Cocrystal Pharma, Inc. (COCP) vs Karyopharm Therapeutics Inc. (KPTI)
A side-by-side comparison of Cocrystal Pharma, Inc. and Karyopharm Therapeutics Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
COCP
Cocrystal Pharma, Inc.
$1.11HealthcareDelayed quote: Oct 6, 2026, 11:54 AM EDT
KPTI
Karyopharm Therapeutics Inc.
$0.67HealthcareDelayed quote: Oct 6, 2026, 12:00 PM EDT
Total return — COCP vs KPTI
growth of $100 · dividends reinvested · last 10yCOCP -99.4% (-39.6%/yr)KPTI -99.5% (-41.7%/yr)COCP compounded faster over this window
COCP KPTI
COCP vs KPTI: by the numbers
- •COCP is the larger company ($15M vs $15M market cap).
- •Both run net losses; KPTI's is the smaller (-153.28% vs -3011.52% net margin).
- •COCP grew revenue faster over the past five years (91.55% vs 7.47% CAGR).
Metrics side by side
Valuation
| Metric | COCP | KPTI |
|---|---|---|
| P/S ratio | 46.38 | 0.10 |
| P/B ratio | 14.66 | N/A |
Profitability
| Metric | COCP | KPTI |
|---|---|---|
| Gross margin | 0.00% | 95.88% |
| Operating margin | 0.00% | -56.17% |
| Net margin | -3011.52% | -153.28% |
| ROE | -951.92% | N/A |
| ROIC | -497.29% | N/A |
Growth (annualized)
| Metric | COCP | KPTI |
|---|---|---|
| Revenue CAGR (5Y) | 91.55% | 7.47% |
| Total return CAGR (5Y) | -37.50% | -62.18% |
Frequently asked
- Which has grown faster, COCP or KPTI?
- Over the past five years, COCP grew revenue faster — COCP at a 91.55% CAGR versus KPTI at 7.47%.
- How have COCP and KPTI total returns compared?
- Over the past 10 years, COCP delivered -39.76% and KPTI delivered -41.85% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Cocrystal Pharma ROEKaryopharm Therapeutics ROECocrystal Pharma operating marginKaryopharm Therapeutics operating marginCocrystal Pharma revenue growthKaryopharm Therapeutics revenue growthCocrystal Pharma free cash flowKaryopharm Therapeutics free cash flow
Cocrystal Pharma & Karyopharm Therapeutics appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.