.53% | -984.76% | -656.51% |
| BioCardia, Inc. (BCDA)vs › | $15.78M | 0.00% | -6897.41% | -4279.04% | -4845.03% |
| Vyome Holdings, Inc. (HIND)vs › | $14.11M | -859.22% | -477.88% | -341.34% | -316.87% |
| Pulsenmore Ltd. Ordinary Shares (PLSM)vs › | $14.11M | -30.39% | -233.67% | -448.22% | -530.52% |
| Obsidian Therapeutics Inc. (OBX)vs › | $13.81M | N/A | N/A | N/A | N/A |
| Sintx Technologies, Inc. (SINT)vs › | $13.99M | -1053.14% | -1090.26% | -1143.76% | -1293.19% |
Gross Margin
95.9%
Operating Margin
-56.2%
Operating Margin = Operating Income / Revenue
Operating margin is the percentage of revenue remaining after operating expenses, reflecting operating efficiency.
Expanded definitions: Investopedia, Wikipedia, Corporate Finance Institute
| DATE | OPERATING MARGIN |
|---|---|
| 2026-06-30 | -67.38% |
| 2026-03-31 | -76.31% |
| 2025-12-31 | -52.36% |
| 2025-09-30 | -34.56% |
| 2025-06-30 | -64.30% |
| 2025-03-31 | -110.80% |
| 2024-12-31 | -102.42% |
| 2024-09-30 | -67.77% |
| 2024-06-30 | -65.72% |
| 2024-03-31 | -101.91% |
| 2023-12-31 | -112.03% |
| 2023-09-30 | -86.81% |
| 2023-06-30 | -78.70% |
| 2023-03-31 | -79.85% |
| 2022-12-31 | -100.86% |
| 2022-09-30 | -85.32% |
| 2022-06-30 | -108.14% |
| 2022-03-31 | -72.55% |
| 2021-12-31 | 37.19% |
| 2021-09-30 | -116.25% |
| 2021-06-30 | -217.02% |
| 2021-03-31 | -225.16% |
| 2020-12-31 | -105.60% |
| 2020-09-30 | -220.83% |
| 2020-06-30 | -120.30% |
| 2020-03-31 | -261.09% |
| 2019-12-31 | -239.09% |
| 2019-09-30 | -299.65% |
| 2019-06-30 | -439.12% |
| 2019-03-31 | -41885.16% |
| 2018-12-31 | -27890.78% |
| 2018-09-30 | -20566.53% |
| 2018-06-30 | -172.60% |
| 2018-03-31 | -389.42% |
| 2017-12-31 | -2571.84% |
| 2017-09-30 | 0.00% |
| 2017-06-30 | -991733.33% |
| 2017-03-31 | -44527.94% |
| 2016-12-31 | -57797.87% |
| 2016-09-30 | -53629.17% |
| 2016-06-30 | -51654.24% |
| 2016-03-31 | 0.00% |
| 2015-12-31 | -117212.00% |
| 2015-09-30 | -40813.33% |
| 2015-06-30 | -22008.67% |
| 2015-03-31 | 0.00% |
| 2014-12-31 | -162137.50% |
| 2014-09-30 | -94019.05% |
| 2014-06-30 | -78323.81% |
| 2014-03-31 | -8018.71% |
| 2013-12-31 | -57847.62% |
| 2013-09-30 | 0.00% |
| 2013-06-30 | -5165.41% |
| 2013-03-31 | -2408.15% |
| 2012-12-31 | -12842.42% |
| 2012-09-30 | -10691.18% |
